DRSC/TRiP Functional Genomics Resources

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Protein Alignment SPR and sprr-2

DIOPT Version :9

Sequence 1:NP_001368972.1 Gene:SPR / 31463 FlyBaseID:FBgn0029768 Length:512 Species:Drosophila melanogaster
Sequence 2:NP_510455.2 Gene:sprr-2 / 181575 WormBaseID:WBGene00009629 Length:451 Species:Caenorhabditis elegans


Alignment Length:436 Identity:135/436 - (30%)
Similarity:211/436 - (48%) Gaps:79/436 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 GNESLDYPNYQ--QMVGGPCRMEDNNISYW---NLTCDSPLEYAMPL----------YGYCMPFL 99
            ||...: ||..  |.:...|..:|  .||:   :.||... :|.:||          ||...|.|
 Worm     8 GNAHAE-PNSSAVQQLAEACVEQD--ASYFDGCSRTCVKD-KYLLPLTQFDNLEIVVYGQIFPIL 68

  Fly   100 LIITIISNSLIVLVLSKKSMATPTNFVLMGMAICDMLTVIFPAPGLWYMYTFGNHYKPLHPVSM- 163
            ::..:.:|:.:.||||||.|.||||.||..|||.::|..:.|.|...:.::.|| .|..|.:.: 
 Worm    69 VLFAVFANAAVALVLSKKHMITPTNVVLKYMAIAELLVGLVPLPWTLFFFSMGN-IKETHRLELW 132

  Fly   164 -CLAYSIFNEIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQ 227
             |.......:..|.:.|.|::|||:.||.|||:.:.|...:|:.|.:..||..|..|.:.:||..
 Worm   133 WCYLQKYSMDAFPPVFHMIAMWLTVLLAAQRYVSISHPLHSRSACNVKNVRLATMIITVTSFLCG 197

  Fly   228 LPRFFDRTYMPLVIEWNGSPTEVCHLETSMWVHDY-------------------IGVDLYYTSYY 273
            ||:.||..|            |..|    .|::.:                   :|..:|:..|:
 Worm   198 LPKSFDYEY------------ETVH----GWIYSHGNWTYASSCVMMPTAILTNMGQTVYFNIYF 246

  Fly   274 LFRVLFVHLLPCIILVTLNILLFAAMRQAQERRKLLFRENRKKECKKLRETNCTTLMLIVVVSVF 338
            ..|.|...:||..:||.||.||...:|:||.|:..|.||.|.:|..:.|::|.|:|||:.:||:|
 Worm   247 WTRALGFIILPSFLLVLLNGLLIKGIRRAQRRKLRLLREKRSEEAARQRDSNSTSLMLVAIVSIF 311

  Fly   339 LLAEIPIAVVTAMHIVS---SLIIEFLDYGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETF 400
            |:..:|.|:...:..|.   ::.|..|:.....:.::.:|..::.:|||||||||.||..||:||
 Worm   312 LIVNLPQAIFMGLLCVCETFTIKIPILEGTFPAVFLIASNMIVIATYPINFGIYCFMSSSFRQTF 376

  Fly   401 KEIF---LGRLMAKK--------DSSTKYS-----IVNGARTCTNT 430
            |.:|   ..:|..::        .||.:.|     :||   .|||:
 Worm   377 KLLFCPGASQLQCERRIEAASAVHSSRRRSDICSHLVN---VCTNS 419

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SPRNP_001368972.1 7tmA_FMRFamide_R-like 90..400 CDD:410630 110/343 (32%)
TM helix 1 92..116 CDD:410630 8/23 (35%)
TM helix 2 124..146 CDD:410630 9/21 (43%)
TM helix 3 169..191 CDD:410630 7/21 (33%)
TM helix 4 214..230 CDD:410630 5/15 (33%)
TM helix 5 270..293 CDD:410630 8/22 (36%)
TM helix 6 328..353 CDD:410630 9/24 (38%)
TM helix 7 368..393 CDD:410630 10/24 (42%)
sprr-2NP_510455.2 7tmA_FMRFamide_R-like 59..376 CDD:410630 108/333 (32%)
TM helix 1 61..85 CDD:410630 8/23 (35%)
TM helix 2 93..115 CDD:410630 9/21 (43%)
TM helix 3 139..161 CDD:410630 7/21 (33%)
TM helix 4 184..200 CDD:410630 5/15 (33%)
TM helix 5 243..266 CDD:410630 8/22 (36%)
TM helix 6 301..323 CDD:410630 9/21 (43%)
TM helix 7 344..369 CDD:410630 10/24 (42%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 187 1.000 Domainoid score I1980
eggNOG 1 0.900 - - E1_28P11
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG29192
OrthoDB 1 1.010 - - D421120at33208
OrthoFinder 1 1.000 - - FOG0004530
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_114040
Panther 1 1.100 - - O PTHR47023
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
87.880

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