Protein Alignment frma and ecel1

DIOPT Version :10

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_012818808.2
• Gene: ecel1 / 100496473
• XenbaseID: XB-GENE-989944
• Length: 764
• Species: Xenopus tropicalis
• Alignment Length: 717
• Identity: 155/717 - (21%)
• Similarity: 249/717 - (34%)
• Gaps: 211/717 - (29%)

  Fly    23 PQADPCQNFYKVACGNWSASHATDSYESFMDRLDYNYQEKLADLLDNEREDDEPHFLQQLRNFYT 87
            |...||.:||..|||.|...|....     |:|.|.   .:|.:.:...|..|...||.:|..:
 Frog   111 PTISPCTDFYSFACGGWLRRHGIPE-----DKLIYG---TIAAIGEQNEEKLEHLLLQPVRRKH- 166

  Fly    88 ACRKPLSQDQVLRILEHLIVMENIQNEELSVGLTAAFRLQVLIDLNDSNTYDIWKQLMSHRKHWD 152
               |..::.:|....:..:.|.:|..      |.|...|||:.|...      |......|..||
 Frog   167 ---KGSAERKVKEFFKSCLNMRDIDR------LGARPMLQVIEDCGG------WDLPEDPRTQWD 216

  Fly   153 PN------------------TTNREPLTREMF----DKLWASLP-------------KIPFPFKE 182
            .|                  |.:.:......:    |:...:||             |:...:|.
 Frog   217 FNELLYKTQGVYSTAVFFSMTVSLDDKNSSRYIIRIDQDGLTLPERTLYLGQDEESIKVLEAYKV 281

  Fly   183 YYW---------------RELSELEEKIMSYGSEDDGFDSGDLVTRIPPFWMMPWPNGNITYENL 232
            :..               .|:..||:.:.:....:  ||  |:...|...:      ..:|...|
 Frog   282 FMQTILSLLGVENVQKKAEEILHLEQHLSNITISE--FD--DMRRDISTMY------NKVTLAQL 336

  Fly   233 SQMA---HWLDI------------------------KANEFILT--------YIYMRLKLV-AEG 261
            .|:.   :|.::                        |.:|.|.:        |:..|:.:| :|.
 Frog   337 QQITPHLNWKNLLNRIFHTNFPEDEEVVVLATDYMQKVSEMIRSTPASVLHNYMLWRIVVVLSEH 401

  Fly   262 VSTESWHIDRDQCAEQSRQI--------LSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKL 318
            :||..    ||...|.|:::        |:........|:.........:::.|:...:...|:|
 Frog   402 LSTPF----RDAIHELSKEMEGSEKQAELTKVCLTQANKHFGMALGALFVEEYFSSSSKAKVQQL 462

  Fly   319 LANRNN-----------FTRSTQHFLLGKLKRMRLRLSILPRNSSAQSMVRRIERHYRDVHMNAS 372
            :.|..:           ....|:.....|||.|.:.:.........:||    ::.| :..:|..
 Frog   463 VENIKHILDYRLEELDWMDTETKQAAREKLKHMMVMIGYPDVLLQPESM----DKEY-EFEVNEK 522

  Fly   373 DYFGNLHIGLNHSRSHKKYAQLWAIVFGRQLIPSRISKSD-LYPTQVRGYGTYASAFYIVKQNML 436
            .||.|:   ||..|        ::|....:.|...:.||. |.|.|.      .:|:|:..:|.:
 Frog   523 TYFKNI---LNSIR--------YSIKMAVRRIRQEVDKSAWLLPPQA------LNAYYLPNKNQM 570

  Fly   437 IVPLSLLEPPFYTHGQPSILTYSALGFILGHELSHGFDSEGMTFSSHGVGSSAVDRELDRNP--- 498
            :.|..:|:|..|....|..|.|..:|.|:||||:||:|..|..:.::|            ||
 Frog   571 VFPAGILQPTLYDPDFPQSLNYGGIGTIIGHELTHGYDDWGGQYDANG------------NPIQW 623

  Fly   499 -------RFQQELGCL-----------RRRFGRKRY-EKFADASGLELAYSAYFDTAQTDHKRNR 544
                   :|.::..|:           :|..||... |..||..||:|||.||....: |:...|
 Frog   624 WTEDSYSKFLKKAECIVDLYENFTVYNQRVNGRTTLGENIADLGGLKLAYYAYQKWVR-DNGPER 687

  Fly   545 SAEEL-VTQKQQFFHNFAQFFC----SDKELLQ--AHDHGSDRKRVNDAVAHFEPFREAFSCGPS 602
            ....| .|..|.||..|||.:|    |....||  ...|..:..||..:|:.||.|...|.|
 Frog   688 PLPRLKYTHDQLFFIAFAQNWCIKRRSQSIYLQVLTDKHAPEHYRVMGSVSQFEEFGRVFHC--- 749

  Fly   603 PR 604
            ||
 Frog   750 PR 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:472708	152/710 (21%)
ecel1	XP_012818808.2	M13	113..762	CDD:341056	154/715 (22%)