Protein Alignment Usp16-45 and Usp1

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_651687.3
• Gene: Usp1 / 43462
• FlyBaseID: FBgn0028476
• Length: 1078
• Species: Drosophila melanogaster
• Alignment Length: 1085
• Identity: 197/1085 - (18%)
• Similarity: 321/1085 - (29%)
• Gaps: 381/1085 - (35%)

  Fly   289 LLTLETPRIE--NERLPRVRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGG-- 349
            :||.:||::.  .:|..||          :....::|.:        |:...||..:..|.||
  Fly    85 VLTADTPKLSPVKKRQRRV----------YVADTLRCYS--------LRSRQEPATKDPLEGGLK 131

  Fly   350 -TFTIKDKGDIELPMIKGTLSS------------WGGLTAALANALEELQ----AGGSVFTP--- 394
             ...:.....::.|....|.|:            |        |.:||.|    .|....||
  Fly   132 QPDVVPPPPPVQAPSPTPTESTEYTPPEQFKSEFW--------NRIEEAQEPKPVGKKRRTPGGL 188

  Fly   395 -----RKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLK------RYQRVILQNLGYKDQ 448
                 .||...|.::.|:..........||         |...|      |..|.....:...|:
  Fly   189 KRTRGNKLLKELEIQSPETAAAIAAAQAEL---------NAAGKSGAAGARSSRKRTNTMSLYDR 244

  Fly   449 DVNSVSEEMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEK 513
            ...:.:|| |:....||..|...:                     ..||.:|        :..::
  Fly   245 RFQTTTEE-RRVANGYGGNAARSV---------------------TGSSSNE--------IESQE 279

  Fly   514 PQPPQRRKPSPELSLTSSSSSVTPSTG----QPTINTKFTDG------SVNFTASSPSFFLH-AH 567
            ||..|...|:...:...:.:.:..|..    .|::.|....|      ||.:|......||| .|
  Fly   280 PQSHQYYGPNGGSNAAGAGAGLNGSAAALNHAPSMGTLCNIGNSCYLNSVVYTLRFAPHFLHNLH 344

  Fly   568 EAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGD 632
            .   |....:.|::...||:.|:.|:..:..|:..|....|.:..:||.|.||.......:.:|:
  Fly   345 H---LIQDLNVVQQTIVRQQTARSASLGKNVSAAQLEHARSWSSKDLATSTDQYSGQNGGVNSGN 406

  Fly   633 GQANDGLEQTNGQTEDSTTSSVTTSEHSDADVEDNLVEDTAAPSTNNVPSSTASLTAPSKTYMDS 697
            |.:.         :..||..|||...|   ::.:||       ..|.:..||....|.:..:...
  Fly   407 GGSG---------SSKSTHQSVTEKLH---ELYNNL-------HGNEMADSTEPYHADTLLHAIQ 452

  Fly   698 NGNAQPPGEKRDDTPEHM---------DKDSL-----------------EEDENDSGIATSPAPT 736
            :.||...|.::.|..|.:         ...||                 ..||.|:|    ....
  Fly   453 DVNATFEGNQQQDAHEFLMCVLNCIRETNQSLIKAIGECPEVIANGYIANPDEVDTG----EGQD 513

  Fly   737 ATNSSTSTSATGNNNSVAGSGLS-------------------GSSGALEDPLAPASLVTAGLSEK 782
            .|:|:.|.:....|.|:|.|..:                   ..|..::.||...|....|::..
  Fly   514 RTDSTASQNLNAGNGSLATSQTTTTKTSFFSRKSKRKDEVKPSKSTRVQSPLKENSPTAGGITGA 578

  Fly   783 G-----ASVIRQVSVGAEQGASNGTEDADGEAKAIEQPE---KTPSQA------QAMAQAQARTK 833
            |     |:.:..::.....|||:.:..|...|..:....   .||.||      ..|..|.....
  Fly   579 GTAHATANSLFYLNTVDLSGASSTSGSASTSASGVVSTSAALPTPPQATKYSSDDEMNSATVLKD 643

  Fly   834 RVRTQS----------YSDWSTTIAPRYQC---------EDGECSV------------------- 860
            ::|.:.          .||:...:....:|         :.|...:
  Fly   644 KMRLEERIRELNLNFFSSDFEGIVVLTTKCLSCETITRQKQGMLDISVPVPISGYDNADLQDKPS 708

  Fly   861 ----QSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPKAKSVNTNATKQLLVSSPPAVLILHLKR 921
                .||:..    |...|:||..|:.||.            .|.|.:.:.....|.:|::.|.|
  Fly   709 TYIQNSCITK----EYFRGENKYSCNQCTG------------YTEAIRSISYEVLPRLLVIQLNR 757

  Fly   922 FQLGPRCIFRKLTRPVSYPNLLDIAAFCGSKVKNLPNIDRKQKKLLYALYGVVEHSGG-MYGGHY 985
            |..|    ..|::..|  |....:..||.:..:    :....|..:|.||.|:.|.|. :..|||
  Fly   758 FSGG----MEKVSTYV--PTTFTLPCFCATCCE----LGEGNKLHVYKLYSVITHVGATLTVGHY 812

  Fly   986 TAY-------------------------------VKVRPKVAPGD-------------------- 999
            .||                               |......||.:
  Fly   813 IAYTCFLDLASDYVNCPKDRRNTMTNSQTMASQAVPSNENAAPNNGSSSVASTPVIAAASALASS 877

  Fly  1000 -----KRWKFLPHGSKAELDQD-DDQLKKLEELLAK----------------------------- 1029
                 |:.||  ..|||....| ...:|::..:::|
  Fly   878 GNILMKKMKF--GRSKASSSGDMSKNVKQVNGIISKNITNGIGKLSISTTCQGVNCCAMRLCCTQ 940

  Fly  1030 EKAREQHLKVLDDSDDFSNSSSNSSTSDESQTPATPLEEQQTQQAQQPQQPQQLEEAANVRA--- 1091
            :.:........|.|::...:.|||:.|........|.....|.:             ..|||
  Fly   941 QTSSSNSTSCSDFSEESLQNGSNSNLSFGGSGSTYPTGYGSTGR-------------GGVRANYA 992

  Fly  1092 ---PPGKWYYVSDSRVQE---------VSEDTALKAQAYLLFYER 1124
               |...||...|.:::.         :|....:....|||||.|
  Fly   993 HGGPDPIWYMCDDDKIKAMTQREFEELLSPTRKITITPYLLFYAR 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464
		UBP12	<307..990	CDD:227847	156/859 (18%)
		Peptidase_C19	307..>512	CDD:470612	38/237 (16%)
		Peptidase_C19K	<849..1123	CDD:239132	68/407 (17%)
Usp1	NP_651687.3	Peptidase_C19	308..819	CDD:470612	113/562 (20%)