DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NAAT1 and zgc:158427

DIOPT Version :9

Sequence 1:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	XP_017207457.1	Gene:	zgc:158427 / 790932	ZFINID:	ZDB-GENE-061215-110	Length:	579	Species:	Danio rerio

Alignment Length:	619	Identity:	222/619 - (35%)
Similarity:	324/619 - (52%)	Gaps:	59/619 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 STEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGK 89
            ||.|...|    ||..||...|||::.....||||||||||:..|.||||.|||||::.:...|.
Zfish     2 STIKEKIE----ERGFWGKKTEFLLAVAGNVVGLGNVWRFPYLCYRNGGGVFLIPYLVFVVTCGV 62

  Fly    90 PMYYLEMIMGQFTSQGTVKIW-SVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSEL 153
            |::.||..|||||.:|.:..| .:.|...|:||......:....|::.:||..|:||..||.|:|
Zfish    63 PLFLLETAMGQFTHEGGITCWHRLCPLAQGIGYAGQLTVLYSCMYFTIILAWALFYLISSFSSQL 127

  Fly   154 PWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVI 216
            ||:.|.:.|.  ||||........|..|.:.:.:.||                 ::|.:...|
Zfish   128 PWASCDNIWNTDNCVNLAAGNLTFNRTTQMLINSTSA-----------------ATEFWERRV-- 173

  Fly   217 KEKLDISDG---VGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAV 278
               |.:|.|   :|..:|::.|.|...|::.:..|.:||||:||..||.|.||||:|.|||||.:
Zfish   174 ---LSLSGGIEDIGKINWEILLCLIAMWIICYFCIWKGVKSTGKVVYFTATFPYVMLIVLLIRGL 235

  Fly   279 TLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVT 343
            ||.||..||:|:|.|:...|.:|.||.||..|.|||.:|..|.:|...|||::::..|||...:.
Zfish   236 TLPGALQGIVFYLYPEPARLADPQVWMEAGTQIFFSYSVIGGVLISLGSYNQYNNNCYRDCFWLC 300

  Fly   344 TLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFF 408
            .|::.||.:.|..:|::||.:|| :|...|.:|..||.|||||:||.|:: ....|||::|.||.
Zfish   301 LLNSGTSFVAGFAVFSVLGFMAH-VQGVPIEEVAESGPGLAFIAYPQAVA-MMPFPQLWAVCFFI 363

  Fly   409 MLFVLGIGSIVALQSTIVTIICDQF------KGWKYWKVALTTSVCGFLMGLVYVTPGGQWILTL 467
            |:.:||:.:.......::|.:.|.|      .|.:...|.|....| |...|:.||.||.::..|
Zfish   364 MIILLGLDTQFVSVECVITSVMDLFPEVLRRAGRRELLVLLLCLTC-FFGQLIMVTEGGMYVFQL 427

  Fly   468 VDFY--GGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFI 530
            .|.|  .|..::| |::||...|.|::|.:...|.||.|...|.:.::.:||.:.||::.:..|:
Zfish   428 FDNYACNGACLLF-LSVFESLAIGWIFGAEKMFDIIEDMTESRPNYWFMLCWKYLTPLVSLTSFV 491

  Fly   531 YSMVTIEPIKYSELY-FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKPSDR 594
            ||||...|:.::..| :|:.|.:.||||........|.|.|..:.         :.|.|||  .|
Zfish   492 YSMVRYTPLTFNRWYIYPDWAYVLGWLLALSSILLVPAWALGQMC---------AGKGSLK--QR 545

  Fly   595 WGP-ANPEIRREWVIFKNQKAAQRATQKDTSKLG 627
            |.. ::||.... :.|| |...|.|..:|..|.|
Zfish   546 WRHLSSPETNFP-LSFK-QVQKQTAEMEDLLKSG 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	186/506 (37%)
zgc:158427	XP_017207457.1	SLC6sbd-TauT-like	11..552	CDD:271387	207/577 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820