Protein Alignment NAAT1 and slc6a22.2

DIOPT Version :10

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_068077846.1
• Gene: slc6a22.2 / 561024
• ZFINID: ZDB-GENE-030616-628
• Length: 619
• Species: Danio rerio
• Alignment Length: 602
• Identity: 211/602 - (35%)
• Similarity: 313/602 - (51%)
• Gaps: 75/602 - (12%)

  Fly    18 NGATNAASTEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYII 82
            |||...|      ..||.| |..|.|.||||::.....:|||||||||:..|:||||||.:||::
Zfish    26 NGALVKA------RPKPPA-REQWANKLEFLLAVAGHIIGLGNVWRFPYLCYKNGGGAFFVPYVL 83

  Fly    83 VLFLIGKPMYYLEMIMGQFTSQGTVKIW-SVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLF 146
            .||..|.|:::||..:|||||||.:..| .:.|.|.|:|:|.....:....||..:||....|||
Zfish    84 FLFTCGIPLFFLETSLGQFTSQGGITCWRKICPLFEGLGFGSQVVVLYTGVYYIIILAWAFLYLF 148

  Fly   147 VSFQSELPWSYCRDEWT--NCV---NSRPQEYVDNLLTG--VSLANESARNLSGIVANDETEKLQ 204
            .||.|||||:.|.:.|.  :|:   .|...||..|..|.  :.........|||.:
Zfish   149 SSFTSELPWASCNNYWNTPSCMEFSESNITEYSPNKTTSPVIEFWERRILGLSGGI--------- 204

  Fly   205 SSSELYFLNVVIKEKLDISDGVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVV 269
                               :.:|:..|.|.|.|.:||::.:..:.:||||:||..||.|.|||::
Zfish   205 -------------------EQIGNVRWDLALCLLLAWIICYFCVWKGVKSTGKVVYFTATFPYLM 250

  Fly   270 LFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHG 334
            |.|||:|.:||.||.:||.|:|.|....|.:|.||.:|..|.|:|..|.:|.:....|||::|:.
Zfish   251 LIVLLVRGLTLPGAINGITFYLYPDPSRLKDPQVWMDAGSQIFYSYGVCTGVLTALGSYNKYDNN 315

  Fly   335 IYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVP 399
            .|||.:.:..|::|||.:.|..||::||.:|....:: |..|..||.|||||:||.|:: ...:|
Zfish   316 CYRDCVYLCLLNSLTSFVAGFAIFSVLGFMADEQGVD-ISLVAESGPGLAFIAYPRAVA-LMPLP 378

  Fly   400 QLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGWKYWKVA-----LTTSVC--GFLMGLVYV 457
            ||:::.||.|:..||:.|....|..:||.|.|.:.  .:::|.     |...:|  .|.:||:.|
Zfish   379 QLWAIFFFIMIIFLGLDSEFVYQEALVTSISDMYP--SFFQVGHRRKFLLLFICSASFFVGLLMV 441

  Fly   458 TPGGQWILTLVDFY---GGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSF 519
            |.||.::..|.|:|   |.|.:.|  ||.:...:.||||.....|.:|.|...|...:.:.||.:
Zfish   442 TEGGLYVFQLFDYYACSGMTLLTF--AILQSICVGWVYGADRHYDCVEDMIGYRPWPFMKCCWKY 504

  Fly   520 FTPVMMIIIFIYSMVTIEPIKYSELY-FPEAANIAGWLLFAIG-------AAQFPLWGLWYISRH 576
            .||.:....||:|:|...|:|::..| :|       |..:|||       ....|||.::.:...
Zfish   505 LTPAICTGTFIFSLVQYTPLKFNNEYEYP-------WWGYAIGGFFTLSSTLLVPLWMIYLVGTT 562

  Fly   577 PQGTYWKSLKASLKPSD 593
            | |:..:.::|...|::
Zfish   563 P-GSMRQRVRALCTPAE 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	186/510 (36%)
slc6a22.2	XP_068077846.1	SLC6sbd-TauT-like	39..576	CDD:271387	203/578 (35%)