Protein Alignment NAAT1 and SLC6A12

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001116319.1
• Gene: SLC6A12 / 6539
• HGNCID: 11045
• Length: 614
• Species: Homo sapiens
• Alignment Length: 582
• Identity: 210/582 - (36%)
• Similarity: 313/582 - (53%)
• Gaps: 46/582 - (7%)

  Fly    27 EKTDA--EKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGK 89
            ||.|.  |....:|..|.|.:||::|.....:|||||||||:..|:||||||.|||.|..|:.|.
Human    23 EKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGI 87

  Fly    90 PMYYLEMIMGQFTSQGTVKIW-SVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSEL 153
            |:::||:.:||:||||:|..| .:.|.|.|:|.........:..||..:||..|:|||.||.|||
Human    88 PVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSEL 152

  Fly   154 PWSYCRDEWTNCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVI-- 216
            ||:.|.:.|..       |:..:.|      |.|.   :|.|...|.          |.:.|:
Human   153 PWTTCNNFWNT-------EHCTDFL------NHSG---AGTVTPFEN----------FTSPVMEF 191

  Fly   217 --KEKLDISDGV---GDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIR 276
              :..|.|:.|:   |...|:|.|.|.:|||:.:..|.:||||:||..||.|.|||::|.:||||
Human   192 WERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIR 256

  Fly   277 AVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMI 341
            .|||.||..||:::|:|....|.:|.||.:|..|.|||.|:..|.:....|||::.:..|:|.:.
Human   257 GVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIA 321

  Fly   342 VTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLF 406
            :..|::.||.:.|..:|:|||.::....:. |.:|..||.|||||::|.|:: ...:.||:|.||
Human   322 LCFLNSATSFVAGFVVFSILGFMSQEQGVP-ISEVAESGPGLAFIAFPKAVT-MMPLSQLWSCLF 384

  Fly   407 FFMLFVLGIGSIVALQSTIVTIICDQF-----KGWKYWKVALTTSVCGFLMGLVYVTPGGQWILT 466
            |.||..||:.|.......:||...|.|     |..:...:.||.:|..:|:||..||.||.:|..
Human   385 FIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQ 449

  Fly   467 LVDFYGGTYV-VFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFI 530
            |.|:|..:.: :..|::||:..|.||||...|.|:||.|...|.....::.|.|.||.:.:..|:
Human   450 LFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFL 514

  Fly   531 YSMVTIEPIKYSELY-FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKP 591
            :|:....|:||:.:| :|......||.|........||:.:..:.: .:|.:.|.|:..:.|
Human   515 FSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLK-TRGPFRKRLRQLITP 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	190/506 (38%)
SLC6A12	NP_001116319.1	SLC6sbd_BGT1	35..575	CDD:212080	205/568 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	576..614		210/582 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820