DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NAAT1 and Gat

DIOPT Version :9

Sequence 1:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_651930.2	Gene:	Gat / 43805	FlyBaseID:	FBgn0039915	Length:	636	Species:	Drosophila melanogaster

Alignment Length:	625	Identity:	203/625 - (32%)
Similarity:	337/625 - (53%)	Gaps:	60/625 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SNGSSNGSGNG----------ATNAASTEKTDAEKPTA----------------ERTNWGNGLEF 47
            :|.:|:|.|.|          :.....|....:..||.                :|.:|.:.::|
  Fly     3 TNSASDGDGGGDVCKHESIEMSKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDF 67

  Fly    48 LMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSV 112
            ::|.:.:::|||||||||:..|:||||||::||||.|||.|.||:::|:.:||..:.|.:.::.:
  Fly    68 ILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKI 132

  Fly   113 VPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEW--TNCVNSRPQEYV- 174
            .|.|.|:||..|..:..:..||..:||..::|.|:|.::::||..|.:.|  .|||:...::.:
  Fly   133 APIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLH 197

  Fly   175 --DNLLTGVS--LANESARNLSGIVANDETEKLQSSSELYFLNVVIKEKLDISDG---VGDPDWK 232
              |.::.|.:  :.:.||.|::.:...|..::...           :..|.||.|   :|:..|:
  Fly   198 CWDKIINGTTQKVCSVSALNITSLELTDPVKEFWE-----------RRALQISHGIEEIGNIRWE 251

  Fly   233 LTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGE 297
            |...|.:.|::.:..|.:|||.:||..||.||||||:|.:||:|.:||.||.:||.|::.|.:.:
  Fly   252 LAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSK 316

  Fly   298 LLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILG 362
            |.|..||.:||.|.|||..:|.|.::...|||:|.:.:|:||:||.|:::.||:..|..||:::|
  Fly   317 LTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIG 381

  Fly   363 NLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVT 427
            .:||..| ..:.||..||.||||:.||.|:.:....| ::|.||||||.::|:.|........:|
  Fly   382 FMAHEQQ-RPVADVAASGPGLAFLVYPSAVLQLPGSP-MWSCLFFFMLLLIGLDSQFCTMEGFIT 444

  Fly   428 IICDQFKGW----KYWKVALTTSVC--GFLMGLVYVTPGGQWILTLVDFYG-GTYVVFILAIFEL 485
            .|.|:   |    :..|......||  .:|:||..:|.||.:|..::|.|. ..:.:..|..||.
  Fly   445 AIIDE---WPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFEC 506

  Fly   486 AGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAA 550
            ..|.|.||:..|.|.|:.|.....:::|:.||...||.:.:.:|.:::|...|:||.:..:|..|
  Fly   507 VSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWA 571

  Fly   551 NIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLK 590
            :..||..........||:..|...|.| |...:.::|.::
  Fly   572 HAFGWFTALSSMLYIPLYMFWLWKRTP-GELSEKIRALVR 610

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	179/509 (35%)
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	195/570 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440710
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850