Protein Alignment Usp16-45 and puf

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_001262923.1
• Gene: puf / 42935
• FlyBaseID: FBgn0039214
• Length: 3930
• Species: Drosophila melanogaster
• Alignment Length: 844
• Identity: 164/844 - (19%)
• Similarity: 257/844 - (30%)
• Gaps: 276/844 - (32%)

  Fly   129 EHYQTPHSDSHALAMNTRSFDIWCYECDMKICSNLRKNLLECVELVKKLAQKPPTSTVTPSTPTI 193
            |:|:..|.                |:.|         .|:..:.|:..|.:...|...||.  .:
  Fly  1894 EYYELRHG----------------YQDD---------GLVGLLNLMSNLIKYDTTFKYTPK--AL 1931

  Fly   194 SYIEEKLKAALEHLTPIVPMTGGSFDDSSSRGSLAAAGGGGGVGSSRNRQVAIPMPPP------- 251
            |:||:              :.|..||                            ||.|
  Fly  1932 SFIEQ--------------LIGFLFD----------------------------MPSPADRQKPK 1954

  Fly   252 --EPSSGLSTSDSLTSV-PGMAKRIDQYSATTNGNTGNKRLLTLET------------PRIENER 301
              ..||..|..|.|..: .|.|         ||....:.|||....            ||.|...
  Fly  1955 CKSASSRASAYDLLVELCRGCA---------TNYAYLHGRLLAQHKSGPKQPYPWDYWPRDEGRA 2010

  Fly   302 LPRVRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMIKG 366
            .....||||||.||:..:.:|.|...|...:.:  |..|.......|.|.       :||..:..
  Fly  2011 ECGYVGLTNLGATCYMASCVQHLYMMPQARAAV--LRVPPNAARKHGPTL-------LELQRMFA 2066

  Fly   367 TLSSWGGLTAALANALEELQAGGSVFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRN-- 429
            .|                |::....:.||.......:.......|:|.|..|....|:..:.:
  Fly  2067 YL----------------LESERKSYNPRSFCRVYQMDHQPLNTGEQKDMAEFFIDLVSKLEDMT 2115

  Fly   430 EDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHN 494
            .|||...:                                       ::|.|.|.:.:...||.:
  Fly  2116 PDLKHLVK---------------------------------------RLFCGSLSNNVVSLDCGH 2141

  Fly   495 VSSRHEYFLDMSLPVAVEKPQPPQRRKPSPELSLTSSSSSVTPSTGQ-------------PTI-- 544
            ||...|.|..:...||..:.......:.:.:.:|...:.......|:             |.|
  Fly  2142 VSRTAEDFYTVRCQVADMRNLQESLDEVTVKDTLEGDNMYTCSQCGKKVRAEKRACFKKLPQILC 2206

  Fly   545 -NT-KFT-------DGSVNFTASSPSFFLHAHEA-ASLGPSKSQVKKEKERQRKAKRAAKKRQKS 599
             || ::|       ...||...|.|......|.. .:|.|  .|.|:|:||::|.|..|
  Fly  2207 FNTMRYTFNMVTMLKEKVNTHFSFPLRLNMCHYVEKTLMP--QQYKEERERRQKEKEGA------ 2263

  Fly   600 SLNLNGNDSGNGNELAESVDQDDA------SLASLGAGDGQANDGLEQTNGQTEDSTTSSVTTSE 658
                :|:..||.||.||:...||.      .|..:....|.|:.|  ......::.|.:|..|.|
  Fly  2264 ----DGSGDGNDNEKAEATLDDDIEECYEYELVGVTVHTGTADGG--HYYSFIKERTKTSYHTHE 2322

  Fly   659 H----SDADVEDNLVEDTAAPSTNNVPSSTASLTAPSKTYMD-----SNGNAQPPGEKRDDTPEH 714
            .    :||:|:.......||.......:| .:..:.::.|:|     :|.......|:|  .|||
  Fly  2323 RWFLFNDAEVKPFDPSQIAAECFGGEMTS-KTYDSVTEKYLDFSFEKTNSAYMLFYERR--LPEH 2384

  Fly   715 MDKDSLEEDENDSGIATSPAPTATNSSTSTSATGNNNSVAGSGLSGSSGALEDPLAPASLVTAGL 779
                 |:...::..:..:|:||....|.:..                         |..:.|:.
  Fly  2385 -----LQRRHSELLVTPTPSPTVEEKSEAEE-------------------------PTKMETSS- 2418

  Fly   780 SEKGASVIRQVSVGAEQGASNGTEDADGEAKAIEQPEKTPSQAQAMAQAQARTKRVRTQSYSDWS 844
            ||..|.|  .|.|..|:.........|.|:|  |.|.|.........|.:...|::..||
  Fly  2419 SEIKADV--DVEVEVEEKDKEKPAQTDTESK--ETPAKEEIADDKSKQDEPEEKKIEKQS----- 2474

  Fly   845 TTIAPRYQCEDGECSVQSCLNNFTAVELMTGQNK---VGCDSCTQRINGSDPKAKSVNTNATKQ 905
                     .:||...::.........:.|.:.|   ..||: .|:.|.|:.||.:....:|.:
  Fly  2475 ---------REGEEKSETDEKPTEMTTVSTEEEKQPTANCDN-HQQNNNSNSKASNDQQPSTSK 2528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464	5/29 (17%)
		UBP12	<307..990	CDD:227847	129/644 (20%)
		Peptidase_C19	307..>512	CDD:470612	40/206 (19%)
		Peptidase_C19K	<849..1123	CDD:239132	12/60 (20%)
puf	NP_001262923.1	peptidase_C19C	2013..2382	CDD:239124	90/449 (20%)
		DUF3517	2648..>2884	CDD:463438
		MDN1	<3661..>3887	CDD:444083