Protein Alignment Usp16-45 and Usp32

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: XP_011247292.1
• Gene: Usp32 / 237898
• MGIID: 2144475
• Length: 1618
• Species: Mus musculus
• Alignment Length: 1008
• Identity: 209/1008 - (20%)
• Similarity: 328/1008 - (32%)
• Gaps: 341/1008 - (33%)

  Fly   296 RIENERLPRVR---GLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPG-GTFTIKDK 356
            :|:..::|..:   ||:|||||||.|:.:||::.|           :|..::.:.| ..:.:...
Mouse   735 KIDRHKVPTEKGATGLSNLGNTCFMNSSIQCVSNT-----------QPLTQYFISGRHLYELNRT 788

  Fly   357 GDIELPMIKGTLSSWGGLTAALANALEELQAGGSV-FTPRKLFDRLCVKCPQFTGGDQHDAHELL 420
            ..|.:   ||.::...|      :.::||.:|... ..|.||...:....|:|.|..|.|:.|||
Mouse   789 NPIGM---KGHMAKCYG------DLVQELWSGTQKNVAPLKLRWTIAKYAPRFNGFQQQDSQELL 844

  Fly   421 RQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKCKIYGNQAGDRILRPEQ-----VFR 480
            ..||:.: :|||.|........|  ||.|.....|        ...:|.|..||..:     :|.
Mouse   845 AFLLDGL-HEDLNRVHEKPYVEL--KDSDGRPDWE--------VAAEAWDNHLRRNRSIVVDLFH 898

  Fly   481 GFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEKPQPPQRRKPSPELSLT-SSSSSVTPSTGQPTI 544
            |.|.|.:.|:.|.::|.|.:.|..:|||:.::...         .|.:| ......||......:
Mouse   899 GQLRSQVKCKTCGHISVRFDPFNFLSLPLPMDSYM---------HLEITVIKLDGTTPIRYGLRL 954

  Fly   545 N--TKFTDGSVNFTASSPSFFLHAHEAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLNGND 607
            |  .|:|.             |....:...|....|:...:......|...:..||..|:::|
Mouse   955 NMDEKYTG-------------LKKQLSDLCGLKSEQILFAEVHSSNIKNFPQDNQKVRLSVSG-- 1004

  Fly   608 SGNGNELAESVDQDDASLASLGAGDGQANDGLEQTNGQTEDSTTSSVTTSEHSDADVEDNLVEDT 672
                               .|.|        .|.....:..|..|.:.|             :.:
Mouse  1005 -------------------FLCA--------FEIPIPASPVSACSPIQT-------------DCS 1029

  Fly   673 AAPSTNNVPSSTASLTAPSKTYMDSNG---NAQPPGEKRDDT----PEHMDKDSLEEDENDSGIA 730
            ::||||.:.:.|.:...|...:: .||   ...|.|.:::.|    ..||  ..|.:|.....|.
Mouse  1030 SSPSTNGLFTLTTNGDLPRPIFI-PNGMPNTVVPCGTEKNVTNGIVNGHM--PPLPDDPFTGYII 1091

  Fly   731 TSPAPTATNSSTSTSATGNNNSVAGSGLSGSSGALEDPLAPASLVTAGLSEKGA---SVIRQVSV 792
            ..............|:..|..|:.|..|          :.|.::.|.......|   .|.|..|.
Mouse  1092 AVHRKMMRTELYFLSSQKNRPSLFGMPL----------IVPCTVHTRKKDLYDAVWIQVSRLASP 1146

  Fly   793 GAEQGASNGTEDADGEAKAIEQPEKTPSQAQAMAQAQARTKRVRTQSYS---------------- 841
            ...|.|||..:|.|                .:|......|.||..:..:
Mouse  1147 LPPQEASNHAQDCD----------------DSMGYQYPFTLRVVQKDGNSCAWCPWYRFCRGCKI 1195

  Fly   842 ----------------DWS-TTIAPRYQ------CEDGE------------CSVQSCLNNFTAVE 871
                            ||. |.:..|||      .|:.|            .::.|||..||:.|
Mouse  1196 DCGEDRAFIGNACIAVDWDPTALHLRYQTSQERVVEEHESVEQSRRAQAEPINLDSCLRAFTSEE 1260

  Fly   872 LMTGQNKV-GCDSCTQRINGSDPKAKSVNTNATKQLLVSSPPAVLILHLKRFQ-LGPRCIFRKLT 934
            .: |:|:: .|..|            ..:..|||:|.:...|.:||:|||||| :..|.|  |..
Mouse  1261 EL-GENEMYYCSKC------------KTHCLATKKLDLWRLPPILIIHLKRFQFVNGRWI--KSQ 1310

  Fly   935 RPVSYP-NLLDIAAF--------CGSK----------VKNLPNIDRKQKKLLYALYGVVEHSGG- 979
            :.|.:| ...|.:||        |..|          ...:|..|.|:..        ::.|.|
Mouse  1311 KIVKFPRESFDPSAFLVPRDPTLCQHKPLTPQGDDFSELRIPAGDVKKVD--------IQSSAGE 1367

  Fly   980 ------MYGGHYTAYVKVRPKVAPGDKR---------WKFLPHGSKAELDQDDDQLKKLEELLAK 1029
                  ......:|.|...||.:|...|         ....|:.|...|.::..:| :|.::.:|
Mouse  1368 EDVLLSKSPSSLSANVTSSPKGSPSSSRKSGASCPSSKNSSPNSSPRTLGRNKGRL-RLPQIGSK 1431

  Fly  1030 EKAREQHLKVLDDSDDFSNSSSNSSTSDE---------------------SQTP-ATPLEEQQT- 1071
            .|              .|||..|..||.|                     ||.. .|||:.:.|
Mouse  1432 NK--------------LSNSKENLDTSKENGAGQICELADTLNRRHVLGGSQPELVTPLDHEITL 1482

  Fly  1072 ---------------------QQAQQPQQPQQLEEAAN------------------------VRA 1091
                                 ..:::.....|.||..:                        .:.
Mouse  1483 ANGFLYEHEACGNGYSNGQLGNHSEEDSTDDQREETHSKPIYNLYAISCHSGILGGGHYVTYAKN 1547

  Fly  1092 PPGKWYYVSDSRVQEVSEDTALKAQAYLLFYER 1124
            |..|||..:||..:|:..|......||:||||:
Mouse  1548 PNCKWYCYNDSSCKELHPDEIDTDSAYILFYEQ 1580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464
		UBP12	<307..990	CDD:227847	165/781 (21%)
		Peptidase_C19	307..>512	CDD:470612	60/211 (28%)
		Peptidase_C19K	<849..1123	CDD:239132	84/396 (21%)
Usp32	XP_011247292.1	EFh	237..293	CDD:238008
		EF-hand_7	270..342	CDD:463900
		UBP12	518..1330	CDD:227847	159/733 (22%)
		UCH	<1245..1578	CDD:425685	78/370 (21%)