DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NAAT1 and si:ch211-225b11.1

DIOPT Version :9

Sequence 1:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001103931.1	Gene:	si:ch211-225b11.1 / 561694	ZFINID:	ZDB-GENE-060531-39	Length:	609	Species:	Danio rerio

Alignment Length:	590	Identity:	212/590 - (35%)
Similarity:	320/590 - (54%)	Gaps:	58/590 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVL 84
            ||..|..|:..||    .|..||..|||:::.|..:||||||||||:..|.:|||||||||:|:|
Zfish    40 ATRLAKVEQQAAE----PRETWGRRLEFVLATIGYAVGLGNVWRFPYLCYRSGGGAFLIPYMIML 100

  Fly    85 FLIGKPMYYLEMIMGQFTSQGTV-KIWSVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVS 148
            ||.|.|:.::|..:||:|..|.| .:..:.|.|.|||......:..:.:||:.|:...||||..|
Zfish   101 FLCGIPLLFMEFTVGQYTRLGPVHALAQICPLFKGVGLATVVISYVLCTYYNVLMTWALYYLLHS 165

  Fly   149 FQSELPWSYCRDEWTNCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLN 213
            |...|||..|.:.|....|..                      :|...|  ...|||:|:.:|.:
Zfish   166 FSPSLPWQSCNNTWNTVANCS----------------------TGFPGN--ATHLQSASQQFFDH 206

  Fly   214 VVIKEKLDISDGV---GDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLI 275
            .|    |:::.|:   |...|:|...|.:||.:::..|.:||||:||..||.|.|||.:||.||:
Zfish   207 KV----LEMTSGIERAGGVRWELFGLLVLAWGIVYFCIFKGVKSTGKVVYFTATFPYFILFALLV 267

  Fly   276 RAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAM 340
            ..|.|.||::||||||.|.|.:||...||..|..|.|.|:.:..|.:|..||||::::.|.||..
Zfish   268 NNVQLPGAKNGILFFLMPNWSKLLEVQVWVNAAAQIFNSIGISFGSMISMASYNKYNNNILRDTF 332

  Fly   341 IVTTLDTLTSLLGGITIFAILGNLA--HNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFS 403
            ||:..::.||::.|..||:.:|.:|  |||.::   |:...|.||.|:.||:..|. ..|.||::
Zfish   333 IVSLANSATSIVAGFVIFSAIGYMAHIHNLPVD---DIATDGPGLVFVVYPEVFST-MPVSQLWA 393

  Fly   404 VLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKV-----ALTTSVC--GFLMGLVYVTPGG 461
            .|||.||..||:.|..|:....||.|.|.| |.|..||     .:..:||  |||:|:.::|.||
Zfish   394 PLFFIMLLCLGLDSQFAMVEVAVTFIMDGF-GRKALKVFKRKELIVLAVCSFGFLLGIPHITRGG 457

  Fly   462 QWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMI 526
            .::..|:|.|.....:..||.||:..:..::|::.....:|.|..::.:|::|:||.:.:|::::
Zfish   458 IYVFQLMDHYTAVVSLMFLAFFEVLAVTLIFGVKRLSVMVENMLGKKPNLFFRICWQYLSPMLVL 522

  Fly   527 IIFIYSMVTIEPIKYSELY-FPEAANIAGWLLFAIGAAQFPLWG---LWYISRHPQGTYWKSLKA 587
            .|.|.|:|...|.:|.:.| :|..|.:.||.:..:.....||..   ||    ..:|:..:.||.
Zfish   523 GILISSIVQYTPARYGKSYTYPLWAELLGWFISLVSIIWIPLGALHELW----TTEGSLLQRLKK 583

  Fly   588 SLKPS 592
            |:.|:
Zfish   584 SITPT 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	187/505 (37%)
si:ch211-225b11.1	NP_001103931.1	SLC5-6-like_sbd	54..587	CDD:294310	205/569 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920