Protein Alignment Usp16-45 and Usp16-45

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: XP_311192.6
• Gene: Usp16-45 / 1272450
• VectorBaseID: AGAMI1_001734
• Length: 990
• Species: Anopheles gambiae
• Alignment Length: 1169
• Identity: 465/1169 - (39%)
• Similarity: 613/1169 - (52%)
• Gaps: 222/1169 - (18%)

  Fly     1 MVKKRQADSR--DHDCSTDSGNEDLHHRKGLGSPGQSDGATPTTASCQHIKKAVDAARLRRLLKS 63
            |.|::::|.|  ....||:|.:|.|...|..|.           ..|.||:|::|...:|:.:||
Mosquito     1 MGKRQRSDYRVDGGASSTESNDETLLATKMNGG-----------EMCTHIQKSIDLNTIRKQIKS 54

  Fly    64 T--GLLYECSQCQKLGKTAGSAAGAGASEGAVGPGGNPVTFEFDNTLWLCLKCGSQLCGRARHKH 126
            .  .....||:|  :.:...:..|:..:|    |...|.....|.:||.|||||:|||||.:::|
Mosquito    55 NEEWCRRTCSKC--VDEQQAARGGSYVNE----PLKTPNDINGDTSLWFCLKCGTQLCGRNKNQH 113

  Fly   127 ALEHYQTPHSDSHALAMNTRSFDIWCYECDMKICSNLRKNLLECVELVKKLAQKPPTSTVTPSTP 191
            ||:||.||.||.||||:||.:.|:|||.|.:.:....:..||:.||.||:...|...:.
Mosquito   114 ALQHYATPRSDMHALAINTTTLDVWCYTCSVPVDPYAKPKLLDIVEFVKREIAKVRAAA------ 172

  Fly   192 TISYIEEKLKAALEHLTPIV-----PMTGGSFD-------DSSSRGSLAAAGGGGGVGSSRNRQV 244
              ::.:.:::.|.|.:..:|     ..|..|||       :||.:....:|.|.|
Mosquito   173 --AHTDAQIQNATESVRNLVLDALQSTTNSSFDVPDAAKFNSSDQTYEQSARGKG---------- 225

  Fly   245 AIPMPPPEPSSGLSTSDSLTSVPGMAKRIDQYSATTNGNTGNKRLLTLETPRIENERLPRVRGLT 309
                  ||.:...::|.||  ||...|.:                         .:.|||||||:
Mosquito   226 ------PEAAVPAASSSSL--VPHATKSL-------------------------IDALPRVRGLS 257

  Fly   310 NLGNTCFFNAVMQCLAQTPFLLSVLKELSEPGEEFILPGGTFTIKDKGDIELPMIKGTLSSWGGL 374
            |||||||||||:||||:||:|..:||:.:..||:..:||||..:.|..:|..|.|.|.|.:|..|
Mosquito   258 NLGNTCFFNAVLQCLARTPYLSDILKQSATEGEKVHIPGGTIKLPDGTEILAPPIDGVLDNWRSL 322

  Fly   375 TAALANALEELQAGG-SVFTPRKLFDRLCVKCPQFTGGDQHDAHELLRQLLESVRNEDLKRYQRV 438
            |.||...|.:|||.. ...:|.:|...|..|.|||.||||||:|||||.||||||.:||:|||.:
Mosquito   323 TEALTELLTDLQANAPETLSPNRLLQELTSKWPQFDGGDQHDSHELLRHLLESVRTDDLRRYQSL 387

  Fly   439 ILQNLGYKDQDVNSVSE-EMRQKCKIYGNQAGDRILRPEQVFRGFLVSTLTCQDCHNVSSRHEYF 502
            |||.||.:.:.....:: ..|...|.|..|....:.||||||||.|||||||||||:.||:||||
Mosquito   388 ILQKLGLESRKSRQNTDGTQRALAKYYNEQISQWVFRPEQVFRGSLVSTLTCQDCHHTSSQHEYF 452

  Fly   503 LDMSLPVAVEKPQPPQRRKPSPE---LSLTSSSSSVTPSTGQPTINTKFTDGSVNFTASSPSFFL 564
            ||:||||.|||||||.||:.|||   ..:|..|:....:....|
Mosquito   453 LDISLPVCVEKPQPPVRRRSSPEPDGPGMTGVSAGARGTAAAAT--------------------- 496

