Protein Alignment frma and nep-26

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001022540.1
• Gene: nep-26 / 174593
• WormBaseID: WBGene00014171
• Length: 807
• Species: Caenorhabditis elegans
• Alignment Length: 717
• Identity: 156/717 - (21%)
• Similarity: 256/717 - (35%)
• Gaps: 192/717 - (26%)

  Fly    26 DPCQNFYKVACGNW---SASHATDS----YESFMDRLDYNYQ--EKLAD----LLDNEREDDEPH 77
            :||.|||:.|||.|   |.:...||    ||:.....|...|  .|:.|    |..|..|
 Worm   125 EPCDNFYQFACGGWINQSVNLKYDSWNTLYETQRTAHDQIVQAMHKINDGSYPLPTNAGE----- 184

  Fly    78 FLQQLRNFYTACRKPLSQDQV-LRILEHLI-----VMENIQNEELSVGLTAAFRLQVLIDLNDSN 136
              :.....|..|....:.:|. |.:.|..:     .|..::|..|.  ...:|.:::..|.....
 Worm   185 --RAAAKMYEQCMDTDTLEQTGLHLWERFVDELGGWMPELKNGALE--QEESFEIELDEDEKKRR 245

  Fly   137 TYDIWKQLMSHRKH------W---DPNTTNREPLTREMFDKLWASLPKIPFPFKEYYWRELSELE 192
            .::|...::|...:      |   :.|..|    ::|....::..||.:..|.|.:|.:||:
 Worm   246 RFEIEDIILSAFNYSVFPLFWAGVEVNYLN----SKEHLITIYEQLPILLAPEKYHYNKELT--- 303

  Fly   193 EKIMSYGSEDD------------------GFDSGDLVTRIPPFWMMPWPNGNITYENLSQMAHWL 239
             ..|.||..:.                  ||||.|...|     ||        ..|:..:.:.:
 Worm   304 -PEMIYGKMEGPPVTRALQQVGEELSAVLGFDSTDEKVR-----MM--------IANMIYLEYQI 354

  Fly   240 DIKANEFIL----TYIYMRLKLVAEGVSTESWHIDRDQCAEQSRQILSH--PAA------WLVEK 292
            .:..:.|..    .|..:.|:.:.|.....:||....:...::   |||  |.|      |:
 Worm   355 TMAGSTFYKEKKERYTVVMLRELQEIAPAINWHYFLSRLVGEN---LSHSEPIALKTGTQWI--- 413

  Fly   293 NHPRLKEEPVLQDIFAELKQ-RFGQKLLAN------------------RNNFTRSTQHFLLGKLK 338
                    |:|..|..:||| |.|..:|.|                  |:...........|...
 Worm   414 --------PILSAIVEKLKQSRSGVAVLKNYVKWKTIMFHLAYASPKCRDGLLWMAVSLYSGAAS 470

  Fly   339 RMR----LRLS-ILP-----------------RNSSA-QSMVRRIERHY------------RDVH 368
            :.:    |||| |.|                 :|..| |::..||:..|            |:..
 Worm   471 QRKEFCVLRLSGIFPLSLPSILRKIDGIDHTEKNVKAVQNIADRIQEKYEEMVRSSNLFSDRETR 535

  Fly   369 MNASDYFGNL--HIGL-NHSRS----HKKYAQL-----WAIVFGRQLI-PSRISKSDLYPTQVRG 420
            .|..|...|:  .||. :..||    .|:..:|     |::|.|...: ..|:.:..| |...|.
 Worm   536 ENVIDKVNNMTKFIGFPDAMRSDYEMEKEAVRLHDTLFWSMVLGSSSVYKERLQRLRL-PVDPRS 599

  Fly   421 YGTYASAFYI----VKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFS 481
            :.....|..:    .::|::.:|...|..|:....|.....|:.:|.|:||||:|.||.:|   .
 Worm   600 WVDTRPAISVPAHNYERNLVQIPFDSLRLPYADEHQLDFANYAGIGTIIGHELTHAFDGQG---K 661

  Fly   482 SHG-VGSSAVDRELDRNPRFQQELGCLRRRFG------------RKRYEKFADASGLELAYSAYF 533
            .|| .|:..|....|....|:....|..:::.            ...||..||..||::||.|:.
 Worm   662 LHGPTGNLGVWWSTDSIREFKAREQCFVKQYAGLMDSHDMNAAKEGLYENIADQVGLKVAYEAWK 726

  Fly   534 DTAQTDHKRNRSAEELVTQKQQFFHNFAQFFCS-DKELLQAHDHGSDRKRVNDAVAHFEPFREAF 597
            .....:..|....|: .:|.|.||..:.|.:|: ..:..:...|..:|.|:..::.:...|..|:
 Worm   727 SNGNQNSGRMPGLEK-YSQDQLFFLAYTQGWCALRSKSYKLQPHMEERIRMLGSLQNSPEFASAW 790

  Fly   598 SC 599
            .|
 Worm   791 KC 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	156/717 (22%)
nep-26	NP_001022540.1	PepO	111..807	CDD:226118	156/717 (22%)
		M13	124..805	CDD:189000	156/717 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010