Protein Alignment Usp16-45 and Usp3

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: XP_006511173.1
• Gene: Usp3 / 235441
• MGIID: 2152450
• Length: 606
• Species: Mus musculus
• Alignment Length: 579
• Identity: 129/579 - (22%)
• Similarity: 195/579 - (33%)
• Gaps: 211/579 - (36%)

  Fly    33 GQSDGATPTTASCQHIKKAV------DAARLRRLLKSTGLLYECSQCQK--------LGKTAGSA 83
            |.:.|.|     |..:..||      .:|.||..|        |..|::        ||.....|
Mouse    16 GSARGRT-----CGGVGLAVPRGPDRQSAALRAQL--------CLDCRRASPFGLRFLGFPQAPA 67

  Fly    84 AGAGASEGAVGPGG-----NPVTFEFDNTL---------------------------WLCLKCGS 116
            :.|.....|:|...     .||..:|:|.|                           |:||.|.|
Mouse    68 SPAAPERTALGAAHLGVSLQPVRVKFENRLRAPKAPEKAANSCFGGAARVCRSNKSPWVCLTCSS 132

  Fly   117 QLCGRARHKHALEHY---QTP---HSDS-------HALAMNTRSFDIWCYECDMKICSNLRKNLL 168
            ..|||..:.||.:||   |.|   |..|       |.:.|:..|:..:||.||..:.::.:..|
Mouse   133 VHCGRYVNGHAKKHYEDAQIPLLNHKRSEKQEKAQHTVCMDCSSYSTYCYRCDDFVVNDTKLGL- 196

  Fly   169 ECVELVKKLAQKPPTSTVTPSTPTISYIEEKLKAALEHLTPIVPMTGGSFDDSSSRGSLAAAGGG 233
              |:.|::..|....|..|..       ..:.:..||:
Mouse   197 --VQKVREHLQNLENSAFTAD-------RHRKRKLLEN--------------------------- 225

  Fly   234 GGVGSSRNRQVAIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGNTGNKRLLTLETPRIE 298
                ||.|.::            |..:.|.|::          .||
Mouse   226 ----SSLNSKL------------LKVNGSTTAI----------CAT------------------- 245

  Fly   299 NERLPRVRGLTNLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGG------TFTIKDKG 357
                    ||.|||||||.||::|.|:.........|||  |..|  |..|      |:..:.:|
Mouse   246 --------GLRNLGNTCFMNAILQSLSNIEQFCCYFKEL--PAVE--LRNGKTAGRRTYHTRSQG 298

  Fly   358 DIELPMI----KGTLSSWGGLTAALANALEELQAGGSVFTPRKLFDRLCVKCPQFTGGDQHDAHE 418
            |..:.::    |...:.|.|...|              |:|..||..:....|.|.|..|.||||
Mouse   299 DSNVSLVEEFRKTLCALWQGSQTA--------------FSPESLFYVVWKIMPNFRGYQQQDAHE 349

  Fly   419 LLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEE-----MRQKCKIYGNQAGDRILRPEQV 478
            .:|.||:.:..|         ||. |:.....:::.:|     ...||.|.|   ...::  ..:
Mouse   350 FMRYLLDHLHLE---------LQG-GFNGVSRSAILQENSTLSASNKCCING---ASTVV--TAI 399

  Fly   479 FRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVE-KPQPPQRRKPSPELSLTSSSSSVT 536
            |.|.|.:.:.|..|...|.:.:.|||:||.:..: :.:..:.::..|..||.....|.|
Mouse   400 FGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFT 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464	24/90 (27%)
		UBP12	<307..990	CDD:227847	67/246 (27%)
		Peptidase_C19	307..>512	CDD:470612	62/219 (28%)
		Peptidase_C19K	<849..1123	CDD:239132
Usp3	XP_006511173.1	zf-UBP	117..191	CDD:460464	23/73 (32%)
		UCH	245..594	CDD:425685	68/274 (25%)