Protein Alignment frma and ece2

DIOPT Version :10

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_002935189.1
• Gene: ece2 / 100488407
• XenbaseID: XB-GENE-1011916
• Length: 766
• Species: Xenopus tropicalis
• Alignment Length: 694
• Identity: 142/694 - (20%)
• Similarity: 251/694 - (36%)
• Gaps: 178/694 - (25%)

  Fly    26 DPCQNFYKVACGNWSASH----ATDSYESFMDRLDYNYQEKLADLLDNEREDDEPHFLQQLRNFY 86
            ||||:||:.:||.|...:    ....:.:|....|.| |..|..:|:|...:.......:.:.||
 Frog   116 DPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQN-QAILKHILENATFNSSSEAEMKTQRFY 179

  Fly    87 TACRK-----PLSQDQVLRILEHL---IVMENIQNEE-LSVGLTAA--------FRLQVLIDLND 134
            .:|.|     .|.|..:..::|.:   .:..|.:.|. :||..|.:        |.:.|..|...
 Frog   180 LSCLKEQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKS 244

  Fly   135 SNT----YDIWKQLMSHRKHWDPNTTNREPLTREM--------------------------FDKL 169
            ||:    .|.....:..|.::...|.|.:.|...:                          |:.|
 Frog   245 SNSNIIQVDQSGLFLPSRDYYLNKTANGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETL 309

  Fly   170 WASLPKIP-------------------------FPFKEYYWRELSELE----EKIMSYGSEDDGF 205
            .|:| .:|                         |.:.:|....||.|:    |.::.||.|   :
 Frog   310 LANL-TVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYLTFALSPLDLNDTEPVVVYGKE---Y 370

  Fly   206 --DSGDLVTRIPPFWMMPWPNGNITYENLSQMAHWLDI---KANEFILTYIYMRLKLVAEGVSTE 265
              ...:||....|..:    |..:.:..:.:|:..||.   ||.:.:|..:|     .|:...|.
 Frog   371 LQQVSELVNNTDPMLL----NNYLVWNLVQKMSSSLDSRFEKAQDKLLESLY-----GAKKSCTP 426

  Fly   266 SWHIDRDQCAEQSRQILSHPAAWLVEKNHPRLKEEPVLQDIFAELKQRFGQKLLANRNNFTRSTQ 330
            .|    ..|...:...|......|..|:......:.:.:.:.:|::..|
 Frog   427 RW----QTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAF---------------- 471

  Fly   331 HFLLGKLKRM--RLRLSILPRNSSAQSMV---------RRIERHYRDVHMNASDYFGNLHIGLNH 384
            ...||.|..|  :.|.:...:..:...|:         :.::..|....::...:|.|:....|.
 Frog   472 ELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNF 536

  Fly   385 SRSHKKYAQLWAIVFGRQL-IPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPFY 448
            |      |:|.|    .|| .|....:..:.|..|       :|:|:..:|.::.|..:|:.|||
 Frog   537 S------AKLMA----EQLRKPPNREQWSMTPQTV-------NAYYLPNKNEIVFPAGILQAPFY 584

  Fly   449 THGQPSILTYSALGFILGHELSHGFDSEGMTFSSHG-----VGSSAVDRELDRNPRFQQELGCLR 508
            ....|..|.:..:|.::||||:|.||.:|..:...|     ..:|:::       .|:....|:.
 Frog   585 APTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLE-------AFKNRTECMV 642

  Fly   509 RRF-----------GRKRY-EKFADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHNFA 561
            .::           ||:.. |..||..||:.||.||........:..:.....:|..|.||..||
 Frog   643 NQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFA 707

  Fly   562 QFFCSDKELLQAHD------HGSDRKRVNDAVAHFEPFREAFSC 599
            |.:||.:....:|:      |...:.||...:::.:.|.|.|:|
 Frog   708 QVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNC 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:472708	142/694 (20%)
ece2	XP_002935189.1	M13	115..763	CDD:341056	142/694 (20%)