Protein Alignment frma and nep-13

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001342017.1
• Gene: nep-13 / 173672
• WormBaseID: WBGene00018196
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 747
• Identity: 141/747 - (18%)
• Similarity: 263/747 - (35%)
• Gaps: 230/747 - (30%)

  Fly     5 LRLLELIVGLLVV--QVKSHPQA---------------------------------DPCQNFYKV 34
            |.::.:.:|.::|  ::.|.|||                                 |||::||:.
 Worm    49 LVIIAICMGAVIVFWRMDSAPQAICKTDHNKTRDVCKTAECITLSSTLLNWQNTNIDPCEDFYEY 113

  Fly    35 ACGNWSASHATDS-----------------------------------YE--SFMDRLDYNYQEK 62
            :||.:......|.                                   ||  |...|::..:||.
 Worm   114 SCGRYQEHTLNDGIRANEKDTIVMKLIRQFVLKNQSTTSNSENALMLLYEKCSLRYRMENRHQET 178

  Fly    63 ---LADLLDN----------EREDDEPHF--LQQLRNFYTACRKP--LSQDQVLRI------LEH 104
               ..::.:|          ::..:..||  ...|.|..:....|  |.:.:|:.:      .:.
 Worm   179 EVIQREVFENIRKIGSWPIADKNWNSSHFNLNNMLSNMASIHMLPFGLFETRVIELYPMNTTAKQ 243

  Fly   105 LIVME-----NIQNEE--------LSV-GLTAAFRLQVLIDLNDSNTYDIWKQLMSHRKHWDPNT 155
            |::..     :|..||        ||| |:|:..: :|..|:.:|...|  |::  ...|.||..
 Worm   244 LVIRPTKLKFSIPQEELVRAIRDLLSVNGITSIMK-KVKEDVAESFALD--KEI--GNIHIDPQP 303

  Fly   156 TNREPLTREMFDKLWASLPKIPFP--FKEYY------WRELSELEEKIMS------YGSEDDGFD 206
               :|.|   ..:|..::|.|.|.  .|.|.      |   |.|..||.|      :|..:   :
 Worm   304 ---KPAT---LSELQKAVPDIDFERIIKSYLNPKTGNW---SSLRTKIFSARFELFFGKNN---N 356

  Fly   207 SGDLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIKANEFILTYIYMRLKLVAEGVSTESWHIDR 271
            ...::.|..|                ..:|::|.:|..|:...:.:...|:.:          |.
 Worm   357 LSSIIARTKP----------------RILANYLFLKYIEYAYFFFFDNTKVFS----------DD 395

  Fly   272 DQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLLANRNNFT---RSTQHFL 333
            |.|.|.....|...:..:..:||.:.:...|..:|...:|..:.:.:    ||.|   .||:...
 Worm   396 DFCTEVVTTSLPRASLRVFVRNHFKKENMAVASEIVEVVKTAYVEII----NNSTWLHNSTRESA 456

  Fly   334 LGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHIGLNHSRSHKKYAQLWAIV 398
            :.|:.:|:..:..    :........::..:..:.::.||.|..|...:|..    |..||...|
 Worm   457 IEKVVKMKKVIGY----TEEYERTGALDEMFETLQLSRSDSFFVLMTKVNRF----KIEQLMDFV 513

  Fly   399 FGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGF 463
            ....|:      :.:.|.      ..|:|||...:|:|.|.:..|:.|.:....|..:..:.:|.
 Worm   514 SSDSLL------NPIEPL------VMANAFYFPTKNLLNVLVPFLDKPLFDFKYPRYVAMAGVGR 566

  Fly   464 ILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNPRFQQELGCLRRRF---------GRKR---- 515
            :|.||:.|.||..|......|.......||  ....:.:...|...:|         |::.
 Worm   567 VLAHEIGHAFDINGRQTDEIGRTRDWWTRE--DTEEYDRRSECFAEQFTNFKDPSFKGKQNGTEV 629

  Fly   516 -YEKFADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHNFAQF--------FCSDKELL 571
             .|..|||.|:|.::.|:       .|.|.:.|:.:.|.:.  |:|.:.        ||:...:.
 Worm   630 LAEIIADALGMEASWIAF-------KKINLTEEQGLIQFED--HDFGKLYFQVAALDFCAPSRIE 685

  Fly   572 QAH----DHGSDRKRVNDAVAHFEPFREAFSC 599
            :.:    .|.:::.|:|.|.::...|.:.:.|
 Worm   686 ERYSDQLSHPTNKFRINGAFSNSRAFADTYKC 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	135/725 (19%)
nep-13	NP_001342017.1	M13	104..729	CDD:189000	134/692 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010