Protein Alignment frma and nep-1

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_496490.2
• Gene: nep-1 / 174787
• WormBaseID: WBGene00013926
• Length: 754
• Species: Caenorhabditis elegans
• Alignment Length: 752
• Identity: 147/752 - (19%)
• Similarity: 253/752 - (33%)
• Gaps: 223/752 - (29%)

  Fly     6 RLLELIVGLLVVQVKSHPQADPCQNFYKVACGNWSASHA----TDSYESFMDRLDYNYQEKLADL 66
            |||:..:.|         ..|||.:|::.||..|..||.    ..||..|...     :||:...
 Worm    74 RLLQKSLNL---------SLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTAT-----REKVLAE 124

  Fly    67 LDNEREDD----EPHFLQQLRNFYTACRKPLSQDQV--LRILEHL-------------------- 105
            :....||:    ....:..::..|..|......:.|  ..:||.:
 Worm   125 MRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKWRESTFD 189

  Fly   106 ---IVMENIQNEELSV-------------------------GLTAAFRLQVLIDLNDSNTYDIWK 142
               ::...||:.::||                         ||..:.|...|    |...|:  |
 Worm   190 LTKLLSNTIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYL----DEKKYE--K 248

  Fly   143 QLMSHRKH-------------WDPNTTNREPLTREM--FDKLWASL----------PKIPFPFKE 182
            |:.::||:             ...|.:..|....|:  |:|.||.:          .|:
 Worm   249 QMKAYRKYTIGKVRYYTEDAGMAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKL------ 307

  Fly   183 YYWRELSELEEKIMSYGSEDDGFDSGDLVTRIPPFWMMPWPNGNIT-----YENLSQMAHWLDIK 242
            |..|...:|:| .||.      .|...|.....||.:..:...|.:     .|.|.:|...|...
 Worm   308 YNVRRFDDLKE-YMSI------IDWKKLTLSTTPFLVHSYLKTNPSIIISDVEYLQKMNTLLQNT 365

  Fly   243 ANEFILTYIYMRLKLVAEGVSTESW-------HIDRDQ------------------CAEQSRQIL 282
            ....:..||.:|.        ..||       :.|..|                  |...:...|
 Worm   366 DPRIVTNYILLRW--------AGSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKL 422

  Fly   283 SHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLLANRNNFTRSTQHFLLGKLKRMRLRLSIL 347
            |:.:..:..:.:.....:....|:..:|::.|...:.|| :.....|:.:.|.|
 Worm   423 SYASGSMYVRKYFDANAKNTTLDMITDLQEAFRNMMHAN-DWMDAETKKYALEK----------- 475

  Fly   348 PRNSSAQSMVRRIERHYRDVHMN---ASDYFGNLHIGLNHSRSHKKYAQL------WAIVFGRQL 403
                 |..|:::|  .|.|..:|   ..|::..|     .......::||      |...|..:.
 Worm   476 -----ADQMLKQI--GYPDFILNDEKLDDWYKGL-----EGAPEDSFSQLVEKSIQWRNNFYYRR 528

  Fly   404 IPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHE 468
            :...:::.:...:     ....:|||...:|.:..|..:|:.||:....|..|.|..:|.::|||
 Worm   529 LLEPVNRFEFISS-----AAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAVIGHE 588

  Fly   469 LSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELGCLRRRFGRKRY--------------EKF 519
            ::||||..|..|.:  ||:.....:...:.:|.:...|:..::...:.              |..
 Worm   589 ITHGFDDTGRQFDN--VGNLRDWWDNTTSSKFNERTQCIIEQYADVKLRGTDLRINGKLTQGENI 651

  Fly   520 ADASGLELAYSAYFDTAQTDHKRNRSAE----ELVTQKQQFFHNFAQFFCSDKE------LLQAH 574
            ||..|::.|:.||  .:..:....:.|.    |.:|.:|.||..:||.:|..|.      ||...
 Worm   652 ADNGGIKQAFKAY--KSYLEKHGGQEARLPQFESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTD 714

  Fly   575 DHGSDRKRVNDAVAHFEPFREAFSC---GPSPRRRQC 608
            .|..:..|||..:.:...|.|||.|   .|....::|
 Worm   715 PHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRC 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	141/724 (19%)
nep-1	NP_496490.2	PepO	80..754	CDD:226118	144/746 (19%)
		M13	85..751	CDD:189000	142/730 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010