Protein Alignment frma and nep-16

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001023203.2
• Gene: nep-16 / 177541
• WormBaseID: WBGene00018472
• Length: 868
• Species: Caenorhabditis elegans
• Alignment Length: 698
• Identity: 146/698 - (20%)
• Similarity: 242/698 - (34%)
• Gaps: 196/698 - (28%)

  Fly    24 QADPCQNFYKVACGNWSASHATDSYESFMDRLDYNYQEKLADLLDNEREDDE--PHFLQQLRNFY 86
            :.:||:|||:.:|..:. |...|...||:.:|......::..||.:| ||..  |...:..|:.|
 Worm   253 EIEPCENFYRYSCQRYH-SQTADKQMSFLSQLKDESLRRMHSLLSSE-EDSRLLPKSARLSRSLY 315

  Fly    87 TAC-----RKPLSQDQVLRILEHL---IVMENIQN-------EELSVGLT--AAFRLQVLIDLND 134
            :||     |...:...:|..:.:.   .::.:.||       .|...|:.  .|.|..:::...|
 Worm   316 SACMNAVLRSSNAPTDLLTFIRNFPCGPLLRDCQNFHADSYSWERHAGMLDWYAGRYNLIVYDRD 380

  Fly   135 SNTYDIWKQLMS-------------HRKHWD---PNTTNREPL----TREMFDKLWA--SLPKIP 177
            .:..|..|.::.             .|...|   |:.|..|||    .|:.....:|  ||.:.|
 Worm   381 VHPQDRSKIILQIKPPDLTPIVGLIERDLIDLARPSPTEFEPLLQLSLRQNLLSAFARDSLLRDP 445

  Fly   178 FPFKEYYWREL-SELEE--KIMSYGSEDDGFDSGDLVTRIPPFWMMPWPNGNITYENLSQMAHWL 239
                    |:: |:|:|  ::|.     |.:.|......:.|         |.||..:.:|..
 Worm   446 --------RDVQSQLDEVARLMV-----DLYISARQSASLTP---------NTTYMTIGEMFQ-- 486

  Fly   240 DIKANEFILTYIYMRLKLVAEGVSTESW------------HIDR--DQCAEQSRQILSH----PA 286
                   .|..:|:|..|.|:..:|..|            :..|  |..|:.|||.:::    ..
 Worm   487 -------ALPQLYLREFLDAQLSNTYRWTETDMLSIQDYDYFARLSDIMAQTSRQAVANYLLTVT 544

  Fly   287 AWLVEK--NHPR--------------------LKEEPVLQDIFAELKQRFGQKLLANRNNFTRST 329
            .|.:::  ..||                    :..:...|.|.....|.|.|.|..:..:..|||
 Worm   545 VWNLKQYSYSPRDQYGWRECVDQISSFEIGRKMYVDKASQTIDLPKIQEFLQNLKIDFLSVHRST 609

  Fly   330 QHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHIGLNHSRSHKKYAQL 394
            ....|..:.|:...:. .||....:.:   |.:....|.:|.:|||.::
 Worm   610 PLQYLSNINRLGFYVG-FPRRLQNEEL---IWKPVSQVSLNETDYFDSM---------------- 654

  Fly   395 WAIVFGRQLIPSRISKSDLYPTQVRGY-----GTY-----ASAFYIVKQNML--------IVPLS 441
                       .|:.|::      |.|     |||     .:.|.|....||        ::||:
 Worm   655 -----------IRVGKAE------RDYTMSQIGTYLDNDDTTTFPISDPTMLYNSNVGAIVIPLA 702

  Fly   442 LLEPPFYTHGQ--PSILTYSALGFILGHELS----HGFDSEGMTFSSHGVGSSAVDRELDRNPRF 500
            .:|||.|..|.  |....||:||......:|    .|.|..........|....:|....|:|..
 Worm   703 FIEPPIYLPGDEVPMYGIYSSLGITTLQMISKVFWQGLDKTSQLECLDNVFRGFLDANRQRSPNI 767

  Fly   501 QQELGCLRRRFGRKRYEKFADASGLEL-AYSAYFDTAQTDHKRNRSAEELVTQKQQFFHNFAQFF 564
            :.||         ....:.|||....| :|:.:.:.....|::...|.:.....:.....|:..|
 Worm   768 EPEL---------LATIELADAFKSALYSYAKWQNDHHIHHEKTLPAFDSTDSMRSLMLTFSTMF 823

  Fly   565 CSDKELLQAHDHGSD-RKRVNDAVAHFEPFREAFSCGPSPR---RRQC 608
            ||.    :..:.||| ...:|....:...|...|:|..|.|   ||.|
 Worm   824 CSG----EGSEPGSDYEAMINTVAENSRMFSIHFNCNNSSRLYNRRTC 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	141/685 (21%)
nep-16	NP_001023203.2	GluZincin	254..>725	CDD:387391	112/540 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010