Protein Alignment frma and Nep5

DIOPT Version :10

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_061503273.1
• Gene: Nep5 / 1273520
• VectorBaseID: AGAMI1_014349
• Length: 834
• Species: Anopheles gambiae
• Alignment Length: 789
• Identity: 154/789 - (19%)
• Similarity: 261/789 - (33%)
• Gaps: 264/789 - (33%)

  Fly    26 DPCQNFYKVACGNWSASH-ATDSYESFMDRLDYNYQEKLADLLDNEREDDEPHFLQ--------- 80
            |||::||:.|||||...| ..|:|.||    |: :.|:.|.:|.|.|     |:||
Mosquito   107 DPCEDFYQYACGNWEDEHPRPDTYVSF----DW-FSERQAKILRNIR-----HYLQANSSALDPK 161

  Fly    81 ---QLRNFYTACRKPLSQDQ--------------------VLRILE----------------HLI 106
               |.|..|.||....:.|:                    :|.:.|                .|.
Mosquito   162 PVVQARTMYAACLNLTAMDRLGYGPVFKYLKQFQLPPYPSLLNVTEGPASATFQGYGFDWVKSLA 226

  Fly   107 VMENIQNEELSVGLTA-----------------------AFRLQVLIDLNDSNTYDIWKQLMSHR 148
            .::.:...::.:||..                       .|...:|..:....|..  |.::|..
Mosquito   227 KIKQLLGMDIFIGLDVYPDPRHRDYNRLVLGTPESGSDLPFNTDILRHIRRGRTRR--KLMVSAD 289

  Fly   149 KHWDPNTTNRE---------PLTR----------------------EMFDKLWASLPKIPFPFKE 182
            ...|..:...|         |||.                      |.|:..:.....|...|.:
Mosquito   290 DEADGESDGEEVEDADDEVGPLTAYKKFMIGVMKLLVNSTDPTIKVESFNAQFERAATIVVQFSD 354

  Fly   183 YYWRELSELEEKIMSYGSED---------------DGFDSGDLVTRIP-PFW------------- 218
            ...:...|.|....|...||               .......|..:.| |.|
Mosquito   355 SISKFNREAENASRSTNVEDRLNLQDIVYYTVADLQNITDTHLAPKDPLPIWERLLASVFEGIPE 419

  Fly   219 --------MMPWPNGNITYENL-------SQMAH-----WLDIKANEFI---------LTYIYMR 254
                    ::...|.::.|..|       :.:||     |..: ..|.|         |.|.|.:
Mosquito   420 AQLNLQDELILTSNADLLYLKLLVDYLAVTPLAHIELYIWWTV-VEELILHTTLEVRKLYYDYYK 483

  Fly   255 LKLVAEGVSTESWHIDRDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLL 319
            ....::|.|:.:.:     |.....::|....::.:..::.....:|.:||:...::..| :.|:
Mosquito   484 SIAPSDGFSSRTLY-----CTGTVNRLLGMAVSYAISSDNFTRDTKPRVQDMLRYIRTAF-EGLV 542

  Fly   320 ANRNNFTRSTQHFLLGKLKRMRLRLS----ILPRNSSAQSMVRRIERHYRDVHMNASDYFGNLHI 380
            .:.......|:...|.|.:.||..:.    ||..        |.:|:||..:.:|.|.:..|:..
Mosquito   543 RDTTWMDWPTKQSTLRKSQAMRSLIGFPDWILDH--------RELEQHYSGLQVNESTHLENMMQ 599

  Fly   381 GLNHS------RSHKKYAQLWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVP 439
            .:...      |..:|:...|                :..||.|       :||:..::|.:.:|
Mosquito   600 EVQRKNIIKLRRWRQKHELSW----------------ETLPTNV-------NAFHTFQENAITIP 641

  Fly   440 LSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHG-VGSSAVDRELDRNPRFQQE 503
            :::|:.|||..|..: |.|.|||.||||||:||||..|..|...| :.....||.:.   .:...
Mosquito   642 IAILQYPFYHLGLEA-LNYGALGTILGHELTHGFDDSGRQFDKDGNLAQWWTDRTVQ---EYVNR 702

  Fly   504 LGCLRRRFGRKRY----------------EKFADASGLELAYSAYFDTAQTDHKRNRSAEELV-- 550
            ..|...::  .||                |..||..|:..|:.||     ..:.:|...:.|:
Mosquito   703 TKCFVSQY--SRYYIPEADDYIDGLLTLGENIADNGGVREAFRAY-----QLYVKNGGKDPLLPG 760

  Fly   551 ----TQKQQFFHNFAQFFCSDKELLQA-----HDHGSDRKRVNDAVAHFEPFREAFSCGP----S 602
                |.:|.||.::...:|.......|     ..|...:.|:...:.:...|.:.|.|.|    :
Mosquito   761 FEHYTHEQLFFISYGNIWCESHTQAAAKAYLDDSHCPGKFRLKGVLTNSPEFSQTFGCKPGTEMN 825

  Fly   603 PRRRQCRLY 611
            |.:.:||::
Mosquito   826 PGKDKCRIW 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:472708	150/773 (19%)
Nep5	XP_061503273.1	None