Protein Alignment Usp16-45 and Usp20

DIOPT Version :9

• Sequence 1: NP_001284890.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_001101297.1
• Gene: Usp20 / 311856
• RGDID: 1305621
• Length: 915
• Species: Rattus norvegicus
• Alignment Length: 1147
• Identity: 224/1147 - (19%)
• Similarity: 337/1147 - (29%)
• Gaps: 492/1147 - (42%)

  Fly    45 CQHIKKAVDAARLRRLLKSTGLLYECSQCQKLGKTAGSAAGAGASEGAVGPGGNPVTFEFDNTLW 109
            |.|:....:..:...||||.|   .|..|                 |..||           .||
  Rat     8 CPHLDSIGEVTKEDLLLKSKG---TCQSC-----------------GVAGP-----------NLW 41

  Fly   110 LCLK--CGSQLCGRARHKHALEHYQTPHSDSHALAMNTRSFDIWCYECDMKICSNLRKNLLECVE 172
            .||:  |....||.:...|:..|.|...   |.|.:|..:..:|||.|:.::
  Rat    42 ACLQVTCPYVGCGESFADHSSIHAQVKR---HNLTVNLTTLRVWCYACEREV------------- 90

  Fly   173 LVKKLAQKPPTSTVTPSTPTISYIEEKLKAALEHLTPIVPMTGGSFDDSSSRGSLAAAGGGGGVG 237
                                  ::|::|..   ||    |.:.....:..|
  Rat    91 ----------------------FLEQRLAV---HL----PSSSARLSEQDS-------------- 112

  Fly   238 SSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGNTGNKRLLTLETPRIENERL 302
                       |||        ...|.:||        .:....|          |:...:::..
  Rat   113 -----------PPP--------CHPLKAVP--------IAVADEG----------ESESEDDDLK 140

  Fly   303 PR-VRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMIKG 366
            || :.|:.||||:|:.||.:|.|:..|           |..:|.|..|.....||
  Rat   141 PRGLTGMKNLGNSCYMNAALQALSNCP-----------PLTQFFLECGGLVRTDK---------- 184

  Fly   367 TLSSWGGLTAALANALEEL------QAGGSVFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLE 425
                    ..||..:.::|      :...|...|..|...:.:..|.|.|..|.|..|.||.|::
  Rat   185 --------KPALCKSYQKLISEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMD 241

  Fly   426 SVRNEDLKRYQRVILQNL-GYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTC 489
            .: :|:||......:..| ..:|.| :|.::|.|.         ||
  Rat   242 QL-HEELKEPMVAAVAALTDARDSD-SSDTDERRD---------GD------------------- 276

  Fly   490 QDCHNVSSRHEYFLDMSLPVAVEKPQPPQRRKPSPELSLTSSSSSVTPSTGQPTINTKFTDGSVN 554
                                          |.||.:..|:..|||   ..|:       .||.
  Rat   277 ------------------------------RSPSEDEFLSCDSSS---DRGE-------GDGQ-- 299

  Fly   555 FTASSPSFFLHAHEAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVD 619
                            ..|...|:.:.|.....:|.||..::::..
  Rat   300 ----------------GRGGGSSKAEMELLISDEAGRAISEKERMK------------------- 329

  Fly   620 QDDASLASLGAGDGQANDGLEQTNGQTEDSTTSSVTTSEHSDADVEDNLVEDTAAPSTNNVPSST 684
                        |.:.:.|.::||.:..|           .||||      |||          .
  Rat   330 ------------DRKFSWGQQRTNSEQVD-----------EDADV------DTA----------M 355

  Fly   685 ASLTAPSKTYMDSNGNAQPPGEKRD---DTPE-----HMDKDS-----LEEDENDSGIATSP--- 733
            |||...|:       .||||..:..   .|||     |:...|     :...|..:.:::||
  Rat   356 ASLDEQSR-------EAQPPSPRPTSPCQTPEPDNEVHIRSSSRPCSPVHHHEGHTKLSSSPPRA 413

  Fly   734 -----APTATNSSTSTSATGNN-------NSVAGSGLSGSSGALEDPLA------------PASL 774
                 .|:.........:||..       .||.....:||..:|...|.            ..||
  Rat   414 SPVRMGPSYVLKKAQVPSTGGRRRKEQSYRSVISDVFNGSVLSLVQCLTCDRVSTTVETFQDLSL 478

  Fly   775 VTAGLSE--KGASVIRQVSVGAEQGASNGTEDADG-EAKAIEQPEK-----TPSQAQAMAQAQAR 831
            ...|..:  |..|.|.| :|.|:.||...:..:.| .|..:|...:     |||..
  Rat   479 PIPGKEDLAKLHSAIYQ-NVPAKPGACGDSYSSQGWLAFIVEYIRRFVVSCTPSWF--------- 533

  Fly   832 TKRVRTQSYSDWSTTIAPRYQCEDGECSVQSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPKAK 896
                       |...:           :::.||..|.|.:.:.|.|...|:.|.:..||
  Rat   534 -----------WGPVV-----------TLEDCLAAFFAADELKGDNMYSCERCKKLRNG------ 570

  Fly   897 SVNTNATKQLLVSSPPAVLILHLKRFQLGPRCIFRKLTRPVSYP-NLLDIAAF----CGSKVKNL 956
                  .|...|...|.:|.:|||||:......| |::..||:| ..||:..|    |.|:|..
  Rat   571 ------VKYCKVLCLPEILCVHLKRFRHEVMYSF-KVSSHVSFPLEGLDLRPFLAKECTSQVTT- 627

  Fly   957 PNIDRKQKKLLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQLK 1021
                       |.|..|:.|.|....|||.||.:   .|..|  :|          .:.||..:.
  Rat   628 -----------YDLLSVICHHGTAGSGHYIAYCQ---NVING--QW----------YEFDDQYVT 666

  Fly  1022 KLEELLAKEKAREQHLK--VLDDSDDFSNSSSNSSTSDESQTPATPLEEQQTQQAQQPQQPQQLE 1084
            ::.|.:.      |:::  ||     |...||..:..          |.||.......|:|..|.
  Rat   667 EVHETVV------QNVEAYVL-----FYRKSSEEAMR----------ERQQVVSLAAMQEPSLLR 710

  Fly  1085 --------EAANVRA-----------------PPGKWYYVSD 1101
                    ...|..|                 ||.|::|:.|
  Rat   711 FYVSREWLNKFNTFAEPGPITNHTFLCPHGGIPPNKYHYIDD 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_001284890.1	zf-UBP	108..159	CDD:280334	17/52 (33%)
		Peptidase_C19	307..>512	CDD:271592	43/211 (20%)
		Peptidase_C19K	<849..1123	CDD:239132	65/285 (23%)
Usp20	NP_001101297.1	UBP14	<8..>260	CDD:227532	81/408 (20%)
		UCH	145..683	CDD:395355	163/802 (20%)
		DUSP	703..786	CDD:197831	10/50 (20%)
		DUSP	811..895	CDD:197831

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5560
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810