DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp16-45 and Ggnbp1

DIOPT Version :9

Sequence 1:	NP_001284890.1	Gene:	Usp16-45 / 31458	FlyBaseID:	FBgn0029763	Length:	1126	Species:	Drosophila melanogaster
Sequence 2:	XP_006256187.1	Gene:	Ggnbp1 / 494520	RGDID:	1359729	Length:	377	Species:	Rattus norvegicus

Alignment Length:	462	Identity:	102/462 - (22%)
Similarity:	149/462 - (32%)	Gaps:	165/462 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   221 SSSRGSLAAAGGGGGVGSSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGNTG 285
            ||....|.:..|..|...|.||    |:...:|||  |....:.| |.|..:         |..|
  Rat    16 SSMLRFLRSLVGSKGSSKSSNR----PLNRSQPSS--SPEQDVVS-PTMGHQ---------GGCG 64

  Fly   286 NK----RLLTLET--------PRI-----ENERLPRVRGLTNLGNTCFFNAVMQCLAQTPFLLSV 333
            .|    |:|:..:        ||:     .|:||....|| ..|:|.         :||.....|
  Rat    65 RKETRPRVLSATSSNGKREPRPRVLSAAPSNQRLRDASGL-GTGDTG---------SQTLTSKDV 119

  Fly   334 LKELSEPGEEFILP-GGTFTI-----KDKGDIELPM--IKGTLSSWGGLTAALANALEELQAGGS 390
            ||..::..|...:| .||:.:     :.||:...|.  :.|...|: |:.|....|||..|.
  Rat   120 LKLRAQGVEVTSVPTRGTWEVLEHLPEKKGEEGEPAGEVSGASDSF-GIRAHFGQALEAEQG--- 180

  Fly   391 VFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSE 455
                          |.|:..|.                         ::|....:       :.|
  Rat   181 --------------CLQWVSGP-------------------------MVLPPEAF-------IKE 199

  Fly   456 EMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPV---AVEKPQPP 517
            |..:.|.|   ..||                |....|...|:...|.|.:...:   |:.|.|.|
  Rat   200 EEDEHCLI---DFGD----------------LRLSSCKVGSTPWNYLLGLYKQLQKSAMTKAQRP 245

  Fly   518 QRRKPSPELSLTSSS--------------SSV---TPSTGQPTINTKFTDGSVNFTASSP---SF 562
            .  ..:|:.:|..||              ||:   .|.......|.|:. ...|.|..||   :|
  Rat   246 D--ADAPQFALKDSSPTEERGEREEAVDESSLKWCAPRASSDDSNLKWC-APRNSTYQSPLQKTF 307

  Fly   563 FLHAHEAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLAS 627
                ....::|..:|::||....||:|:          |...||..|.     |.:.|.|.:|..
  Rat   308 ----RSTDTVGFVESELKKILAVQREAR----------LWKVGNPEGR-----ELLTQPDITLEE 353

  Fly   628 LGAGDGQ 634
            .|..|||
  Rat   354 AGMVDGQ 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_001284890.1	zf-UBP	108..159	CDD:280334
		Peptidase_C19	307..>512	CDD:271592	40/215 (19%)
		Peptidase_C19K	<849..1123	CDD:239132
Ggnbp1	XP_006256187.1	Ubiquitin_3	289..375	CDD:291502	25/92 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5560
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900