Protein Alignment frma and nep-21

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001360525.1
• Gene: nep-21 / 179925
• WormBaseID: WBGene00011794
• Length: 864
• Species: Caenorhabditis elegans
• Alignment Length: 761
• Identity: 142/761 - (18%)
• Similarity: 267/761 - (35%)
• Gaps: 237/761 - (31%)

  Fly    11 IVGLLVVQVKSHPQADPCQNFYKVACGNWSAS----------HATDSYESFMDRLDYNYQEKLAD 65
            :.|.|...:.|  :.:||::||:.||||:..:          |.....:|.:::       ::..
 Worm   181 LAGFLAENLNS--KINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNK-------QVKS 236

  Fly    66 LLDNEREDDEPHFLQQLRNFYTACRKPLSQDQV-------LRILEHLI----VMENIQNEELSVG 119
            :|.:....:|..:.:..:.:|..|   |.::::       :|.:...|    .:|..:.:|.|..
 Worm   237 MLQSPISANEKPWDKVAKGYYQKC---LDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHS 298

  Fly   120 LTAAFRLQVLIDLNDSNTYDIWKQLMSHRKHWDPNTTNREPLTREMFDKLWASLPKIPF------ 178
            ...  ::.::::|...|.. |.:..::|    ||:.::|..:  |:....|.:..:.|:
 Worm   299 WEE--QIALVLNLTGVNAV-ILEMAVTH----DPSNSSRSVI--ELDQPKWGAGSRYPYLSGAND 354

  Fly   179 PFKEYY---------------------WRELSELEEKIMSYGSEDDGFDSGDLVTRIP------- 215
            |....|                     ..|..|.|.|:::       |.:.|:|.|.|
 Worm   355 PMLRNYTTLMKMTAVALGADPAIAEKEMNEAMEFELKLVN-------FSADDMVRRDPERGNNRF 412

  Fly   216 PFWMM----PW------------------PNGNITYENLSQ---MAHWLDIKANEFILTYIYMRL 255
            ..|.:    |:                  ||..:....:..   :.|.|.......:..||..||
 Worm   413 ELWQLKSVFPFINFEKYLKTVFKELVALSPNHTVIVREIDYFVGIQHVLQSTPKRVLANYISWRL 477

  Fly   256 KLVAEGVSTESWHI-----------------------------DR-DQCAEQSRQILSHPAAWL- 289
               .:|..|..:..                             || :.|...|..::..|...|
 Worm   478 ---VQGGPTGDYFSFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLF 539

  Fly   290 VEKNHPRLKEEPVLQDIFAELKQRFGQKLLANRNNFTRSTQHFL--LGKLKRMRLRLSILPRNSS 352
            ||....:.:....:.::.:.||..|.::|            |.|  :.::.|.|
 Worm   540 VENFFEKERAMKKMTELTSYLKNEFIKQL------------HVLDWMDEITRRR----------- 581

  Fly   353 AQSMVRRIERH-------YRDVHMNAS--------DYFGNLHIGLNHSRSHKKYAQLWAIVFGRQ 402
            |.|....||..       :.|..|..:        :|.  ||:.:          ::..:.|..:
 Worm   582 AISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPREYL--LHLTI----------RVKLVRFTEE 634

  Fly   403 L--IPSRISKSDLY--PTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGF 463
            |  :...:.:|..:  |.||       .|:|....|.:|.|..:::.||.|.|.|:.:||..:|.
 Worm   635 LLRLDQPLDRSMWFQSPAQV-------DAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGA 692

  Fly   464 ILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELGCLRRRFGRKRY------------ 516
            ::|||:||.||.:|..:...|..:...|.|.:.  :|.::..|..|::.....
 Worm   693 VIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEE--KFIEKTRCFVRQYENVHVVEADIHLNGQLS 755

  Fly   517 --EKFADASGLELAYSAYFDTAQTDHKRNRSAEEL-----VTQKQQFFHNFAQFFCS---DKELL 571
              |..||..|::.|::||  .|...:....|...|     .|.:|.||..:|..:||   .|..:
 Worm   756 LGENIADNGGVKTAFNAY--KAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYI 818

  Fly   572 Q---AHDHGSDRKRVNDAVAHFEPFREAFSC---GPSPRRRQCRLY 611
            |   ...|...:.|....:.:...|.:||.|   .|....|:|:::
 Worm   819 QIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	136/735 (19%)
nep-21	NP_001360525.1	M13	193..862	CDD:341056	138/743 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910