Protein Alignment spoon and Akap1

DIOPT Version :10

• Sequence 1: NP_726992.2
• Gene: spoon / 31459
• FlyBaseID: FBgn0263987
• Length: 607
• Species: Drosophila melanogaster
• Sequence 2: NP_446117.2
• Gene: Akap1 / 114124
• RGDID: 620826
• Length: 854
• Species: Rattus norvegicus
• Alignment Length: 747
• Identity: 183/747 - (24%)
• Similarity: 294/747 - (39%)
• Gaps: 208/747 - (27%)

  Fly    26 GRPLL--YLSLPGVAF-------ILGVFWFRRRYKNCLDKPDDEDSSAINDSSIEPTVQARKANG 81
            ||||.  .||.|..|.       .||    |...:..|.:......:|......|.|..|.....
  Rat   142 GRPLFPKDLSFPYEAVEGCKQESALG----RTPGRGWLSQCAASGENARETGGAEGTGDAVLGES 202

  Fly    82 VLQNGKLPQQSASK-SMNINGTLVNGSGSGSGSSS-----DEKDSPTTMLYGK-----SAPIK-- 133
            ||:.|.|||:..|: ..:....|..|.|.|....|     ||.......:.||     ..|:.
  Rat   203 VLEEGLLPQECVSEVEKSEFPILAPGGGGGEKVRSGPPQVDELLKKEEYIVGKLPSSFVGPVHSE 267

  Fly   134 -IQSNG---------------------RTSNGKHQ-QQIDSEILKSKIQDAEH--------KTLC 167
             ::..|                     :|...|.| :|...:|:...|.:|..        ||:.
  Rat   268 LVKDEGALVPQVKGSQDRSLARELDKDKTLPEKDQIEQTAFQIISQVILEATEEIRATTVGKTVA 332

  Fly   168 SI-----------DED----FENLSSPRDLPDSVNTRVSFYNRKATQKTVEPV------------ 205
            .:           :|.    .:..|..:::||..:||        |..|..|.
  Rat   333 QVHPTPGTQPQGQEESCVPASQETSLGQEIPDPASTR--------TGATASPSAGAPPPKTYVSC 389

  Fly   206 --------------------VIKATRTPKISPENSFLD------TNYTNKECEQNNN-------- 236
                                :..|...|.::|:...||      .:.|...|..||:
  Rat   390 LSSPLSGPTKDQKPKNSAHHISLAPCPPPVTPQRQSLDGASNPRGDDTFVTCTSNNSQSVLSVTS 454

  Fly   237 ---CEPKEEPSKKEADQEEL---EQDQEQT-------------VLKEEVVD-------------- 268
               |......|:.|....|.   ..|:..|             |||||:.|
  Rat   455 LGLCSDPVSTSRLEDSCTETISSSGDKAVTPPLPDSTEPFSNGVLKEELSDLGTEDGWTMDTEAD 519

  Fly   269 ----SNGNQKRNVDAA-------SPSLSICSVQSGDSGKGSSLPRSEATRVKTTYEFLFPISLIG 322
                |:||...:||:.       ||.    :||:|.:.|...|         ..:|...|..|:|
  Rat   520 HSGGSDGNSMDSVDSCCGLTKPDSPQ----TVQAGSNPKKVDL---------IIWEIEVPKHLVG 571

  Fly   323 HLYGRKRAFINQIKAKTLASVSVGKNPYSGKVRICTIEGTESEIDAALAMIRQRLPAKRYPNFTM 387
            .|.|::..:::.:|..:.|.:.:...||:..::||.|||::..:|.||.:|     .|::....:
  Rat   572 RLIGKQGRYVSFLKQTSGAKIYISTLPYTQNIQICHIEGSQHHVDKALNLI-----GKKFKELNL 631

  Fly   388 QRIH------FALPQTIVPLSTESLYNLQLKLIEGINNDVVVSAVLSGSHIFIQHPLHPSHPSLP 446
            ..|:      .|||.  :|:::      .|.|.:||..:|:|...::..|:|:|...||:..:|.
  Rat   632 TNIYAPPLPSLALPS--LPMTS------WLMLPDGITVEVIVVNQVNAGHLFVQQHTHPTFHALR 688

  Fly   447 LLQKQLYDSYSTMEAPLLPS-LELSAVCVIPIND-VWYRVQIVDTDPEDEERCVIKFLDFGGYMN 509
            .|.:|:|..||....|.||: :|::.:|..|..| .|:|.|:|.:..|..| ..|:::|:|||..
  Rat   689 SLDQQMYLCYSQPGIPTLPTPVEITVICAAPGADGAWWRAQVVASYEETNE-VEIRYVDYGGYKR 752

  Fly   510 VGFNTLRQIRTDFMNVPFQSTECILSNIEPIGGT--WSIEAAEILNKLTKGIVLQAQVAGYNSHN 572
            |..:.|||||:||:.:|||..|.:|.::.|:...  :|.||...::::|....|.|||..|::..
  Rat   753 VKVDVLRQIRSDFVTLPFQGAEVLLDSVVPLSDDDHFSPEADAAMSEMTGNTALLAQVTSYSATG 817

  Fly   573 LPEIFLFASLGPNNVIFINKELVGRKLAKWVE 604
            ||.|.|::.:| :.|:.||:.||.|.||:||:
  Rat   818 LPLIQLWSVVG-DEVVLINRSLVERGLAQWVD 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spoon	NP_726992.2	KH-I	311..378	CDD:469614	19/66 (29%)
		Tudor_AKAP1	463..539	CDD:410478	30/77 (39%)
Akap1	NP_446117.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	62..115
		PKA-RII subunit binding domain	303..316		2/12 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..437		14/111 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	473..495		3/21 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	509..551		9/45 (20%)