Protein Alignment NAAT1 and SLC6A2

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001165975.1
• Gene: SLC6A2 / 6530
• HGNCID: 11048
• Length: 628
• Species: Homo sapiens
• Alignment Length: 643
• Identity: 228/643 - (35%)
• Similarity: 344/643 - (53%)
• Gaps: 60/643 - (9%)

  Fly     6 VQPSNGSSNGSGNGATNAASTEKT---------------------DAEKPTAERTNWGNGLEFLM 49
            |||.|   ||:..|........||                     ||:    .|..||..::||:
Human    10 VQPEN---NGADTGPEQPLRARKTAELLVVKERNGVQCLLAPRDGDAQ----PRETWGKKIDFLL 67

  Fly    50 SCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVP 114
            |.:..:|.|.||||||:..|:||||||||||.:.|.:.|.|::|:|:.:||:..:|...:|.:.|
Human    68 SVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVWKICP 132

  Fly   115 GFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWT--NCVNSRPQEYVDNL 177
            .|.||||......:.:..||:.::|.:|||||.||...|||:.|...|.  ||.:.:       |
Human   133 FFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPK-------L 190

  Fly   178 LTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVV-IKEKLDISDGVGDPDWKLTLALFVAW 241
            |.|..|.|.:..:         ..|...::|.|...|: :.|...|.| :|.|.|:|.|.|.|..
Human   191 LNGSVLGNHTKYS---------KYKFTPAAEFYERGVLHLHESSGIHD-IGLPQWQLLLCLMVVV 245

  Fly   242 VVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKE 306
            :|::..:.:|||:|||..:..|..||.||||||:..|||.||.:||..:|...:..|...|||.:
Human   246 IVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWID 310

  Fly   307 AVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIE 371
            |..|.||||..|.|.:|.|||||:||:..||||::.::::.:||.:.|..||:|||.:||..::
Human   311 AATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKV- 374

  Fly   372 NIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGW 436
            ||.||...|.||.||.||:|||.... ...::|:||.||..||:.|.:.....::|.:.|.|:..
Human   375 NIEDVATEGAGLVFILYPEAISTLSG-STFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVL 438

  Fly   437 KYWKVALTTSV--CGFLMGLVYVTPGGQWILTLVD-FYGGTYVVFILAIFELAGIVWVYGLQNFC 498
            |..:...|..|  ..||:.|..:|.||.::|||:| |..||.::|.: :.|..|:.|.||:..|.
Human   439 KRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAV-LMEAIGVSWFYGVDRFS 502

  Fly   499 DDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAA 563
            :||:.|...|..||||:||.|.:|..::.:.:.|::..:|:.|.:..||..||..||.:......
Human   503 NDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWGIALSSMV 567

  Fly   564 QFPLWGLW-YISRHPQGTYWKSLKASLKP-SDRWGPANPEIRREWVIFKNQKAAQRAT 619
            ..|::.:: ::|  .||:.|:.|...:.| ::....|..:||:  ...|.::..:|||
Human   568 LVPIYVIYKFLS--TQGSLWERLAYGITPENEHHLVAQRDIRQ--FQMKTRQGRRRAT 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	193/498 (39%)
SLC6A2	NP_001165975.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		7/15 (47%)
		SLC6sbd_NET	56..612	CDD:212081	213/579 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820