DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NAAT1 and si:ch211-132b12.2

DIOPT Version :9

Sequence 1:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001038688.1	Gene:	si:ch211-132b12.2 / 571877	ZFINID:	ZDB-GENE-050420-178	Length:	582	Species:	Danio rerio

Alignment Length:	574	Identity:	203/574 - (35%)
Similarity:	312/574 - (54%)	Gaps:	54/574 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 ERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQF 101
            ||.|||:..||:::...:.:|||||||||:..|:|||||||:||::.:...|.|::.||..|||:
Zfish    10 ERGNWGSKTEFILAVAGIVIGLGNVWRFPYLCYKNGGGAFLVPYLVFVVTCGVPLFLLETAMGQY 74

  Fly   102 TSQGTVKIW-SVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWTN- 164
            |.:|.:..| .:.|...|:||......:....||..:||..|:||..||.|:|||:.|.:.|..
Zfish    75 TQEGGITCWHRLCPLAEGIGYAGQLIVLYSCMYYIIILAWALFYLAFSFSSQLPWASCDNIWNTD 139

  Fly   165 -CVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISDG--- 225
             |||               || |:..|||..:..:.|   .|.:|.:...|     |.:|.|
Zfish   140 ACVN---------------LA-ENKLNLSTPMLLNST---SSVTEFWQHRV-----LALSGGIEK 180

  Fly   226 VGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFF 290
            ||..:|::.|.|.|.|::.:..:.:||||:||..||.|.||||:|.|||||.:||.||..|::|:
Zfish   181 VGKINWEILLCLIVMWIICYFCVWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFY 245

  Fly   291 LEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGI 355
            |.|:...|.:|.||.||..|.|||.|:|:..:.:..|||::::..||.::.:..|::.||::.|.
Zfish   246 LYPEPARLADPQVWMEAGAQIFFSYALGTASLTVLGSYNKYNYNCYRSSLWLCLLNSSTSVIAGF 310

  Fly   356 TIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVA 420
            .:|::||.:|....:. |.:|..||.|||||:||.|:: ....|||::..||.|:.:||:.:...
Zfish   311 AVFSVLGFMAQKQGLP-IEEVAESGPGLAFIAYPQAVA-MMPFPQLWAACFFIMIILLGLDTQFV 373

  Fly   421 LQSTIVTIICDQF------KGWKYWKVALTTSVCGFLMGLVYVTPGGQWILTLVDFY--GGTYVV 477
            .....:|.:.|.|      .|.:...:.|....| |...||.||.||.::..|.|:|  .|..::
Zfish   374 AMEVFMTSVIDLFPTVLRKAGRREIFLLLFCLFC-FFGQLVMVTEGGMYVFQLFDYYACSGACLL 437

  Fly   478 FILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYS 542
            | |.:||...:.||:|.:.....||.|.|.|.:.::.:||.:.||::.:..|:.|:|..:|:.::
Zfish   438 F-LCVFESLAMGWVFGAEKMFGIIEDMTNSRPNYWFMLCWKYLTPIVSLASFVCSLVKYKPLTFN 501

  Fly   543 ELY-FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKPSDRW 595
            ..| :|:.|.:.||||........|.|.|        |..:.. |.|:|  .||
Zfish   502 RWYVYPDWAYVLGWLLALSSILLVPGWAL--------GRMFAG-KGSIK--QRW 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	182/506 (36%)
si:ch211-132b12.2	NP_001038688.1	SLC6sbd-TauT-like	11..550	CDD:271387	202/573 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820