Protein Alignment frma and Ece2

DIOPT Version :9

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_647454.2
• Gene: Ece2 / 107522
• MGIID: 1101356
• Length: 763
• Species: Mus musculus
• Alignment Length: 696
• Identity: 143/696 - (20%)
• Similarity: 245/696 - (35%)
• Gaps: 184/696 - (26%)

  Fly    27 PCQNFYKVACGNW----SASHATDSYESFMDRLDYNYQEKLADLLDNEREDDEPHFLQQLRNFYT 87
            |||:||:.:||.|    ...:....:.:|....|.| |..|..||:|...:......::.|:||.
Mouse   114 PCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQN-QAILKHLLENTTFNSSSEAERKTRSFYL 177

  Fly    88 ACRKPLSQDQVLRI----LEHLI----------------VMENIQNEELSVGLTAAFRLQVLIDL 132
            :|   |..:::.::    |..||                .|:.::....:...|..|.:.|..|.
Mouse   178 SC---LQSERIEKLGAKPLRDLIDKIGGWNITGPWDEDSFMDVLKAVAGTYRATPFFTVYVSADS 239

  Fly   133 NDSNT----YDIWKQLMSHRKHWDPNTTNREPL--------------------TREMFD---KLW 170
            ..||:    .|.....:..|.::...|.|.:.|                    |||...   :|.
Mouse   240 KSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELE 304

  Fly   171 ASLPKIPFP-------FKEYYWRELSELE------------------------EKIMSYGSEDDG 204
            ..|..|..|       .|.|:...:|||:                        |.::.||:|
Mouse   305 IQLANITVPQDQRRDEEKIYHKMSISELQALAPAVDWLEFLSFLLSPLELGDSEPVVVYGTE--- 366

  Fly   205 F--DSGDLVTRIPPFWMMPWPNGNITYENLSQMAHWLDIKANEFILTYIYMRLKLVAEGVSTESW 267
            :  ...:|:.|..|..:..:...|:..:..|.:....: .|.|.:|..:|...|     ..|..|
Mouse   367 YLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDQRFE-TAQEKLLETLYGTKK-----SCTPRW 425

  Fly   268 HIDRDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLLANRNNFTRSTQHF 332
                ..|...:...|......|..|.....:.:.:.:.:..|::..|.:
Mouse   426 ----QTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEE---------------- 470

  Fly   333 LLGKLKRM--RLRLSILPRNSSAQSMV---------RRIERHYRDVHMNASDYFGNLHIGLNHSR 386
            .||.|..|  :.||:...:..:...|:         :.::..|....::...:|.|:....|.|
Mouse   471 TLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFS- 534

  Fly   387 SHKKYAQLWAIVFGRQL--IPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPFYT 449
                     |.|...||  .||| .:..:.|..|       :|:|:..:|.::.|..:|:.|||.
Mouse   535 ---------AKVMADQLRKPPSR-DQWSMTPQTV-------NAYYLPTKNEIVFPAGILQAPFYA 582

  Fly   450 HGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNP--------RFQQELGC 506
            |..|..|.:..:|.::||||:|.||.:|..:          |:|.:..|        .||....|
Mouse   583 HNHPKALNFGGIGVVMGHELTHAFDDQGREY----------DKEGNLRPWWQNESLTAFQNHTAC 637

  Fly   507 LRRRFGRKRY------------EKFADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHN 559
            :..::.:.:.            |..||..||:.||:||....:...:........:|..|.||..
Mouse   638 MEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVG 702

  Fly   560 FAQFFCSDKELLQAHD------HGSDRKRVNDAVAHFEPFREAFSC 599
            |||.:||.:....:|:      |...|.||...:::...|...|.|
Mouse   703 FAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGC 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:301352	143/696 (21%)
Ece2	NP_647454.2	M13	112..761	CDD:189000	143/696 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010