DRSC/TRiP Functional Genomics Resources

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Protein Alignment SPR and Cysltr2

DIOPT Version :9

Sequence 1:NP_001368972.1 Gene:SPR / 31463 FlyBaseID:FBgn0029768 Length:512 Species:Drosophila melanogaster
Sequence 2:NP_001155884.1 Gene:Cysltr2 / 70086 MGIID:1917336 Length:309 Species:Mus musculus


Alignment Length:372 Identity:78/372 - (20%)
Similarity:133/372 - (35%) Gaps:112/372 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 SYWNLTCDSPLEYAMPLYGYCMPFLLIITIISNSL-------IVLVLSKKSMATPTNFVLMGMAI 132
            ||.|..|... .:....|    |.:.:|.....:|       :.|...|||  |..|..::.:|.
Mouse     9 SYSNRNCTIE-NFKKEFY----PIIYLIIFFWGALGNGFSIYVFLQTCKKS--TSVNVFMLNLAT 66

  Fly   133 CDMLTV-IFPAPGLWYM----YTFGNHYKPLHPVSMC--LAYSIFNEIMPAMCHTISVWLTLALA 190
            .|.|.: ..|....:|.    :.||:        ..|  ::||::..:.      .|::....|:
Mouse    67 SDFLFISTLPFRADYYFRGSNWIFGD--------LACRVMSYSLYVNMY------TSIYFLTVLS 117

  Fly   191 VQRYIYVCHAPMARTWCTMPRVRRCTAYI-------------ALLAFLHQLPRFFDRTYMPLVIE 242
            |.|::...| |......|..|    :|:|             |||....|..:  |.....|.: 
Mouse   118 VVRFLATVH-PFRMFHVTSVR----SAWILCGIIWVFIMASSALLLVNGQEEK--DNIISCLEL- 174

  Fly   243 WNGSPTEVCHLETSMWVHDYIGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQER-- 305
               ||.:.    .|:.:.::|.|.:.      |.:.|:.|..|.:|: :.|||.|.:.::..|  
Mouse   175 ---SPQKF----KSLLIMNHIAVAVG------FLLPFLTLTVCYLLI-IRILLKAEIPESGPRAA 225

  Fly   306 -RKLLFRENRKKECKKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMHIVS-----------SLI 358
             ||.|                 ||:::.::  .|||..:|...:..:|:|:           ...
Mouse   226 HRKAL-----------------TTIVIAMI--TFLLCFLPYHALRTLHLVTWDKDSCGDVLHKAT 271

  Fly   359 IEFLDYGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKEIFL 405
            :..|....||.|.   |.||.:....||      ..:.|..|.::.|
Mouse   272 VITLTMAAANSCF---NPFLYYFAGENF------KARLRAIFSKVHL 309

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SPRNP_001368972.1 7tmA_FMRFamide_R-like 90..400 CDD:410630 72/350 (21%)
TM helix 1 92..116 CDD:410630 5/30 (17%)
TM helix 2 124..146 CDD:410630 5/22 (23%)
TM helix 3 169..191 CDD:410630 2/21 (10%)
TM helix 4 214..230 CDD:410630 6/28 (21%)
TM helix 5 270..293 CDD:410630 5/22 (23%)
TM helix 6 328..353 CDD:410630 5/24 (21%)
TM helix 7 368..393 CDD:410630 7/24 (29%)
Cysltr2NP_001155884.1 7tm_GPCRs 23..300 CDD:391938 71/346 (21%)
TM helix 1 25..49 CDD:341315 4/27 (15%)
TM helix 2 58..79 CDD:341315 5/20 (25%)
TM helix 3 96..118 CDD:341315 4/27 (15%)
TM helix 4 141..157 CDD:341315 2/15 (13%)
TM helix 5 183..206 CDD:341315 6/28 (21%)
TM helix 6 227..252 CDD:341315 9/43 (21%)
TM helix 7 268..293 CDD:341315 7/27 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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