Protein Alignment NAAT1 and SLC6A20

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001372612.1
• Gene: SLC6A20 / 54716
• HGNCID: 30927
• Length: 603
• Species: Homo sapiens
• Alignment Length: 647
• Identity: 202/647 - (31%)
• Similarity: 308/647 - (47%)
• Gaps: 134/647 - (20%)

  Fly    38 RTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFT 102
            |..|.|.|:|:.:|||.:||||||||||:.....|||:||:||||:|.:.|.|:.|||:.:||..
Human     5 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRM 69

  Fly   103 SQGTVKIW-SVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWTNCV 166
            .||::..| ::.|...|||......:..:..||:.:.|...:|||.|||..||||.|.
Human    70 RQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCP------- 127

  Fly   167 NSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISDGV---GD 228
                       |.|         |.:|.  ::|.||..|:...::     ::.|:||..:   |.
Human   128 -----------LNG---------NHTGY--DEECEKASSTQYFWY-----RKTLNISPSLQENGG 165

  Fly   229 PDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEP 293
            ..|:..|.|.:||:|::|.|:||.:|:||..||.|..||.||.:.|||.:||.||.:|:::...|
Human   166 VQWEPALCLLLAWLVVYLCILRGTESTGKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTP 230

  Fly   294 -----------QWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDT 347
                       |..:|.||..|..|..|.||||.:|.|.:|.|||||...:...:.|:||:.:::
Human   231 KGSSALSLLAFQIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINS 295

  Fly   348 LTSLLGGITIFAILG--------------------------------NLAH-------------- 366
            .||:...|..|:|.|                                ||..
Human   296 FTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTFDLEDGFLTASNLEQVKGYLASAYPSKYS 360

  Fly   367 -------NLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQST 424
                   |..:|:..|....|||||||.|.:||...: |.||:|||:||||.:|||||::...:.
Human   361 EMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNME-VSQLWSVLYFFMLLMLGIGSMLGNTAA 424

  Fly   425 IVTIICD-QFKGWKYWKVALTTSVC--GFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELA 486
            |:|.:.| :.......|.|::..||  ...:|:|:....|.:...:.:.|..|..:.::.:.|..
Human   425 ILTPLTDSKIISSHLPKEAISGLVCLVNCAIGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETI 489

  Fly   487 GIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSM---VTIEPIKY------- 541
            .:.:||||:.|..|::.|..|.||.||:|.|:..:|::::.:|::.:   :....:||
Human   490 AVCYVYGLRRFESDLKAMTGRAVSWYWKVMWAGVSPLLIVSLFVFYLSDYILTGTLKYQAWDASQ 554

  Fly   542 SELY---FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKPSDRWGPANP 600
            .:|.   :|..|.....||.|......||..|        ||:   ::..||..|    |:|
Human   555 GQLVTKDYPAYALAVIGLLVASSTMCIPLAAL--------GTF---VQRRLKRGD----ADP 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	183/563 (33%)
SLC6A20	NP_001372612.1	SLC6sbd_SIT1	2..588	CDD:271401	195/625 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810