Protein Alignment NAAT1 and SLC6A9

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_964012.2
• Gene: SLC6A9 / 6536
• HGNCID: 11056
• Length: 706
• Species: Homo sapiens
• Alignment Length: 600
• Identity: 224/600 - (37%)
• Similarity: 349/600 - (58%)
• Gaps: 35/600 - (5%)

  Fly    18 NGATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYII 82
            |||..:.:|::..    ..:|.||||.:||:::.:..:||||||||||:..|.||||||:.||.|
Human    84 NGAVPSEATKRDQ----NLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAFMFPYFI 144

  Fly    83 VLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFV 147
            :|...|.|::::|:..|||.|||.:.:|.:.|.|.|||||....:..|..||:.::.:..||.|.
Human   145 MLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIAFYYFFS 209

  Fly   148 SFQSELPWSYCRDEWT--NCVNSRPQEYVDNLLTGVSLANES-----ARNLSGIVANDETEKLQS 205
            |....|||:||.:.|.  :|.         .:|...:|.|.|     ..|||.:: |...::...
Human   210 SMTHVLPWAYCNNPWNTHDCA---------GVLDASNLTNGSRPAALPSNLSHLL-NHSLQRTSP 264

  Fly   206 SSELYFLNVVIKEKLDISDGVGD-PDWKLTL--ALFVAWVVIFLVIMRGVKSSGKAAYFLALFPY 267
            |.|.:.|.|     |.:||.:|: .:.:|.|  .|.|:|:|:||.::||||||||..||.|.|||
Human   265 SEEYWRLYV-----LKLSDDIGNFGEVRLPLLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPY 324

  Fly   268 VVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFD 332
            |||.:|.:|.||||||.|||:::|.|||.::|...||.:|..|.|:||....|.:|..||||:|.
Human   325 VVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFH 389

  Fly   333 HGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQA 397
            :..|||::|::..:..||:..|..||:|||.:|::|.:: :..|...|.||||::||:|::....
Human   390 NNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVD-VSRVADHGPGLAFVAYPEALTLLPI 453

  Fly   398 VPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQF-KGW---KYWKVALTTSVCGFLMGLVYVT 458
            .| |:|:||||||.:||:|:...|..|:||.|.|:. ..|   |...|.|..:|.|||:|:...:
Human   454 SP-LWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGNEWILQKKTYVTLGVAVAGFLLGIPLTS 517

  Fly   459 PGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPV 523
            ..|.:.|.|:|.|..::.:.:::......|:::||.:|:..||:.|......|::::||.|.:|.
Human   518 QAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPA 582

  Fly   524 MMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKAS 588
            ::..|.:::::..:||.|:...:|..|...|:|:........||:.::.:.|....|..:.||.:
Human   583 IIFFILVFTVIQYQPITYNHYQYPGWAVAIGFLMALSSVLCIPLYAMFRLCRTDGDTLLQRLKNA 647

  Fly   589 LKPSDRWGPANPEIR 603
            .|||..||||..|.|
Human   648 TKPSRDWGPALLEHR 662

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	197/506 (39%)
SLC6A9	NP_964012.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		SLC6sbd_GlyT1	84..667	CDD:212067	223/599 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820