Protein Alignment SPR and sprr-1

DIOPT Version :10

• Sequence 1: NP_001368972.1
• Gene: SPR / 31463
• FlyBaseID: FBgn0029768
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_510555.2
• Gene: sprr-1 / 3564903
• WormBaseID: WBGene00010986
• Length: 527
• Species: Caenorhabditis elegans
• Alignment Length: 401
• Identity: 126/401 - (31%)
• Similarity: 211/401 - (52%)
• Gaps: 55/401 - (13%)

  Fly    76 YWNLTCDS-------PLEYAMPLYGYCMPFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAIC 133
            |:|.||..       |:::|:|:|||.|||::.:|:.:||.||:|||.|.:.||||:||:.||:.
 Worm     9 YYNFTCRPVFIGIMVPVDWAVPMYGYMMPFIVTLTVATNSFIVVVLSHKYLRTPTNYVLLAMAVT 73

  Fly   134 DMLTVIFPAPGLWYMYTFGNHYKPLH---PVSMCLAYSIFNEIMPAMCHTISVWLTLALAVQRYI 195
            ::||.:...|...|.||...:...|.   |...|.........:|::.||:::|||:.||:||||
 Worm    74 ELLTGLSCLPWFTYYYTLSGYKNDLQTGLPSFWCDMIPYMAAFLPSIFHTMAIWLTVYLAIQRYI 138

  Fly   196 YVCHAPMARTWCTMPRVRRCTAYI---ALLAFLHQLPRFFDRTYMPLVIEWNGSPTEVCHLETSM 257
            |:|...:.|.:||:.|.::...:|   |.:.:...|..|.::::.....:.|.: .::|:...:.
 Worm   139 YICVPSLVRKFCTIHRSKQVIFFIISVATIMYTPDLMAFHNKSHDVFDSKRNRT-MKLCYRHRAP 202

  Fly   258 WVHDYIGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQERRKLLF-------RENRK 315
            ::.. :|.|:||...:..:.:.|||:|.::||.....|..|:|.|..|...|.       |..|:
 Worm   203 FMLK-LGDDIYYKVMFTTQTVAVHLIPSVLLVIFTWKLVGAIRVADRRHANLLSKYSTTTRSTRR 266

  Fly   316 K----------------------------ECKKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMH 352
            |                            |.::.......|.||:||:.:||:.|||.|::..:|
 Worm   267 KFSELTNSSENENKITRLFKQRDSVSVGNEPRRAHGLKQNTRMLVVVILLFLITEIPAALIFTIH 331

  Fly   353 IVS-SLIIEFLDYGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKEIFLGRLMA----KK 412
            ::| ||...|:||...||.:::.|..:|.|||..|.||||||:|||:..:::|.|:::.    .|
 Worm   332 VLSVSLKFSFVDYQFLNILLIVRNVLIVVSYPFRFAIYCGMSQQFRDVVRQMFTGKMLTHAIRDK 396

  Fly   413 DSSTKYSIVNG 423
            |:||...:|.|
 Worm   397 DNSTTMQLVQG 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SPR	NP_001368972.1	7tmA_FMRFamide_R-like	90..400	CDD:410630	112/351 (32%)
		TM helix 1	91..117	CDD:410630	14/25 (56%)
		TM helix 2	123..148	CDD:410630	9/24 (38%)
		TM helix 3	168..198	CDD:410630	13/29 (45%)
		TM helix 4	210..230	CDD:410630	4/22 (18%)
		TM helix 5	269..294	CDD:410630	7/24 (29%)
		TM helix 6	322..355	CDD:410630	12/32 (38%)
		TM helix 7	368..393	CDD:410630	12/24 (50%)
sprr-1	NP_510555.2	7tmA_FMRFamide_R-like	30..380	CDD:410630	112/351 (32%)
		TM helix 1	31..57	CDD:410630	14/25 (56%)
		TM helix 2	63..88	CDD:410630	9/24 (38%)
		TM helix 3	111..141	CDD:410630	13/29 (45%)
		TM helix 4	153..175	CDD:410630	3/21 (14%)
		TM helix 5	213..238	CDD:410630	7/24 (29%)
		TM helix 6	265..331	CDD:410630	14/65 (22%)
		TM helix 7	348..373	CDD:410630	12/24 (50%)