  Fly   565 HAHEAASLGPSKSQVKKEKERQRKAKRAAKKRQKSSLNLN---GNDSGNGNELAESVDQDDASLA 626
            ..|.|.|..||    |||:||::||||.| |.||:.:||:   |...|.|...|          |
Mosquito   497 GGHTALSKAPS----KKEREREKKAKRIA-KHQKNRINLSSVGGVVGGIGTTAA----------A 546

  Fly   627 SLGAGDGQANDGLEQTNGQTEDST-----------TSSVTTSEHSDADVEDNLVEDTAAPSTNNV 680
            ...|..|..::.:......|||.:           .||..:||.||||||||.|.|.|.....:.
Mosquito   547 EQPASAGDESEAMANMVPLTEDHSFQSDCAKGNDDGSSDESSEPSDADVEDNDVTDDALSKCGSA 611

  Fly   681 PSSTASLTAPSKTYMDSNGN---AQPPGEKRDDTPEHMDKDSLEEDENDSGIATSPAPTATNSST 742
            |:            :|.|||   :.|  ||.||.||:.:|:|
Mosquito   612 PA------------VDQNGNQLRSMP--EKSDDAPENSNKES----------------------- 639

  Fly   743 STSATGNNNSVAGSGLSGSSGALEDPLAPASLVTAGLSEKGASVIRQVSVGAEQGASNGTEDADG 807
                 ..:|.|...|:|                    :::.|.::||:|     |.:.|:.:.|.
Mosquito   640 -----DGSNIVCEVGIS--------------------AQRAAHMVRQLS-----GGNGGSSETDE 674

  Fly   808 EAKAIEQPEKTPSQAQA-MAQAQARTKRVRTQSYSDWSTTIAPRYQCEDGECSVQSCLNNFTAVE 871
            ||....|..:....... ....:.:..|.||.|::|||.||||||||||||.|||||.|||||||
Mosquito   675 EASRQRQGARAGGAGDVDTCTGEPKRGRQRTFSHADWSNTIAPRYQCEDGEYSVQSCFNNFTAVE 739

  Fly   872 LMTGQNKVGCDSCTQRINGSDPKAKSVNTNATKQLLVSSPPAVLILHLKRFQLGPRCIFRKLTRP 936
            ||||.|||.|::||:||||..  ..|||||||||.|:|.|||||||||||||:|.|.:|:||.:.
Mosquito   740 LMTGNNKVCCEACTERINGKG--GPSVNTNATKQFLISQPPAVLILHLKRFQVGLRSVFKKLNKL 802

  Fly   937 VSYPNLLDIAAFCGSKVKNLPNIDRKQKKLLYALYGVVEHSGGMYGGHYTAYVKVRPKVAPGDKR 1001
            ||:|.:||||.|||||||...:|...|||:||||||:|||||.|:||||.|||||||...|||.|
Mosquito   803 VSFPFVLDIAPFCGSKVKRASHIRPGQKKILYALYGLVEHSGSMHGGHYVAYVKVRPTFGPGDPR 867

  Fly  1002 WKFLPHGSKAELDQDDDQLKKLEELLAKEKAREQHLKVLDDSDDFSNSSSNSSTSDESQTPATPL 1066
            |||:|.|:|.|||      :|.|:.:|||:|....|.|.|..|.||:|.:.|...:..:..:.|.
Mosquito   868 WKFIPQGTKDELD------RKSEQEMAKEQAMRMGLHVRDSDDSFSSSHTPSDNDECGRKRSQPR 926

  Fly  1067 EEQQTQQAQ----QPQQPQQLEEAANVRAPPGKWYYVSDSRVQEVSEDTALKAQAYLLFYERIY 1126
            :.|...:.:    ...:||....|..|..||||||.||||.|:||:|::.||.||||||||||:
Mosquito   927 DRQPQDELEGAVGYAHKPQARPAAEEVETPPGKWYCVSDSYVREVTEESVLKVQAYLLFYERIF 990

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464	32/50 (64%)
		UBP12	<307..990	CDD:227847	310/705 (44%)
		Peptidase_C19	307..>512	CDD:470612	112/206 (54%)
		Peptidase_C19K	<849..1123	CDD:239132	160/277 (58%)
Usp16-45	XP_311192.6	None