Protein Alignment Usp16-45 and Usp5

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_647773.1
• Gene: Usp5 / 38375
• FlyBaseID: FBgn0035402
• Length: 827
• Species: Drosophila melanogaster
• Alignment Length: 848
• Identity: 173/848 - (20%)
• Similarity: 260/848 - (30%)
• Gaps: 309/848 - (36%)

  Fly     4 KRQADSRDHDCSTDSGNEDLHHRKGLGSPG---QSDGA-------TPTTASCQHIKKAV---DAA 55
            |..||.......:::|.|....|..:|..|   :||.|       |.:.....|:.|.:   |..
  Fly    79 KEGADMEAECAESEAGPERKITRLAIGVEGGYNESDMAKKYEIKDTYSIVVAPHLDKKLPYPDPE 143

  Fly    56 RLRRLLKST-GLLYECSQCQKLGKTAGSAAGAG----ASEGA-----------VGPGG-NPVTFE 103
            ...|:.:|. .:|...|...||.|........|    ||:.|           :.|.| .....:
  Fly   144 LPMRVTQSVEAILAADSAIAKLEKATLMGTWDGEVRQASKYADNLQQLDNGKRIPPSGWQCEKCD 208

  Fly   104 FDNTLWLCLKCGSQLCGR------ARHKHALEHYQTPHSDSHALAMNTRSFDIWCYECDMKICSN 162
            ..|.|||.|..||.:|||      ..:.||:|||:            ...|
  Fly   209 LTNNLWLNLTDGSIMCGRKFFDGSGGNDHAVEHYR------------VTGF-------------- 247

  Fly   163 LRKNLLECVELVKKLAQKPPTSTVTPSTPTISYIEEK--LKAALE-HLTPIVPMTGGSFDDSSSR 224
                         .||.|..|.|....:...||.|::  |...|| ||              |..
  Fly   248 -------------PLAVKLGTITADGKSDVFSYPEDEMVLDPHLERHL--------------SHF 285

  Fly   225 GSLAAAGGGGGVGSSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGNTGNKRL 289
            |...||     :..|....|.:.:                   .:.:||.:::|.|...:
  Fly   286 GINMAA-----MKKSEKSMVELEL-------------------DINQRIGEWTALTESES----- 321

  Fly   290 LTLETPRIENERLPRVRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIK 354
                  .::....|...|:.||||:|:.|:|||.|...|          :..:.|:..|.....|
  Fly   322 ------ELQPVAGPGYTGMRNLGNSCYINSVMQVLFVIP----------DFQQRFVGTGAERYFK 370

  Fly   355 D-----KGDIELPMIK-GTLSSWGGLTAALANALEELQAGGSVFTPRKLFDRLCVKCPQFTGGDQ 413
            :     ..|..:.|.| ||....|..::...|.|:...:.|  .:|....:.:....|.|:...|
  Fly   371 EFPSDPANDFNIQMAKLGTGLQSGKYSSIAENTLDTDHSTG--ISPAMFKNIVGKNHPDFSTKQQ 433

  Fly   414 HDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPEQV 478
            .||::....||..:                     |.||            .||.     .|...
  Fly   434 QDANDFYLHLLTLL---------------------DRNS------------RNQT-----NPADA 460

  Fly   479 FRGFLVSTLTCQDCHNV--SSRHEYFLDMSLPVAVEKP-------QPPQRRKPS----------- 523
            .:..|...:.|...|.|  ::|.||  ...|||.::|.       :..:|:|.:
  Fly   461 LKFLLEDRVECLASHKVKYNTREEY--SFRLPVPLDKATNLDEVREFQERKKAARETGQRLPDRD 523

  Fly   524 -----------------PELSLTSSSSSVTPSTGQPTINT-------------KFTDG------S 552
                             |||.....|:::...|....|..             |||.|      .
  Fly   524 IVRHKVPLQACLERFFGPELIEQFYSTAIGSKTNARKITRLATMPDCLMIHVGKFTLGDDWVPKK 588

  Fly   553 VNFTASSPSFF----------LHAHEAASLGPSKSQVKKEKER------------QRKAKRAAKK 595
            ::.:...|...          |...|.|...|:..:||...:.            ....|||...
  Fly   589 LDVSVDMPDELDLSNWRSAGGLQPGEEALPEPATEEVKFAFDEAVMSELLTMGFPPEACKRACYH 653

  Fly   596 RQKSSLNLNGNDSGNGNELAESVDQDD---------------------------ASLASLGAGDG 633
            .:.|.|      ....|.|.|.:..:|                           |.|.|:|..:.
  Fly   654 TKNSGL------EAASNWLMEHIADEDISEPFVVPNNSIGDCAANQFVANPESLAMLMSMGFDER 712

  Fly   634 QANDGLEQTNGQTEDSTTSSVTTSEHSDA-DVEDNLVEDTAAPSTNNVPSSTASLTAPSKT-YMD 696
            ||...|:.|:|..|.:|.   ....|:|: .|||      |||:.|:  |:.|:.:.|:|| |.|
  Fly   713 QAVAALKATDGNVERATD---WIFSHADSIGVED------AAPAANS--SAAAASSTPNKTNYRD 766

  Fly   697 SNG 699
            ..|
  Fly   767 GRG 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464	15/56 (27%)
		UBP12	<307..990	CDD:227847	105/506 (21%)
		Peptidase_C19	307..>512	CDD:470612	48/212 (23%)
		Peptidase_C19K	<849..1123	CDD:239132
Usp5	NP_647773.1	zf-UBP_var	11..77	CDD:407678
		zf-UBP	204..278	CDD:460464	25/112 (22%)
		Peptidase_C19B	333..823	CDD:239123	105/506 (21%)
		UBA1_UBP5_like	631..674	CDD:270480	8/48 (17%)
		UBA2_UBP5	696..737	CDD:270569	12/43 (28%)