Protein Alignment frma and Nep4

DIOPT Version :10

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_061501026.1
• Gene: Nep4 / 1273777
• VectorBaseID: AGAMI1_013990
• Length: 1007
• Species: Anopheles gambiae
• Alignment Length: 791
• Identity: 166/791 - (20%)
• Similarity: 277/791 - (35%)
• Gaps: 271/791 - (34%)

  Fly    23 PQADPCQNFYKVACGNWSASH-------ATDSYESFMDRLDYNYQEKL-----ADLLDNEREDDE 75
            |.||||.:||:.|||||...:       |.|::|...:.||...::.|     |.|||.|
Mosquito   259 PDADPCDDFYQYACGNWDRVNPIPKDKAALDTFELLRESLDLVLKQLLLEGEPAGLLDVE----- 318

  Fly    76 PHFLQQLRNFYTACRKPLS--------------------QDQVLRI---------------LEHL 105
             :.|..:|:.....:|..|                    |.|:.|:               :::.
Mosquito   319 -NALSTVRSQPDGTKKSTSTTTTAASAGWPTTTVTGGPAQQQLHRVRKRGRAENRNRSGRAVQNK 382

  Fly   106 IVMENIQ------NEELSVGLTAAFRLQVLI------DLNDSNTYDIWKQLMSHRKHW---DPNT 155
            :::.:.|      ..||.:...|..:.:.|.      :|.:....:..:.|:.....|   :|:|
Mosquito   383 LIIRSAQVKRVRRKRELLINDDAEMKARHLFVSCMNYELIERRGLEPLRTLLHSLGGWPVLEPHT 447

  Fly   156 TNREPLTREMFDKLWASLPKIPFPFK------EYYWRELSELEEKIMSYGSEDDGFDSGDLVTRI 214
            .:     ...||  |.:|......:.      |:...::...:|.|:.:.....|..:.|
Mosquito   448 WD-----ESSFD--WLNLTAALRRYNNDVLIVEWVGPDIKNSDENIVQFDQTSLGLPTRD----- 500

  Fly   215 PPFWMMPWPNGNITY-----ENLSQMAHWLDIKA-------NEFI------------------LT 249
              :::.|   ||..|     :.:.::...||:.|       :|.|                  ::
Mosquito   501 --YYLQP---GNRKYLEAYRQFMLEVIGLLDVPADTARQATDEMIEFETQLANITSTPEERNNVS 560

  Fly   250 YIYMRLKL--VAEGVSTESW-H---IDRDQCAEQSRQILSHPAAW------LVEKNHPRLKEEPV 302
            .:|.:|.|  :.|.|...:| |   |..::....|..::....::      |:::..||:....:
Mosquito   561 TLYRKLMLDQLQEEVPQINWTHYLTIVTERPVNGSSFVVMFAMSYMRDLVELIDQTEPRIVANYL 625

  Fly   303 -----------LQDIFAELKQRFGQKLLANRNN----------------------FTR------- 327
                       |.|.|...||||...|.....|                      |.|
Mosquito   626 LWRFVRHRINNLDDRFLGAKQRFSNALFGRERNPPRWKNCVTQVNANMGMAVGAMFVRRYFDENS 690

  Fly   328 ---------------------------STQHFLLGKLKRMRLRLS----IL-PRNSSAQSMVRRI 360
                                       :|:.....|:..|.||:.    || |...||:
Mosquito   691 KRDTLTMTHELQDAFREILGRTGWIDMATRQLAEQKVNAMSLRIGYPDFILDPEQLSAR------ 749

  Fly   361 ERHYRDVHMNASDYFGNLHIGLNHSR--SHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGT 423
               |..:.::...||.|....|:|.|  ..:|..|                     |.....:.|
Mosquito   750 ---YATLEIHPDRYFENTLNVLSHIRRTDQEKLGQ---------------------PVNKTAWHT 790

  Fly   424 ---YASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHG- 484
               ..:|:|...:|.::.|..:|:||||....|..:.|..:|.::||||:||||.:|..|...|
Mosquito   791 APAVVNAYYSRNKNQIMFPAGILQPPFYHRHLPKAINYGGIGVVIGHELTHGFDDKGRLFDRDGN 855

  Fly   485 VGSSAVDRELDRNPRFQQELGCLRRRFGRKRY--------------EKFADASGLELAYSAY--F 533
            :.....||.::   .|.:...||..::||.|.              |..||..|::.|:.||  :
Mosquito   856 LYRWWSDRAIE---EFHERAACLVEQYGRYRIAEVDVQLDGENTQGENIADNGGIKQAFLAYSKW 917

  Fly   534 DTAQTDHKRNRSAEEL----VTQKQQFFHNFAQFFC------SDKELLQAHDHGSDRKRVNDAVA 588
            ..|||| :|...||.|    ||:.|.||.||||.:|      :.:..|:...|...|.||...::
Mosquito   918 LAAQTD-RRVLEAETLPGLNVTRTQLFFLNFAQIWCGAMRPEATRNKLKTAVHSPGRFRVIGTLS 981

  Fly   589 HFEPFREAFSC 599
            :.|.|...:.|
Mosquito   982 NSEDFAREYHC 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:472708	165/789 (21%)
Nep4	XP_061501026.1	None