Protein Alignment frma and Kel

DIOPT Version :10

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 737
• Identity: 152/737 - (20%)
• Similarity: 245/737 - (33%)
• Gaps: 251/737 - (34%)

  Fly    25 ADPCQNFYKVACGNWSASHATDSYESFMDRLDYNYQEKLADLLD-----NEREDDEPHFLQQLRN 84
            |.||.:|:..||.  .|:..::|:::..:    ..:.:|..||:     :....:|..|     .
  Rat    78 AAPCTDFFSFACE--KANGTSNSFQALAE----ENKSRLWKLLEAPGSWHLESGEEKAF-----Q 131

  Fly    85 FYTACRKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRLQVLIDLNDSNTYDIW-------- 141
            ||.:|                     :..:.:....|... :|::.:|...|....|
  Rat   132 FYNSC---------------------MDTDAIEASGTGPL-VQIIKELGGWNISGNWTFFDFNQN 174

  Fly   142 -KQLMSHRKHWD-----------PNTTNREPLTREMFD---------KLWASLPKIPFPFKEY-- 183
             :.|||...|:.           |..|....:.:..||         |::|.:      .:||
  Rat   175 LRLLMSQYGHFPFFRAYLHPHPAPPHTPIIQIDQPEFDILLQQDQEQKVYAQI------LREYVT 233

  Fly   184 YWRELSELEEKIMSYGSEDDGFDSGDLV--TRIPPFWMMPWPNGN--------ITYENLSQMA-- 236
            |...|..|   :.|...|.....|..:|  :|:..| :.|.....        :|.:.|.:||
  Rat   234 YLNRLGTL---LGSNPQEAQQHASWSIVFTSRLFQF-LRPQQQQQAQDKLFHVVTIDALQEMAPA 294

  Fly   237 -HWLDIKANEFI--------------LTYIYMRLKLVAEGVSTESWHIDRDQCAEQSRQILSHPA 286
             .||......|.              |.|:....:||.||:...|..|       ||..||.
  Rat   295 IDWLSCLQAIFTPMSLSPSQTLQVHDLDYLRNMSQLVEEGLLNHSEII-------QSYMILG--- 349

  Fly   287 AWLVEKNHP------------------RLKEEPVL------------------------------ 303
              ||:...|                  :|||.|.|
  Rat   350 --LVDTLSPALATKFQEARRELTQKLRKLKERPPLPAYPRWMKCVEQTGSFFEPTLAALFVHEAF 412

  Fly   304 --------QDIFAELKQRFGQKLLANRNNFTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRI 360
                    .::|||:|.....: |...:..:..|:...|.||.::::.:. .|:.:....|.:
  Rat   413 GPSIRSAAMELFAEIKDAVIVR-LKKLSWISEETRKEALNKLTQLQVEMG-APKRALKTEMAK-- 473

  Fly   361 ERHYRDVHMNASDYFGNLHIGLNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYA 425
             :.|.|:.:..|  |....:....|...:|....        |.|....:....|..|
  Rat   474 -QEYSDIQLGPS--FLQSFLSCVRSLQGRKVRSF--------LQPFPYHRWQKSPWSV------- 520

  Fly   426 SAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAV 490
            ||:|.|..::::.|..||:|||:..|.|..:.:.|:|.|:.|:|.|.|    ..|...| |..|.
  Rat   521 SAYYSVPDHVVVFPAGLLQPPFFHPGYPRAVNFGAVGSIMAHKLLHIF----FQFLLPG-GCPAC 580

  Fly   491 DRELDRNPRFQQELGCLRRRF-------------GRKRYEKFADASGLELAYSAYFDTAQTDHKR 542
            |..     ..|:.|.||..|:             .....|..||..|:.:|:.||         |
  Rat   581 DTR-----ALQEALLCLEHRYAAFPLPSMSSFNGSHTLLENAADIGGVAIAFQAY---------R 631

  Fly   543 NRSAE---ELVTQKQQ------FFHNFAQFFCSDKELLQ---AHDHGSDRKRVNDAVAHFEPFRE 595
            .|..|   ||....|:      ||.::||..|  :||:.   ...|...|.||:..:::...|.:
  Rat   632 KRITERTGELTLPNQELSPYQLFFRSYAQVMC--RELISQDPQDTHSPPRLRVHGPLSNSPDFAK 694

  Fly   596 AFSC------GPSPRRRQCRLY 611
            .|.|      .||.|   |:|:
  Rat   695 HFLCPSGSLLNPSTR---CKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:472708	147/725 (20%)
Kel	NP_001178540.1	M13	78..711	CDD:341056	150/733 (20%)