Protein Alignment Usp16-45 and Usp15

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_001420766.1
• Gene: Usp15 / 171329
• RGDID: 628795
• Length: 981
• Species: Rattus norvegicus
• Alignment Length: 1056
• Identity: 224/1056 - (21%)
• Similarity: 352/1056 - (33%)
• Gaps: 339/1056 - (32%)

  Fly   153 YECDMKICSNLRKNLLECVELVKKLAQKPPTSTVTPSTPTISYIEEKLKAALEHLTPIVPMTGGS 217
            |..::|:|.|...|.:    :.::.::.....|:......|..|.::.:|.|.:     .....:
  Rat   132 YLTELKLCENGNMNNV----VTRRFSKADTIDTIEKEIRKIFNIPDEKEARLWN-----KYMSNT 187

  Fly   218 FDDSSSRGS-LAAAG---GGGGVGSSRNRQVAIPMPPPEPSS-GLSTSDSLTSVPGMAKRIDQYS 277
            |:..:...| :..||   |...|...:|.....|..|..|.| |.|...:|..: ..:...:.|:
  Rat   188 FEPLNKPDSTIQDAGLYQGQVLVIEQKNEDGTWPRGPSAPKSPGASNFSTLPKI-SPSSLSNNYN 251

  Fly   278 ATTNGNTGNK----------RLLTLETPRIENERLPRVRGLTNLGNTCFFNAVMQCLAQTPFLLS 332
            ...|.|..|.          :......|...||: |.:.||:|||||||.|:.:|||:.||
  Rat   252 NINNRNVKNSNYCLPSYTAYKNYDYSEPGRNNEQ-PGLCGLSNLGNTCFMNSAIQCLSNTP---- 311

  Fly   333 VLKELSEPGEEFILPGGTFTIKDKGDIELPMIKGTLSSWGGLTAALANALEELQAGG-SVFTPRK 396
                   |..|:.|       .||...|| .....|...|.:..:.|..::::.:|. |..|||.
  Rat   312 -------PLTEYFL-------NDKYQEEL-NFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRA 361

  Fly   397 LFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRYQRVILQNLGYKDQDVNSVSEEMRQKC 461
            ...::....|||:|..|.|..|||..||:.: :|||.|.::.....|  ||.|        .:..
  Rat   362 FKTQVGRFAPQFSGYQQQDCQELLAFLLDGL-HEDLNRIRKKPYIQL--KDAD--------GRPD 415

  Fly   462 KIYGNQAGDRILRPE-----QVFRGFLVSTLTCQDCHNVSSRHEYFLDMSLPVAVEKPQPPQRRK 521
            |:...:|.:..|:..     .:|.|...|||.|.:|..:|...:.|..::||:       |.:::
  Rat   416 KVVAEEAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYLTLPL-------PMKKE 473

  Fly   522 PSPELSLTSSSSSVTPSTGQ---PTINTKFTDGSVNFTASSPSFFLHAHEAASLGPSKSQVKKEK 583
            .|.|:.|........|...:   |.|      |::....::.|       |.|..|:...:..:.
  Rat   474 RSLEVYLVRMDPLAKPMQYKVIVPKI------GNILDLCTALS-------ALSGVPADKMIVTDI 525

  Fly   584 ERQRKAKRAAKKRQKSSLNLNGNDSGNGNELAESVDQDDASLASLGAGDGQANDGLEQTNGQTED 648
            ...|..:..|.....||:                :::||..:             .|....:|||
  Rat   526 YNHRFHRIFAMDENLSSI----------------MERDDIYV-------------FEININRTED 561

  Fly   649 S-------------TTSSVTTSEHSDADVEDNLVEDTAAPSTN-----------------NVPSS 683
            :             ..||.|....|....:..|:   |.|..|                 .:.:.
  Rat   562 TEHVVIPVCLREKFRHSSYTHHTGSSLFGQPFLM---AVPRNNTEDKLYNLLLLRMCRYVKMSTE 623

  Fly   684 TASLTAPSKTYMDSNGNAQ-PPGEKRDDTPEHMDKDSLEEDENDSGIATSPAPTATNSSTSTSAT 747
            |.....|.:...|.|.|.. |.|...:.:|..|:.|  |.|:..|.....|:.. .||.:..|..
  Rat   624 TEETDGPLRCCEDQNINGNGPNGIHEEGSPSEMETD--EPDDESSQDQELPSEN-ENSQSEDSVG 685

  Fly   748 GNNNSVAG--------SGLSGSSGALEDPLAPASLVTAGLSEKGASVIRQVSVGAEQGASNGTED 804
            |:|:|..|        ..|:|..         ..|.|...:..|.:.|..:.
  Rat   686 GDNDSENGLCTEETCKGQLTGHK---------KRLFTFQFNNLGNTDINYIK------------- 728

  Fly   805 ADGEAKAIEQPEKTPSQAQAMAQAQARTKRVRTQSY--SDWSTTIAPRY----QCEDGE------ 857
              .:.:.|...:              |..|:..:|:  .||...:..||    ..||.|
  Rat   729 --DDTRHIRFDD--------------RQLRLDERSFLALDWDPDLKKRYFDENAAEDFEKHESVE 777

  Fly   858 --------CSVQSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPKAKSVNTNATKQLLVSSPPAV 914
                    ..::.|:..||..|.:..::...|.:|.:            :..|||:|.:.|.|.|
  Rat   778 YKPPKRPFVKLKDCIELFTTKEKLGAEDPWYCPNCKE------------HQQATKKLDLWSLPPV 830

  Fly   915 LILHLKRFQLGPRCIFRKLTRPVSYP-NLLDIAAFCGSKVKNLPNIDRKQKKLLYALYGVVEHSG 978
            |::|||||... |.:..||...|.:| :.||::.|.         |:.......|.|..|..|.|
  Rat   831 LVVHLKRFSYS-RYMRDKLDTLVDFPISDLDMSEFL---------INPNAGPCRYNLIAVSNHYG 885

  Fly   979 GMYGGHYTAYVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQLKKLEELLAKEKAREQHLKVLDDS 1043
            ||.||||||:.|                       ::||
  Rat   886 GMGGGHYTAFAK-----------------------NKDD-------------------------- 901

  Fly  1044 DDFSNSSSNSSTSDESQTPATPLEEQQTQQAQQPQQPQQLEEAANVRAPPGKWYYVSDSRVQEVS 1108
                                                              |||||..||.|...|
  Rat   902 --------------------------------------------------GKWYYFDDSSVSTAS 916

  Fly  1109 EDTALKAQAYLLFYER 1124
            ||..:...||:|||:|
  Rat   917 EDQIVSKAAYVLFYQR 932

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464	1/5 (20%)
		UBP12	<307..990	CDD:227847	172/751 (23%)
		Peptidase_C19	307..>512	CDD:470612	63/210 (30%)
		Peptidase_C19K	<849..1123	CDD:239132	64/292 (22%)
Usp15	NP_001420766.1	UBP12	12..932	CDD:227847	223/1054 (21%)