Protein Alignment Usp16-45 and UBP1

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_010161.1
• Gene: UBP1 / 851435
• SGDID: S000002280
• Length: 809
• Species: Saccharomyces cerevisiae
• Alignment Length: 979
• Identity: 162/979 - (16%)
• Similarity: 268/979 - (27%)
• Gaps: 444/979 - (45%)

  Fly   279 TTNGNTGNKRLLTLETPR-----IENERLPR---VRGLTNLGNTCFFNAVMQCLAQTPFLLSVLK 335
            |||....|.  |:...||     ::.|.|.|   :.||.|.|||||.|:|:|.||.:
Yeast    68 TTNFRNNNS--LSRWLPRSKFTHLDEEILKRGGFIAGLVNDGNTCFMNSVLQSLASS-------- 122

  Fly   336 ELSEPGEEFILPGGTFTIKDKGDIELPMIKGTLSSWGGLTAALANALEELQAGGSVFTPRKLFDR 400
                                                                             
Yeast   123 ----------------------------------------------------------------- 122

  Fly   401 LCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKD-------QDVNSVSEEMR 458
                                |:|:|.:.|..::.|:. |.||...::       ||..:..:..|
Yeast   123 --------------------RELMEFLDNNVIRTYEE-IEQNEHNEEGNGQESAQDEATHKKNTR 166

  Fly   459 QKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEKPQPPQRRKPS 523
            :..|:||                                                       |..
Yeast   167 KGGKVYG-------------------------------------------------------KHK 176

  Fly   524 PELSLTSSSSSVTPSTGQPTINTKFTDGSVNFTASSPSFFLHAHEAASLGPSKSQVKKEKERQRK 588
            .:|:..|||......:.:|.|                :|.:...:..|...:|....|...:...
Yeast   177 KKLNRKSSSKEDEEKSQEPDI----------------TFSVALRDLLSALNAKYYRDKPYFKTNS 225

  Fly   589 AKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQANDGLEQTNGQTEDSTTSS 653
            ..:|..|..:.:: |.|.|..:..|..:::      ||.|.:.....|         ||...|:.
Yeast   226 LLKAMSKSPRKNI-LLGYDQEDAQEFFQNI------LAELESNVKSLN---------TEKLDTTP 274

  Fly   654 VTTSEHSDADVEDNLVEDTAAPSTNNVPSSTASLTAPSKTYMDSNGNAQPPGEKRDDTPEHMDKD 718
            |..||..|    |.||             ...:|......|:.:               |.:|.:
Yeast   275 VAKSELPD----DALV-------------GQLNLGEVGTVYIPT---------------EQIDPN 307

  Fly   719 SLEEDENDSGIA----TSPAPTATNSSTSTSATGNNNSVAGSGLSGSSGALEDPLAPASLVTAGL 779
            |:..|::.....    .:|....|.........|.|..:..|..||.|  |..|
Yeast   308 SILHDKSIQNFTPFKLMTPLDGITAERIGCLQCGENGGIRYSVFSGLS--LNLP----------- 359

  Fly   780 SEKGASVIRQVSVGAEQGASNGTEDADGEAKAIEQPEKTPSQAQAMAQAQARTKRVRTQSYSDWS 844
            :|...|.::                                               .:|..||||
Yeast   360 NENIGSTLK-----------------------------------------------LSQLLSDWS 377

  Fly   845 -TTIAPRYQCEDGECSVQSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPK-------------- 894
             ..|....:|  ..|::.:..::      :.||.|    ...::..||.|:
Yeast   378 KPEIIEGVEC--NRCALTAAHSH------LFGQLK----EFEKKPEGSIPEKLINAVKDRVHQIE 430

  Fly   895 ---AKSV----------------NTNATKQLLVSSPPAVLILHLKRFQLGPRC-IFRKLTRPVSY 939
               ||.|                ..:.:||:|:|.||.:|.:|:.|....||. :.||....|.:
Yeast   431 EVLAKPVIDDEDYKKLHTANMVRKCSKSKQILISRPPPLLSIHINRSVFDPRTYMIRKNNSKVLF 495

  Fly   940 PNLLDIAAFCGSKVKNLPNID-----RKQKKLLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGD 999
            .:.|::|.:|..  .|..|:|     .|::|.........|:.||.|      |.|:
Yeast   496 KSRLNLAPWCCD--INEINLDARLPMSKKEKAAQQDSSEDENIGGEY------YTKL-------- 544

  Fly  1000 KRWKFLPHGSKAELDQDDDQLKKLEELLAKEKAREQHLKVL---------------DDSDDFSNS 1049
                   |....:..:|.::.|:.::......:...|.|.:               ||.|::...
Yeast   545 -------HERFEQEFEDSEEEKEYDDAEGNYASHYNHTKDISNYDPLNGEVDGVTSDDEDEYIEE 602

  Fly  1050 S------------SNSSTSDESQTPATPLEEQQTQQAQQPQ--QPQQLEEAAN----VRAPP--- 1093
            :            .:|...:|:......|:|.......:|:  ...|||.:::    :.|||
Yeast   603 TDALGNTIKKRIIEHSDVENENVKDNEELQEIDNVSLDEPKINVEDQLETSSDEEDVIPAPPINY 667

  Fly  1094 --------------------------------------GKWYYVSDSRVQEVSEDTALKAQ-AYL 1119
                                                  |.|:.:||..|..|.|...|... .::
Yeast   668 ARSFSTVPATPLTYSLRSVIVHYGTHNYGHYIAFRKYRGCWWRISDETVYVVDEAEVLSTPGVFM 732

  Fly  1120 LFYE 1123
            ||||
Yeast   733 LFYE 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464
		UBP12	<307..990	CDD:227847	120/733 (16%)
		Peptidase_C19	307..>512	CDD:470612	27/211 (13%)
		Peptidase_C19K	<849..1123	CDD:239132	68/387 (18%)
UBP1	NP_010161.1	Peptidase_C19	101..>293	CDD:470612	59/389 (15%)
		Peptidase_C19F	102..736	CDD:239127	150/941 (16%)
		Peptidase_C19	<427..>510	CDD:470612	20/84 (24%)