Protein Alignment Usp16-45 and Ggnbp1

DIOPT Version :9

• Sequence 1: NP_001284890.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_081820.2
• Gene: Ggnbp1 / 70772
• MGIID: 3055306
• Length: 370
• Species: Mus musculus
• Alignment Length: 526
• Identity: 97/526 - (18%)
• Similarity: 155/526 - (29%)
• Gaps: 236/526 - (44%)

  Fly   164 RKNLLECVELVK--------KLAQKPPTSTVTPSTPTISYIEEKLKAALEHLTPIVPMTG--GSF 218
            |..:|.|..:::        |...|.....:|.|.|:.|:.::          .:.||.|  |..
Mouse     9 RSRILGCSSMLRFLRNLVGSKGGSKSTNKPLTRSQPSSSWEQD----------VVSPMMGHQGGR 63

  Fly   219 DDSSSRGSLAAAGGGGGVGSSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGN 283
            .....|..:.:|....|     .|:     |||...|...::          .|.|.:...| |:
Mouse    64 GRKEPRAKVHSAASSNG-----KRE-----PPPRVLSAAPSN----------PRHDAFELGT-GD 107

  Fly   284 TGNKRLLTLETPRIENERLPRVRGLTNLGNTCFFNAVMQCLAQTPF--LLSVLKELSEPGEEFIL 346
            :|::.|.:.:.|::      |.:|:.              :...|.  ...||::|.|
Mouse   108 SGSQTLTSKDVPKL------RAQGVE--------------VTSVPLRGTWEVLEQLPE------- 145

  Fly   347 PGGTFTIKDKGDIELPMIKGTLSSWGGLTAA-----LANALEELQAGGSVFTPRKLFDRLCVKCP 406
                    .||:.|.|:        |.::.|     ...|||..|.                 |.
Mouse   146 --------KKGEEEEPV--------GEVSGASDREHFGQALETEQG-----------------CL 177

  Fly   407 QFTGGDQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDR 471
            |:..|.                         :.|....:       :.||..:.|.|   :.||
Mouse   178 QWVPGP-------------------------LALTPGAF-------IKEEEDEHCPI---EFGD- 206

  Fly   472 ILRPEQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPV---AVEKPQPPQRRKPSPELSL----- 528
             |:|              ..|...|:...|.|.:...:   |:.|.|.|    .:|:|:|
Mouse   207 -LKP--------------SSCKVGSTPWNYLLGLYKQLQKSAMAKAQRP----AAPQLALKDGLP 252

  Fly   529 ---------------------TSSSSSVTP-------STGQPTINTKF--TDGSVNFTASSPSFF 563
                                 .:||....|       ||.|..:..||  ||
Mouse   253 HEEKGEREEAVDESCPKWCAPRASSDESCPKWCAPRASTYQSPLQKKFRSTD------------- 304

  Fly   564 LHAHEAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASL 628
                   ::|..:|::||....||:|:          |...||..|.     |.:.|.|.:|...
Mouse   305 -------TVGFVESELKKILSVQREAR----------LWKVGNPEGR-----ELLTQPDITLEEA 347

  Fly   629 GAGDGQ 634
            |..|||
Mouse   348 GMVDGQ 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_001284890.1	zf-UBP	108..159	CDD:280334
		Peptidase_C19	307..>512	CDD:271592	33/214 (15%)
		Peptidase_C19K	<849..1123	CDD:239132
Ggnbp1	NP_081820.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..114		23/118 (19%)
		Required for induction of mitochondrial fragmentation	225..370		36/168 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..263		4/26 (15%)
		Ubiquitin_3	281..368	CDD:291502	27/108 (25%)
		Interaction with GGN	298..370		23/91 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5560
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900