DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NAAT1 and GlyT

DIOPT Version :9

Sequence 1:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster

Alignment Length:	638	Identity:	227/638 - (35%)
Similarity:	340/638 - (53%)	Gaps:	60/638 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QPSNGSSNGSG---------------NGATNAASTEKTDAEKPTA--------ERTNWGNGLEFL 48
            |.|...|.|.|               :|..:..:..:.||..|.|        ||..|....:||
  Fly     3 QSSKSGSAGVGGVGGGGGVVCPSTAISGCASGTALIQLDATGPGAGGAGESEHERGTWTGRFDFL 67

  Fly    49 MSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIW-SV 112
            :|.:..|||||||||||:..|.|||||||||:.|:|.:.|.|:.::|:..||:.:.|.|.:: ..
  Fly    68 LSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRF 132

  Fly   113 VPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWT-----------NCV 166
            .|.|.|:|.|....:..::.||:.::|.|::|:|.||...|||..|...|:           .|.
  Fly   133 CPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKYCFSYAQADQCE 197

  Fly   167 NSRPQEYVDNLLTGVSLANESARNLS-GIVANDETEKLQSSSELYFLNVVIKEKLDISDGVGDP- 229
            .:....|:.......|.|..:...|: |.:.....|:       ||.|.|    |.:|.|:.:.
  Fly   198 ATNGTYYLRTCHNATSAAENNITTLALGALKRPPAEE-------YFNNFV----LGLSKGIEETG 251

  Fly   230 DWKLTLA--LFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLE 292
            ..||:||  ||:||.::||.:.:||:||||..||.||||||||.:|.:|.|||.||..||||:|.
  Fly   252 SIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYLT 316

  Fly   293 PQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITI 357
            |.|.:|.|..||.:|.||.||:|:...|.:|..:|||:|.:..|:|::||...:..||...|:.|
  Fly   317 PDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLVI 381

  Fly   358 FAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQ 422
            |:|:|.|||.|.:: :..||..|.|||||.||:.:::....| :::||||.||..||:.|..||.
  Fly   382 FSIIGFLAHELNVD-VEKVVDQGAGLAFIVYPEVVTRLPVSP-VWAVLFFVMLLTLGLDSQFALM 444

  Fly   423 STIVTIICDQF---KGWKYWKVALTTSVCGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFE 484
            .|:.|.|.|:|   :.:|.| |.|:.::.|::.||.:.|..|.:.|.|:|.|...:.|.::||.|
  Fly   445 ETVTTAILDRFPNLRQYKIW-VVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYAANWSVLLIAISE 508

  Fly   485 LAGIVWVYGLQNFCDDIEFMCNRRV---SLYWRVCWSFFTPVMMIIIFIYSMVTIEPIKYSELYF 546
            ...|.|:||.|.|.:||:.|..:|.   :.:|.:.|.:.||..::.|..::.|..:|.||....:
  Fly   509 CILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGHYVY 573

  Fly   547 PEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKS-LKASLKPSDRWGPA 598
            |..|:..||::..:......|.....|.|.|....::. :|..|:|:..||||
  Fly   574 PMWADAVGWIVGLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAEWGPA 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	196/514 (38%)
GlyT	NP_611836.2	SNF	57..603	CDD:249680	207/559 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920