Protein Alignment frma and Nep1

DIOPT Version :10

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_511056.2
• Gene: Nep1 / 31547
• FlyBaseID: FBgn0029843
• Length: 849
• Species: Drosophila melanogaster
• Alignment Length: 717
• Identity: 144/717 - (20%)
• Similarity: 262/717 - (36%)
• Gaps: 217/717 - (30%)

  Fly    25 ADPCQNFYKVACGNWSASHATDSYESFMDRLDYNYQEKLAD--------LLDNEREDDEPHFLQQ 81
            :|||::|::.|||.|:..|....     ||...:..|.|:|        :|:...::.:.....:
  Fly   193 SDPCEDFFQYACGTWNKMHPIPE-----DRSSISTFEVLSDQQQVILRAVLEEPIDERDNKATIK 252

  Fly    82 LRNFYTACRKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRL-QVLIDLNDSNTYDIWKQLM 145
            .:.|:.:|                  |:..|..::..|     || |||..|..      |..:
  Fly   253 AKTFFKSC------------------MDIPQIRKIGTG-----RLKQVLQSLGG------WPVI- 287

  Fly   146 SHRKHWDP-------------NTTNREPLTREMF---------------DKLWASLPKIPFPFKE 182
              .::|.|             .....||:..|::               |:|..:||.     ::
  Fly   288 --ERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPS-----RD 345

  Fly   183 YYWRELS---------------------------ELEEKIMSYGS--------EDDGFDSGDLVT 212
            ||.:|.|                           || ||::.:.:        |.|..|: .||.
  Fly   346 YYLKESSANDRRAYHRYMTQVALLLGADPATAAAEL-EKVVLFETQLVNVSLPEADRHDT-SLVY 408

  Fly   213 R---IPPFW-MMPWPNGNITYENLSQMA--HWLDIKANEFILTYIYMRL----KLVAEGVSTESW 267
            |   :|... ::|    .:.::...|.|  ..:.::.:|.::||....|    |::|
  Fly   409 RKMLLPELQELVP----EVQWQEYLQAALGPGIPLQEDEPLVTYGLHYLTEMGKILA-------- 461

  Fly   268 HIDRDQCAEQS--RQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQ-------KL----- 318
            |.||.......  |.::|..:..:.|....|::...:|..|.:| :.|:.|       ||
  Fly   462 HTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSE-RTRWSQCVEWTNKKLGVAVG 525

  Fly   319 -LANRNNFTRSTQHFLLGKLKRMRLRLS-ILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHIG 381
             |..|:||.:.::...|..:..:|...: :|..|.......|.:.:...|   :.::..|...:.
  Fly   526 ALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKAD---SMNERIGYPELL 587

  Fly   382 LNHSRSHKKYAQLWAIVFGRQLIPSRISKSDL---------------YPTQVRGYGT---YASAF 428
            .|.:...::|..|       .::|.....:.|               .|.....:.|   ..:||
  Fly   588 TNATELEQEYVNL-------TIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAF 645

  Fly   429 YIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHG-----VGSS 488
            |...:|.::.|..:|:|.||:...|..|.|..:|.::|||::||||.:|..|...|     ..::
  Fly   646 YNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNA 710

  Fly   489 AVDRELDRNPRFQQELGCLRRRFGRKRY--------------EKFADASGLELAYSAYFDTAQTD 539
            .::       .|::...|:..::.|.:.              |..||..||:.|:.|| ...:|.
  Fly   711 TIE-------AFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAY-KKWETL 767

  Fly   540 HKRNRSAEEL-VTQKQQFFHNFAQFFCSDKE------LLQAHDHGSDRKRVNDAVAHFEPFREAF 597
            |.|.:....| :|..|.||.|:||.:|....      .:::..|.....||...:::...|..|:
  Fly   768 HGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAY 832

  Fly   598 SC 599
            .|
  Fly   833 KC 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:472708	144/717 (20%)
Nep1	NP_511056.2	M13	194..847	CDD:341056	144/716 (20%)