Protein Alignment Usp16-45 and usp16

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_001072158.1
• Gene: usp16 / 447956
• XenbaseID: XB-GENE-1007164
• Length: 864
• Species: Xenopus tropicalis
• Alignment Length: 1145
• Identity: 309/1145 - (26%)
• Similarity: 462/1145 - (40%)
• Gaps: 330/1145 - (28%)

  Fly    26 RKGLGSPGQ-SDGATPTTASCQHIKKAVDAARLRRLLKSTGLLYECSQCQKLGKTAGSAAGAGAS 89
            ::|...|.| |..|.|.   |:|::||:|...:::.|.:..... |.:||...|...::......
 Frog     4 KRGKNLPAQDSLDAEPV---CKHLRKALDEGSVKKALVNVEWTV-CQECQADNKEKNNSDDELVE 64

  Fly    90 EGAVGPGGNPVTFEFDNTLWLCLKCGSQLCGR-ARHKHALEHYQTPHSDSHALAMNTRSFDIWCY 153
                           |.::|||||||.:.||| :..:|||.||.||.|:.|.|.::...:..|||
 Frog    65 ---------------DPSVWLCLKCGHRGCGRNSASQHALNHYNTPRSEPHCLVLSMDMWSAWCY 114

  Fly   154 ECDMKICSNLRKNLLECVELVKKLAQKPPTSTVTPSTPTISYIEEKLKAALEHLTPIVPMTGGSF 218
            .||.::..|....|.:.|:.:::.|:....||.:.:      ::|::||.:
 Frog   115 LCDNEVPYNRSSRLGQLVDYLQRKAKAKSKSTDSAA------LDEEVKAEI-------------- 159

  Fly   219 DDSSSRGSLAAAGGGGGVGSSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGN 283
                                ....:|.|.....:|.             |.|| .|:.|:|.|.:
 Frog   160 --------------------VAENEVKIEDQEEKPK-------------GQAK-WDKASSTQNNS 190

  Fly   284 TGNKRLLTLETPRIENERLPRVRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPG 348
            |.                 |.|:||:|||||||||||||.|:|||.:..:|.|.....:...:|.
 Frog   191 TE-----------------PTVKGLSNLGNTCFFNAVMQNLSQTPAVRELLNEAKTLKKPVTVPL 238

  Fly   349 GTFTIKDKGDIELPMIKG--TLSSWGGLTAALANALEELQAGGSVFTPRKLFDRLCVKCPQFTGG 411
            ...:.....::.|....|  ||:.|..||     .::|.:.|  |.||:::|.::|.|..:|.|.
 Frog   239 PDSSSPTNVEVHLEQQPGPLTLAMWQFLT-----EMQETKKG--VVTPKEVFSQVCKKAIRFKGY 296

  Fly   412 DQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRP- 475
            .|.|:.||||.||:.:|.|:::|....:.::|      .|::.||  :..||..:....|.: |
 Frog   297 QQQDSQELLRYLLDGMRGEEIQRVSLAMSKSL------QNTLDEE--EIKKIVKDSEKRRTI-PN 352

  Fly   476 --EQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPV---AVEKPQPPQRRKPSPELSLTSSSSSV 535
              :.:|.|.|.||:.|::||.||..||.|||:||||   .:.|....:...|.||......:.
 Frog   353 FVDHLFGGELTSTIMCEECHTVSLVHEPFLDLSLPVLDDVIVKKNSQKSSAPVPERKEEEEND-- 415

  Fly   536 TPSTGQPTINTKFTDGSVNFTASSPSFFLHAHEAASLGPSKSQVKKEKERQRKAKRAAKKR---Q 597
                          ||           ::...:.||.|.|       |..|:|||:||||:   |
 Frog   416 --------------DG-----------YIKERDEASPGAS-------KHLQKKAKKAAKKQAKNQ 448

