Protein Alignment frma and mmel1

DIOPT Version :10

• Sequence 1: NP_572226.2
• Gene: frma / 31464
• FlyBaseID: FBgn0029769
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_012821551.1
• Gene: mmel1 / 100145721
• XenbaseID: XB-GENE-991673
• Length: 765
• Species: Xenopus tropicalis
• Alignment Length: 768
• Identity: 154/768 - (20%)
• Similarity: 259/768 - (33%)
• Gaps: 216/768 - (28%)

  Fly     5 LRLLELIVGLLVVQVKSH----------------------PQADPCQNFYKVACGNWSASHA--- 44
            |.|:...|..|:|...||                      |..:||.:||:.|||.|...|.
 Frog    53 LFLMTCAVVALLVLYTSHKESICTTTGCVTAAARIIQNMDPTIEPCTDFYQYACGGWLNKHVIPE 117

  Fly    45 TDSYESFMDRLDYNYQEKLADLLDNEREDDEPHFLQQLRNFYTACRKP--LSQDQVLRILEHLIV 107
            |.|..|..|.|....:..|..||:...::|...| ::.:..|.:|...  :.|...|.:||.|..
 Frog   118 TSSRYSIFDILRDEMEIILKGLLEMPDQEDRDAF-KKAKILYKSCMNESLIEQRDSLPLLELLTT 181

  Fly   108 M---------------ENIQNEELSVGLTAAFRLQVLIDLNDSNTYDIWKQLMSHRKHWDPNTTN 157
            :               .|...||....|...|..:||:|:      .:|.......||
 Frog   182 VGEWPVASTDWNGTKESNWSLEEKLSLLNYKFNKRVLVDI------FVWNDDRESSKH------- 233

  Fly   158 REPLTREMFDKLWASLPKIPFPFKEYYWRE--LSELEEKIMSYG-------------SEDDGFDS 207
                      .::...|.:..|.::||:.:  ...:.|..:.:.             :.||....
 Frog   234 ----------IIYIDQPSLGMPSRDYYFNKGNYQRIREAYLQFMITIARMVREDRNLTRDDSLVQ 288

  Fly   208 G------DLVTRIPPFWMMPWPNGNIT--YENLSQMA----------HW------------LDIK 242
            .      ||.|.|...........::|  |..::.:.          :|            :.::
 Frog   289 EEMTRVMDLETDIARATAPSEERNDVTLLYNKMTLLEFQQKFALDDFNWTSFIQGVMSSVNIQLQ 353

  Fly   243 ANEFILTY--IYM-RLKLVAEGVSTES------WHIDRDQCAEQSRQILS--------------H 284
            |.|.::.|  .|: :||.:....|..:      |.:..|:.:..||:...              .
 Frog   354 AEEEVVVYGAPYLHQLKNILSNYSASTLQNYVVWRMVIDRVSSLSRRYKDARASYRKALYGTTLE 418

  Fly   285 PAAW-----LVEKNHPRLKEEPVLQDIFA-ELKQRFGQKLLANRNNFTRSTQHFL----LGKLKR 339
            .|.|     .|..|.........:::.|| |.|:.....:...|..|..:.....    ..|.|.
 Frog   419 EARWRECVSYVNSNMENAVGAMYVKETFAGESKRMISDLINKVREAFIETLDELQWMDETSKDKA 483

  Fly   340 MRLRLSILPRNSSAQSMVR----RIERHYRDVHMNASDYFGNLHIGLNH--SRSHKKYAQ----- 393
            ....|||..:......::.    ::::....::.:...||.|:...||.  .:|.||..:
 Frog   484 REKALSIKEQIGYPDYILEDQNDKLDQETAALNFSEYQYFENILEILNSGAQKSLKKLREPVDQD 548

  Fly   394 LWAIVFGRQLIPSRISKSDLYPTQVRGYGTYASAFYIVKQNMLIVPLSLLEPPFYTHGQPSILTY 458
            .|.|                       ....|.|||...:|.::.|..:|:|||:...||..|.:
 Frog   549 AWII-----------------------GAAVADAFYSPNRNQIVFPAGILQPPFFNKHQPQALNF 590

  Fly   459 SALGFILGHELSHGFDSEGMTFSSHG------VGSSAVDRELDRNPRFQQELGCLRRRFGRKRY- 516
            ..:|.::|||::||||..|..|...|      ...||:        .|:.:..|:..::|...:
 Frog   591 GGIGMVIGHEITHGFDDNGRNFDKDGNMFDWWSNFSAM--------HFKDQSRCMVYQYGNYTWE 647

  Fly   517 --------------EKFADASGLELAYSAYFDTAQTDHKRNRSAEELVTQKQQFFHNFAQFFCSD 567
                          |..||..|:..||.||....:...|..:.....:|.||.||.||||.:|..
 Frog   648 LAGGQNVSGIITLGENIADNGGVRQAYKAYLKWVERHGKEPKLPGLDLTYKQLFFLNFAQVWCGS 712

  Fly   568 ------KELLQAHDHGSDRKRVNDAVAHFEPFREAFSCGPSPRR---RQCRLY 611
                  :..::...|...:.||..::.:||.|.|.|:|....:.   .:||::
 Frog   713 YRPEYARHSIKTDVHSPFKYRVMGSLQNFEAFAEEFNCKKGTKMHPVEKCRVW 765

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frma	NP_572226.2	GluZincin	25..601	CDD:472708	144/711 (20%)
mmel1	XP_012821551.1	M13	95..763	CDD:341056	144/722 (20%)