Protein Alignment Usp16-45 and Usp51

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_001131019.1
• Gene: Usp51 / 635253
• MGIID: 3588217
• Length: 661
• Species: Mus musculus
• Alignment Length: 1061
• Identity: 173/1061 - (16%)
• Similarity: 251/1061 - (23%)
• Gaps: 567/1061 - (53%)

  Fly     5 RQADSRDHDCSTDS-GNEDLHHRKGLGSPGQSDGATPTTASCQHIKKAVDAARLRRLLKSTGLLY 68
            |::.|.||..|.|| |:|:     .|...|.:.|.|    .|.|::....|...:|.|:   ::|
Mouse   119 RKSYSSDHGSSRDSDGSEN-----SLLEVGSNKGPT----GCCHVESFKVAKNWQRNLR---MIY 171

  Fly    69 E-------------------CSQCQKLGKTAGSAAGAGASEGAVGPGGNPVTFEFDNTLWLCLKC 114
            :                   |..|.                            ...|.|..||.|
Mouse   172 QRFIWSGTPETRKRKAKSCICQICS----------------------------THKNRLHSCLSC 208

  Fly   115 GSQLCGRARHKHALEHYQTPHSDSHALAMNTRSFDIWCYEC-DMKICSNLRKNLLECVELVKKLA 178
            ....|...:|.|.  |.:|   ..|.||::.....|:|:.| |.....::.|...|..|.:..|.
Mouse   209 VFFGCFTDKHIHI--HAET---TQHNLAVDLCHGVIYCFMCRDYVYDKDIEKIAKETKEKILGLL 268

  Fly   179 QKPPTSTVTPSTPTISYIEEKLKAALEHLTPIVPMTGGSFDDSSSRGSLAAAGGGGGVGSSRNRQ 243
                      |:||                                            |.:..:|
Mouse   269 ----------SSPT--------------------------------------------GDASYQQ 279

  Fly   244 VAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGNTGNKRLLTLETPRIENERLPRV--R 306
            :                        ||..:::...|.........|:..:..|.:......|  |
Mouse   280 L------------------------MASEVEENQLTCESKDQETSLVKPKKKRRKKTMYYTVGFR 320

  Fly   307 GLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMIKGTLSSW 371
            ||.|||||||.|.::|.|...|.|           :||.|..     |.|..:..|.:
Mouse   321 GLINLGNTCFMNCIVQVLTHIPLL-----------KEFFLSN-----KHKCMMTSPSL------- 362

  Fly   372 GGLTAALANALEELQAGG-SVFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRY 435
             .|...::...:.:.:|. |...|.||...:.:......|..|.||.|.|..:|:.     |.|:
Mouse   363 -CLVCEMSLLFQAMYSGNQSPHIPYKLLHLIWIHAEHLAGYRQQDAQEFLIAILDV-----LHRH 421

  Fly   436 QRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHE 500
            .|         |..::.........|.|            :.:|.|.|.|.||||.||.||:..:
Mouse   422 SR---------DDGIDQEGNSNCCNCII------------DHIFTGSLQSDLTCQVCHGVSTTID 465

  Fly   501 YFLDMSLPVAVEKPQPPQRRKPSPELSLTSSSSSVTPSTGQPTINTKFTDGSVNFTASSPSFFLH 565
            ...|:||
Mouse   466 PCWDISL---------------------------------------------------------- 472

  Fly   566 AHEAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGA 630
                                                                             
Mouse   473 ----------------------------------------------------------------- 472

  Fly   631 GDGQANDGLEQTNGQTEDSTTSSVTTSEHSDADVEDNLVEDTAAPSTNNVPSSTASLTAPSKTYM 695
                                                    |...|.|
Mouse   473 ----------------------------------------DLPGPYT------------------ 479

  Fly   696 DSNGNAQPPGEKRDDTPEHMDKDSLEEDENDSGIATSPAPTATNSSTSTSATGNNNSVAGSGLSG 760
                    ||.
Mouse   480 --------PGR------------------------------------------------------ 482

  Fly   761 SSGALEDPLAPASLVTAGLSEKGASVIRQVSVGAEQGASNGTEDADGEAKAIEQPEKTPSQAQAM 825
                                                 ||:.|...||:
Mouse   483 -------------------------------------ASSSTSSRDGQ----------------- 493

  Fly   826 AQAQARTKRVRTQSYSDWSTTIAPRYQCEDGECSVQSCLNNFTAVELMTGQNKVGCDSCTQRING 890
                                  .||.      .|:..||..||..|.:....|:.|..|..
Mouse   494 ----------------------KPRV------ISLTDCLKWFTRPEDLGSSAKIKCSQCQS---- 526

  Fly   891 SDPKAKSVNTNATKQLLVSSPPAVLILHLKRFQ-LGPRCIFRKLTRPVSYPNLLDIAAFCGSK-- 952
                    ...:||||.:...|.|...|||||: ||.:  .||:...:|:|..||:..|..|.
Mouse   527 --------YQESTKQLTMKKLPIVACFHLKRFEHLGKQ--RRKINSFISFPLELDMTPFLASTKE 581

  Fly   953 --VKNLPNIDRKQKKLLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQ 1015
              :|..|..:....:..|:|:.|:.|.|.:..||||::|                    :.|.||
Mouse   582 SIMKGQPLTECVPSENKYSLFAVINHHGTLESGHYTSFV--------------------RQEKDQ 626

  Fly  1016 ----DDDQLKK--LEELLAKE 1030
                ||..:.|  :||||..|
Mouse   627 WFSCDDAVVTKATMEELLNSE 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464	16/51 (31%)
		UBP12	<307..990	CDD:227847	107/688 (16%)
		Peptidase_C19	307..>512	CDD:470612	54/205 (26%)
		Peptidase_C19K	<849..1123	CDD:239132	55/193 (28%)
Usp51	NP_001131019.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..144		10/29 (34%)
		zf-UBP	192..252	CDD:460464	19/92 (21%)
		Peptidase_C19D	320..654	CDD:239125	120/737 (16%)