  Fly   598 KSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQAN----------DGLE---------QTN 643
            :....:.|......:...:...:|:..:|.... :.:||          |||.         :..
 Frog   449 RRQQKMQGKTVLLTDVAKQECSEDEEEIAPNNT-ESEANTRPDDEVPTADGLNTMKSDLSALENG 512

  Fly   644 GQTEDSTTSSVTTSEHSDADVEDNLVEDTAAPSTNNVPSSTASLTAPSKTYMDSNGNAQPPGEKR 708
            .:..:|....||    .|.|:      ||:..:|.:|..:...|..    .|::|.|......|
 Frog   513 SEAIESAMERVT----EDTDI------DTSGHNTESVEMNAMELVG----NMENNNNNNTDVNK- 562

  Fly   709 DDTPEHMDKDSLEEDENDSGIATSPAPTATNSSTSTSATGNNN--------SVAGSGLSGSSGAL 765
                      :||..|...|          :|..:|:|..|.|        :.|.:||...|.|.
 Frog   563 ----------TLERTEGSGG----------DSMEATAAVDNGNADTVCVDDTEAANGLLDCSAAS 607

  Fly   766 EDPLAPASLVTAGLSEKGASVIRQVSVGAEQGASNGTEDADGEAKAIEQPEKTPSQAQAMAQAQA 830
            .|.....||....||                        :|.|...:| .|..|.|.|...|...
 Frog   608 MDNELTNSLNRLKLS------------------------SDIEPTQVE-IEILPDQQQPHTQIYE 647

  Fly   831 RTKRVRTQSYSDWSTTIAPRYQCEDGECSVQSCLNNFTAVELMTGQNKVGCDSCTQ----RINGS 891
            ........::|    |::.|........||.|||..||..|.:||.||:.|:.||:    |:|.|
 Frog   648 VINEDPKTAFS----TLSERKDLPLDGYSVLSCLYQFTHKETLTGNNKLLCNVCTRKQASRLNNS 708

  Fly   892 DP-KAKSVNTNATKQLLVSSPPAVLILHLKRFQLGPRCIFRKLTRPVSYPNLLDIAAFCGSKVKN 955
            :. :.|.|.|||.||:|||.|..:|.|||||||.....: ||:.|.:.:|.:||:|.||.||.||
 Frog   709 NKGEKKFVYTNAKKQMLVSDPSPILTLHLKRFQQNGFNL-RKINRHIKFPEVLDLAPFCTSKCKN 772

  Fly   956 LPNIDRKQKKLLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQL 1020
            :|   ..:.:|||:||||:||||.|..|||||:||:|   .|..:..:.:..|...|:
 Frog   773 IP---AGESRLLYSLYGVIEHSGSMRSGHYTAFVKLR---RPNQQLCEMVLKGVIPEV------- 824

  Fly  1021 KKLEELLAKEKAREQHLKVLDDSDDFSNSSSNSSTSDESQTPATPLEEQQTQQAQQPQQPQQLEE 1085
                                                                ...:|.|
 Frog   825 ----------------------------------------------------SGSEPGQ------ 831

  Fly  1086 AANVRAPPGKWYYVSDSRVQEVSEDTALKAQAYLLFYERI 1125
                    |.||::|||.||.||....|.:|||||||||:
 Frog   832 --------GSWYHISDSHVQAVSLSRVLSSQAYLLFYERM 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464	25/51 (49%)
		UBP12	<307..990	CDD:227847	217/725 (30%)
		Peptidase_C19	307..>512	CDD:470612	77/212 (36%)
		Peptidase_C19K	<849..1123	CDD:239132	94/278 (34%)
usp16	NP_001072158.1	zf-UBP	45..120	CDD:460464	30/89 (34%)
		UBP12	<120..862	CDD:227847	265/1007 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..196		12/64 (19%)
		Peptidase_C19	197..>426	CDD:470612	83/271 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	397..497		24/134 (18%)
		Peptidase_C19K	<663..861	CDD:239132	94/277 (34%)