Protein Alignment frma and nep-3

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 669
• Identity: 131/669 - (19%)
• Similarity: 238/669 - (35%)
• Gaps: 194/669 - (28%)

  Fly    23 PQADPCQNFYKVACGNWSASHATD-----SYESFMDRLDYNYQEKLADLLDNEREDDEPHFLQQL 82
            |..|||:|||:.|||.::..:..|     ..:..:.||..::..|      |:....:..  ..:
 Worm    80 PSVDPCENFYQAACGKYNEHNVIDGSRTAQKQQIVKRLIRDFLHK------NQSSTSKSE--NSM 136

  Fly    83 RNFYTACRKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRLQVLIDLNDSNTYDIWKQLMSH 147
            :..|..|:    :.:.:::|.:..:::.|......:|                    .|..|
 Worm   137 KLLYEKCK----EAKTIKVLGNQNLLQEIFMNIQKIG--------------------SWPVL--- 174

  Fly   148 RKHWDPNTTNREPLTREMFDKLWASLPKIPFPFKEYYWRELSELEEKIMSYGSEDDGF----DSG 208
            .::||....|                              |:|:...::..|..:.||    .|.
 Worm   175 DENWDGKKFN------------------------------LNEMLLSLIRLGVSNFGFFEIIISS 209

  Fly   209 DLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIKANEFI-------LTYIYMRLKLVAEGVSTES 266
            |....|.|....|      |.||||      ||.:..|:       :|.|...|: ..|.:..|.
 Worm   210 DAFVEIKPARNFP------TRENLS------DIISKVFLGNGFQPNITAIENDLR-EYENLQREL 261

  Fly   267 WHIDRDQCAEQSRQILSH------PAAWLVEKNHPRLKEEPVLQDIFAELKQR-FGQKLLANRNN 324
            ..::|......:|.::::      .:..|..|..|..:.|.|:.|.......| |.|..|...|
 Worm   262 KSLERLIQTTPNRSLVNYLIFNYLKSVMLEYKRLPEEQCEGVVIDFLPRASTRVFVQNFLDKEN- 325

  Fly   325 FTRSTQHFLLGKLKRMRLRLSILPRNS----------------SAQSMV---------RRIERHY 364
                 :.::.|.::.:::....:.:.|                :.:||:         ..::|.:
 Worm   326 -----RKYVAGMIEDVKMGFIDMIQESTWLNEESKKVAVQKVKNIKSMIGYPDFFEPPGTLDRSF 385

  Fly   365 RDVHMNASDYFGNLHIGLNHSRSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFY 429
            :|:::..:|.:..:      .|..:|:.....:.|....||       |.|.|..   .:|:|||
 Worm   386 KDLNIEQTDSYHTI------VRKIQKFTNEQCMEFVASEIP-------LDPRQPI---LHANAFY 434

  Fly   430 IVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDREL 494
             ...|.|.:...:|:.|.:....|..:..:.:|.:|.||:.|.||..|:.:...|      .:.:
 Worm   435 -QNTNFLAILAPVLDDPIFDTTFPRYVNLAVIGNVLAHEIGHAFDHTGINYDDAG------QQRI 492

  Fly   495 DRNPRFQQELG----CLRRR--------FGRK------RYEKFADASGLELAYSAYFDTAQTDHK 541
            ...|...:|.|    ||.|:        |||.      .:|..||..|:|.|:       :|..|
 Worm   493 WLTPEDSEEYGKRLRCLLRQHDEYDDPDFGRNLNGSKTLHEISADRFGVEAAW-------RTFKK 550

  Fly   542 RNRSAEELVTQKQQF------FHNFAQFFC-----SDKELLQAHDHGSDRKRVNDAVAHFEPFRE 595
            .:.|.|..:...|.|      |...|..:|     :|.:.....:|.::..|||...|:...|.|
 Worm   551 LDLSNESEIVGFQNFNIDQLYFRTAALIWCRQRDTTDLQYALQREHPTNNFRVNGIYANMPQFAE 615

  Fly   596 AFSC---GPSPRRRQCRLY 611
            .|:|   .|...:::|.|:
 Worm   616 TFNCPLGSPMNPKKKCDLF 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	127/655 (19%)
nep-3	NP_494679.2	M13	82..631	CDD:189000	128/662 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010