DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NAAT1 and si:ch211-132b12.6

DIOPT Version :9

Sequence 1:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001038523.1	Gene:	si:ch211-132b12.6 / 564583	ZFINID:	ZDB-GENE-050420-179	Length:	577	Species:	Danio rerio

Alignment Length:	583	Identity:	215/583 - (36%)
Similarity:	312/583 - (53%)	Gaps:	55/583 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 ERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQF 101
            ||..||...|||::.....||||||||||:..|.||||.|||||::.:...|.|::.||..||||
Zfish    10 ERGFWGKKAEFLLAVAGNVVGLGNVWRFPYLCYRNGGGVFLIPYLVFVVTCGLPLFLLETAMGQF 74

  Fly   102 TSQGTVKIW-SVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWT-- 163
            |.:|.:..| .:.|...||||......:....||:.:||..|:||..||.|:|||..|.:.|.
Zfish    75 THEGGITCWHRLCPLAQGVGYAGQLTVLYSCMYYTIILAWALFYLVSSFSSQLPWVSCNNIWNTD 139

  Fly   164 NCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISDG--- 225
            ||||........|..|   |||.::                :::|.:...|     |.:|.|
Zfish   140 NCVNLAAGNLTFNRTT---LANSTS----------------AATEFWERRV-----LSLSGGIED 180

  Fly   226 VGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFF 290
            :|..:|::.|.|...|::.:..|.:||||:||..||.|.||||:|.|||||.:||.||..|::|:
Zfish   181 IGKINWEILLCLIAMWIICYFCIWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFY 245

  Fly   291 LEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGI 355
            |.|:...|.:|.||.||..|.|||.:|.||.:|...|||::.:..|||:..:..|::.||.:.|.
Zfish   246 LYPEPARLADPQVWMEAGTQVFFSYSVCSGILISLGSYNQYSNNCYRDSFWLCLLNSGTSFVAGF 310

  Fly   356 TIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVA 420
            .:|::||.:|| :|...:.:|..||.|||||:||.|:: ....|||::|.||.|:.:||:.|...
Zfish   311 AVFSVLGFMAH-VQGVPVEEVAESGPGLAFIAYPQAMA-MMPFPQLWAVCFFIMIILLGLDSQFV 373

  Fly   421 LQSTIVTIICDQF------KGWKYWKVALTTSVCGFLMGLVYVTPGGQWILTLVDFY--GGTYVV 477
            ....::|.:.|.|      .|.:...|.|....| |...|:.||.||.::..|.|.|  .|..::
Zfish   374 GIECVITSVMDLFPEVLRRAGRRELFVLLLCLTC-FFGQLIMVTEGGMYVFQLFDNYACNGACLL 437

  Fly   478 FILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYS 542
            | |::||...|.|::|.:...|.||.|...|.:.::.:||.:.||::.::.|:||||...|:.::
Zfish   438 F-LSVFESLAIGWLFGAEKMFDIIEDMTESRPNYWFMLCWKYLTPLVSLMSFVYSMVRYTPLTFN 501

  Fly   543 ELY-FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKPSDRWGP-ANPEIR 603
            ..| :|:.|...||||........|.|.|        |..|.. |.:||  .|||. .:||.:
Zfish   502 RWYVYPDWAYALGWLLALSSILLVPGWAL--------GQMWAG-KGTLK--QRWGHLCSPETK 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	189/506 (37%)
si:ch211-132b12.6	NP_001038523.1	SLC6sbd-TauT-like	11..550	CDD:271387	212/577 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920