Protein Alignment Usp16-45 and Usp47

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_523937.2
• Gene: Usp47 / 38644
• FlyBaseID: FBgn0016756
• Length: 1556
• Species: Drosophila melanogaster
• Alignment Length: 898
• Identity: 169/898 - (18%)
• Similarity: 260/898 - (28%)
• Gaps: 375/898 - (41%)

  Fly   390 SVFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRY----QRVILQNLGYKDQDV 450
            |.||.:::.|.:         |.|. ::|....||:...|:||...    .:::.:..|::.|..
  Fly    31 SHFTVKRVIDLI---------GTQF-SYEKFELLLQPHDNKDLVNLNALESQLMYEVAGFEPQLK 85

  Fly   451 NSVSEEMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEKPQ 515
            |.:                  ||.|...:.|            :|:.|.|      ||:
  Fly    86 NHL------------------ILLPSGSWDG------------DVTKRFE------LPI------ 108

  Fly   516 PPQRRKPSPELSLTSSSSSVTPSTGQ-------PTINTKFTDGSVNFTASSPSFFLHAHEAASLG 573
               :|....::..:....:.:|:||:       .....|...||     ||||   .|...:...
  Fly   109 ---KRVVVKKVMKSDGEKAKSPATGEKKKRVVGEKTKKKPASGS-----SSPS---KAKTTSEDS 162

  Fly   574 PSKSQVKKEK--ERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQAN 636
            .:|:.:..|.  |:..|.|..|.|..|.           |:|.|.....::.
  Fly   163 LAKTSISSESSPEKTSKIKTTAAKISKP-----------GSEKAPRASPEEC------------- 203

  Fly   637 DGLEQTNGQTEDSTTSSVTTSEHSDADVEDNLVEDTAAPSTNNVPSS-TASLTAP---------- 690
               .:.:.:.....|||                |...|..|..|.|. |..|.:|
  Fly   204 ---PELSTEINSKNTSS----------------ESPVAKKTAKVTSKPTLELLSPIKPSSPIKEL 249

  Fly   691 --------SKTYMDSNGNAQPPGEKR----DDTPEHM---DKDSLEEDENDSGIATSP------- 733
                    ||..:.......|.|...    ||.|..:   |.:.|.:|:...|.:.||
  Fly   250 DCEPVDTLSKQQLSEQLQLYPQGRNLISPVDDAPSDLFISDAEQLSDDDLALGASASPTMLGPGY 314

  Fly   734 ---APTATNSSTSTSATG-NNNSVAGSGLSGSSGALE---------DPL--------APASLVTA 777
               ||  |..|.....|| .:.|..|:. .|:..||.         |.|        ..|..|::
  Fly   315 DYGAP--TGDSDVEGVTGVTDPSTIGTD-DGTYPALSNFYRRKYGGDELRAWQRVNTTGADFVSS 376

  Fly   778 GLSEKGASVIRQVSVGAE--QGASNGTE--------------------------DADGEAK---- 810
            ..:|..|.. ||.|:|..  .|..|...                          |.|.|||
  Fly   377 ATTETEAEA-RQASLGPRGYVGLVNQAMTCYLNSLLQALFMTPEFRNALYRWEFDNDNEAKNIPY 440

  Fly   811 ------------------------------------------------AIEQPEKTPSQAQAMAQ 827
                                                            |:|...|...||..::.
  Fly   441 QLQKLFLNLQTSPKAAVETTDLTRSFGWDSTEAWQQHDIQELCRVMFDALEHKFKNTKQANLISN 505

  Fly   828 ------------AQARTKRVRTQSYSDWSTTIAPRYQCEDGECSVQSCLNNFTAVELMTGQNKVG 880
                        .:..|::.|..::.|....:.| :.......|::..|..|...|.:.|.|:..
  Fly   506 LYEGKMNDYVKCLECNTEKTREDTFLDIPLPVRP-FGSSSAYGSIEEALRAFVQPETLDGNNQYL 569

  Fly   881 CDSCTQRINGSDPKAKSVNTNATKQLLVSSPPAVLILHLKRFQLGPRCIFR-KLTRPVSYPNLLD 944
            |:.|.::            .:|.|.|...|.|.:|.||||||....:.:.| ||...|::|..|:
  Fly   570 CEKCKKK------------CDAHKGLHFKSFPYILTLHLKRFDFDYQTMHRIKLNDRVTFPQTLN 622

  Fly   945 IAAF--------------------C-----GSKVK--NLPN---------------------ID- 960
            :..|                    |     ||.::  ||.:                     ||
  Fly   623 LNTFINRSGNSGEQNSQLNGTVDDCSTADSGSAMEDDNLSSGVVTTASSSQHENDLNDEDEGIDM 687

  Fly   961 ----RKQKK-----LLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQD 1016
                .|..|     .||.|:.::.|||...||||.||:|     ...:..|......:...:.|:
  Fly   688 SSSTSKSAKQGSGPYLYELFAIMIHSGSASGGHYYAYIK-----DFDNNEWFCFNDQNVTSITQE 747

  Fly  1017 DDQLK-----------------------------KLEELLAKEKAREQHLKVL 1040
            |.|..                             |..||:||.....:|:|.|
  Fly   748 DIQRSFGGPNGSYYSSAYTSSTNAYMLMYRQVDAKRNELVAKVADFPEHIKTL 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464
		UBP12	<307..990	CDD:227847	156/817 (19%)
		Peptidase_C19	307..>512	CDD:470612	24/125 (19%)
		Peptidase_C19K	<849..1123	CDD:239132	62/280 (22%)
Usp47	NP_523937.2	DUF4045	<122..249	CDD:433066	33/177 (19%)
		peptidase_C19C	394..780	CDD:239124	69/403 (17%)
		USP47_C	1300..1534	CDD:466158