DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment spoon and krimp

DIOPT Version :9

Sequence 1:NP_726992.2 Gene:spoon / 31459 FlyBaseID:FBgn0263987 Length:607 Species:Drosophila melanogaster
Sequence 2:NP_611103.2 Gene:krimp / 36804 FlyBaseID:FBgn0034098 Length:746 Species:Drosophila melanogaster


Alignment Length:476 Identity:83/476 - (17%)
Similarity:157/476 - (32%) Gaps:134/476 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   117 EKDSPTTMLYGKSAPIKIQSNGRTSNGKHQQQIDSEILKSKIQ-----------DAEHKTLCSID 170
            ||.|...:||....|:........|      ::::.::|..:|           |.|:... |||
  Fly    40 EKLSHADLLYRSLIPLHDHLVASLS------EVNAHVMKLNVQLHINRQSVRLGDYEYYEK-SID 97

  Fly   171 EDFENLSSPRD----------------------LPDSVNTRVSFYNRKATQKTVEPVVIKATRTP 213
            ..:.::.|...                      ||.|.:..|             |||    ...
  Fly    98 NPYSSIRSGLQAIEKPGCAEAICQSSKPAFVECLPSSTSEEV-------------PVV----AVQ 145

  Fly   214 KISPENSFLDTNYTNKECEQNNNCEPK--------EEPSKKEADQEELEQDQEQ------TVLKE 264
            :.|..|.....:..|:...:..:..|:        ||........|:||...|:      .|::.
  Fly   146 EASSTNQLDAISVVNENLSEERDATPQPLAVSKNMEETMPSNPFHEQLEGSLEEIPVGSKIVVET 210

  Fly   265 EVVDSNGNQKRNVDAASPSLSICSVQSGDSGKGSSLPRSEATRVKTTYEFLFPISLIGHLYGRKR 329
            |..::....:.:..|.|.:.|:.:.:.|....|:.:                             
  Fly   211 EKANNPVRSEASAPATSDNQSLLAAKQGTQTIGTGI----------------------------- 246

  Fly   330 AFINQIKAKTLASVSVGKNPYSGKVRICTIEGTESEIDAALAMIRQRLPAKRYPNFTMQRIHFAL 394
              .|:|...|:      ..|.:.::.      ..:|:.||......:||......|.:.      
  Fly   247 --CNKISKSTI------NMPNNWQLE------NPTEVTAASIEKVNKLPKSPRNRFLLP------ 291

  Fly   395 PQTIVPLSTESLYNLQLKLIEGINNDVVVSAVLSGSHI-----FIQHPLHPSHPSLPLLQKQLYD 454
            |:.....:...:||..||.:.....:.:|:|||:...:     ::......|.....:||:||  
  Fly   292 PKGGTETTRRDIYNQILKDMAAFPENTIVTAVLASVDVTDNCAYVAKWDESSDRIKKVLQRQL-- 354

  Fly   455 SYSTMEAPLLPSL-ELSAVCVIPINDVWYRVQIVDTDPEDEERCVIKFLDFGGYMNV-GFNTLRQ 517
              ...|...||.. ::.|| :..||::..|:.|..:.........:  :|||.:::. |..|:.:
  Fly   355 --PLQELDQLPDYGDIFAV-LDSINNIITRITINSSSAGGGYDAYL--IDFGEHIHFDGNETIFK 414

  Fly   518 IRTDFMNVPFQSTECILSNIE 538
            :..|...:|.|:..|.|.|.:
  Fly   415 LPDDIKRLPAQAIRCDLINCD 435

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
spoonNP_726992.2 KH-I 311..373 CDD:238053 7/61 (11%)
TUDOR 413..536 CDD:278965 28/129 (22%)
TUDOR 465..522 CDD:295375 12/58 (21%)
krimpNP_611103.2 TUDOR 568..679 CDD:278965
TUDOR 618..662 CDD:119391
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR22948
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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