Protein Alignment Usp16-45 and usp20

DIOPT Version :9

• Sequence 1: NP_001284890.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: XP_009299732.1
• Gene: usp20 / 393962
• ZFINID: ZDB-GENE-040426-1219
• Length: 944
• Species: Danio rerio
• Alignment Length: 1140
• Identity: 212/1140 - (18%)
• Similarity: 321/1140 - (28%)
• Gaps: 488/1140 - (42%)

  Fly    16 TDSGNEDLHHRKGLGSPGQSDGATPTTASCQHIKKAVDAARLRRLLKSTGLLYECSQCQKLGKTA 80
            ||||  ||                     |.|:....:..:...:.||.|   .|..|
Zfish    35 TDSG--DL---------------------CPHLDSIGEVTKEELIQKSKG---TCQSC------- 66

  Fly    81 GSAAGAGASEGAVGPGGNPVTFEFDNTLWLCLKCGSQL--CGRARHKHALEHYQTPHSDSHALAM 143
                      |..||           .||.||:|....  ||.:...|:..|.|   :..|.|.:
Zfish    67 ----------GVGGP-----------NLWACLQCDCPYVGCGESYSDHSTIHAQ---AKKHNLTV 107

  Fly   144 NTRSFDIWCYECDMKICSNLRKNLLECVELVKKLAQKPPTSTVTPSTPTISYIEEKLKAALEHLT 208
            |..:|.:|||.|:.::                                   ::|.|
Zfish   108 NLTTFRVWCYVCEREV-----------------------------------FLEPK--------- 128

  Fly   209 PIVPMTGGSFDDSSSRGSLAAAGGGGGVGSSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRI 273
            |:.|:                        ||.:|    ..|..:.....:|...|.:||...
Zfish   129 PVTPV------------------------SSAHR----CKPHDQDPVSQTTCYPLKAVPIAV--- 162

  Fly   274 DQYSATTNGNTGNKRLLTLETPRIENERLPR-VRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKEL 337
                |...|:...           |:|..|| :.|:.|:||:|:.||.:|.|:..|.|....::.
Zfish   163 ----ADEEGSESE-----------EDELKPRGLTGMKNIGNSCYMNAALQALSNCPPLTQFFQDC 212

  Fly   338 SEPGEEFILPGGTFTIKDKGDIELPMIKGTLSSWGGLTAALANALEEL--QAGGSVFTPRKLFDR 400
            |         |...|.|..                .|..:....:.||  :...|...|..||..
Zfish   213 S---------GLVRTDKKP----------------ALCKSYQKLISELWHKKRPSYVVPTTLFHG 252

  Fly   401 LCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYG 465
            :.:..|.|.|..|.|..|.||.|::.: :|:||.                           .::.
Zfish   253 IKLVNPMFRGYAQQDTQEFLRCLMDQL-HEELKE---------------------------PLFD 289

  Fly   466 NQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEKPQPPQRRKPSPELSLTS 530
            ...|...:.|:          |:...|:.|..                     .|.||.:..|:.
Zfish   290 CSGGISEVEPD----------LSLDSCNLVDG---------------------DRSPSEDEFLSC 323

  Fly   531 SSSSVTPSTGQPTINTKFTDGSVNFTASSPSFFLHAHEAASLGPSKSQVKKEKERQRKAKRAAKK 595
            .|.|          .::..||.   .|...:..|...|..::..:....:||:.::|:.:...:
Zfish   324 DSGS----------GSERGDGE---RAGGEAELLIQDECVAVRGTGGISEKERLKERRGEERTR- 374

  Fly   596 RQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQANDGLEQTNGQTEDSTTSSVTTSEHS 660
                             |:.|..|.|.|      |.||||       ..:||.:|.:
Zfish   375 -----------------EMDEDADVDTA------AQDGQA-------ERETETATPA-------- 401

  Fly   661 DADVEDNLVEDTAAPSTNNV-PSSTASLTAPSKTYMDSNGNAQPPGEKRDDTPEHMDKDSLEE-- 722
                       ||.|:..|. |.:.||:..||               .|..:|.|    |::|
Zfish   402 -----------TAVPAPGNTEPDNEASMHCPS---------------SRPCSPAH----SVQELH 436

  Fly   723 ------DENDSGIATSPAPTATNS----STSTSATGNNNSVAGSGLSGSSGALEDPLAPASLVTA 777
                  ....|.:.|.|..|...:    ||.........||......||.      |:....:|.
Zfish   437 SRLSSNPPRSSPLRTGPTYTFKKAQMLLSTKKKKQSRFRSVISDIFDGSI------LSLVQCLTC 495

  Fly   778 GLSEKGASVIRQVSVGAEQGASNGTEDADGEAKAIEQPEKTPSQAQAMAQAQARTKRVRTQSYS- 841
            ..........:.:|:...     |.||......:|.|  ..|.:|           .|.|..|:
Zfish   496 DRVSTTVETFQDLSLPIP-----GKEDLAKLHSSIHQ--SAPVKA-----------GVCTDGYAA 542

  Fly   842 -DWSTTIAPRYQCEDGEC----------SVQSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPKA 895
             .|.:.|....:.....|          :::.||..|.|.:.:.|.|...|:.|.:..||
Zfish   543 QGWISYIMDSIRRFVVSCIPSWFWGPMVTLEDCLAAFFAADELKGDNMYSCERCKKLRNG----- 602

  Fly   896 KSVNTNATKQLLVSSPPAVLILHLKRFQLGPRCIFRKLTRPVSYP-NLLDIAAFCGSKVKNLPNI 959
                   .|...|...|.:|.:|||||:......| |:...||:| ..||:..|.   .|..|:
Zfish   603 -------VKYCKVLRLPEILCIHLKRFRHEVMYSF-KINSHVSFPLEGLDLKPFL---AKESPS- 655

  Fly   960 DRKQKKLLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQLKKLE 1024
                :...|.|..|:.|.|....|||.||.:
Zfish   656 ----QITTYDLLSVICHHGTAGSGHYIAYCQ---------------------------------- 682

  Fly  1025 ELLAKEKAREQHLKVLDDSDDFSNSSSNSSTSDESQTPATPLEEQQTQQAQQPQQPQQLEEAANV 1089
                         .|::
Zfish   683 -------------NVIN------------------------------------------------ 686

  Fly  1090 RAPPGKWYYVSDSRVQEVSEDTALKAQAYLLFYER 1124
                |:||...|..|.||.|.....|:||:|||.:
Zfish   687 ----GQWYEFDDQYVTEVHETVVQNAEAYVLFYRK 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_001284890.1	zf-UBP	108..159	CDD:280334	18/52 (35%)
		Peptidase_C19	307..>512	CDD:271592	39/206 (19%)
		Peptidase_C19K	<849..1123	CDD:239132	54/284 (19%)
usp20	XP_009299732.1	zf-UBP	63..123	CDD:280334	23/90 (26%)
		UCH	180..715	CDD:278850	158/844 (19%)
		Peptidase_C19	180..>285	CDD:271592	33/130 (25%)
		Peptidase_C19R	476..716	CDD:239139	73/383 (19%)
		DUSP	737..818	CDD:197831
		DUSP	843..927	CDD:197831

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5560
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900