Protein Alignment NAAT1 and SLC6A13

DIOPT Version :10

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_057699.2
• Gene: SLC6A13 / 6540
• HGNCID: 11046
• Length: 602
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 221/604 - (36%)
• Similarity: 321/604 - (53%)
• Gaps: 46/604 - (7%)

  Fly    13 SNGSGNGATNAA--STEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGA 75
            |..:.||.|...  ..||.: |..|.||.:|.|.:||::|.....:|||||||||:..|:|||||
Human     6 SGTTSNGETKPVYPVMEKKE-EDGTLERGHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGA 69

  Fly    76 FLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIW-SVVPGFVGVGYGQAFGTICIISYYSSLLA 139
            |.|||::.||..|.|::.||..:||:||||.|..| .:.|.|.|:||......|.:..||..:||
Human    70 FFIPYLVFLFTCGIPVFLLETALGQYTSQGGVTAWRKICPIFEGIGYASQMIVILLNVYYIIVLA 134

  Fly   140 LTLYYLFVSFQSELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEK 202
            ..|:|||.||..:|||..|..||.  :|:..:.        |..||...|....|.::...|
Human   135 WALFYLFSSFTIDLPWGGCYHEWNTEHCMEFQK--------TNGSLNGTSENATSPVIEFWE--- 188

  Fly   203 LQSSSELYFLNVVIKEKLDISDGV---GDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLAL 264
                          :..|.||||:   |...|:|.|.|.:|||:.:..|.:||||:||..||.|.
Human   189 --------------RRVLKISDGIQHLGALRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTAT 239

  Fly   265 FPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYN 329
            |||::|.|||||.|||.||..||.|:|.|....|.:|.||.:|..|.|||.|:..|.:....|||
Human   240 FPYLMLVVLLIRGVTLPGAAQGIQFYLYPNLTRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYN 304

  Fly   330 RFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISK 394
            ::.:..|||.:.:..|::.||.:.|..||:|||.::....:. |.:|..||.|||||:||.|:..
Human   305 KYHNNCYRDCIALCFLNSGTSFVAGFAIFSILGFMSQEQGVP-ISEVAESGPGLAFIAYPRAVVM 368

  Fly   395 FQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQF-----KGWKYWKVALTTSVCGFLMGL 454
            ....| |::..||||:.:||:.|......::||.:.|.:     |..:...:.|..||..||:||
Human   369 LPFSP-LWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPHVFRKKNRREVLILGVSVVSFLVGL 432

  Fly   455 VYVTPGGQWILTLVDFY--GGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCW 517
            :.:|.||.::..|.|:|  .|..::|: ||||...:.||||.:.|.|:||.|...|.....:.||
Human   433 IMLTEGGMYVFQLFDYYAASGMCLLFV-AIFESLCVAWVYGAKRFYDNIEDMIGYRPWPLIKYCW 496

  Fly   518 SFFTPVMMIIIFIYSMVTIEPIKYSELY-FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTY 581
            .|.||.:....|::|::...|:.|::.| :|...:..||||........|.|.|:.:.. .:|.:
Human   497 LFLTPAVCTATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSLYRLGT-LKGPF 560

  Fly   582 WKSLKASLKPSDRWGPANP 600
            .:.::..:.|::.....||
Human   561 RERIRQLMCPAEDLPQRNP 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	195/505 (39%)
SLC6A13	NP_057699.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		4/15 (27%)
		SLC6sbd_GAT2	32..575	CDD:271396	210/571 (37%)