Protein Alignment Usp16-45 and USP17L10

DIOPT Version :10

• Sequence 1: NP_572220.1
• Gene: Usp16-45 / 31458
• FlyBaseID: FBgn0029763
• Length: 1126
• Species: Drosophila melanogaster
• Sequence 2: NP_001243781.1
• Gene: USP17L10 / 100287144
• HGNCID: 44438
• Length: 530
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 61/270 - (22%)
• Similarity: 98/270 - (36%)
• Gaps: 75/270 - (27%)

  Fly   859 SVQSCLNNFTAVELMTGQNKVGCDSCTQRINGSDPKAKSVNTNATKQLLVSSPPAVLILHLKRFQ 923
            |||..|......|.:.|:|...|..|.||            ..|:|.|.:.:...||||.||||
Human   232 SVQQALEQLVKPEELNGENAYHCGVCLQR------------APASKTLTLHNSAKVLILVLKRF- 283

  Fly   924 LGPRCIFRKLTRPVSYPNLLDIAAFCGSKVKNLPNIDRKQKKLLYALYGVVEHSG-GMYGGHYTA 987
              |.....|:.:.|.||..||:..:..         .:....|:|.||.|:.|:| ..:.|||::
Human   284 --PDVTGNKIAKNVQYPECLDMQPYMS---------QQNTGPLVYVLYAVLVHAGWSCHNGHYSS 337

  Fly   988 YVKVRPKVAPGDKRWKFLPHGSKAELDQDDDQLKKLEELLAKE--------------------KA 1032
            |||.:              .|...::|..:.....:..:|:::                    :.
Human   338 YVKAQ--------------EGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRG 388

  Fly  1033 REQHLKVLDDSDDFSNSSSNSSTSDESQTPATPLEEQQTQQAQQP---------QQPQQLEEAAN 1088
            ||.....::|:|  ..::......|.....|..|:|...::|.|.         |:..:.:...|
Human   389 REPRALGVEDTD--RRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFN 451

  Fly  1089 VR-----APP 1093
            ||     .||
Human   452 VRRVEGTVPP 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp16-45	NP_572220.1	zf-UBP	108..159	CDD:460464
		UBP12	<307..990	CDD:227847	40/131 (31%)
		Peptidase_C19	307..>512	CDD:470612
		Peptidase_C19K	<849..1123	CDD:239132	61/270 (23%)
USP17L10	NP_001243781.1	Peptidase_C19E	79..373	CDD:239126	45/178 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	382..410		4/29 (14%)
		HABP4_PAI-RBP1	<417..453	CDD:461421	7/35 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	477..530