Protein Alignment NAAT1 and SLC6A18

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_872438.2
• Gene: SLC6A18 / 348932
• HGNCID: 26441
• Length: 628
• Species: Homo sapiens
• Alignment Length: 627
• Identity: 196/627 - (31%)
• Similarity: 302/627 - (48%)
• Gaps: 116/627 - (18%)

  Fly    37 ERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQF 101
            ||..|.|..::|:||...:|||||:||||:.....|||||||||:|.|...|.|::::|:.:||.
Human    17 ERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPIFHVELAIGQR 81

  Fly   102 TSQGTVKIWSVV-PGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWTNC 165
            ..:|:|.:|:.: |...|||.|....:..|..||::::|..|:||..|||..||||.|
Human    82 LRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQHPLPWSSC------- 139

  Fly   166 VNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSEL-YF-----LNVVIKEKLDISD 224
                |.:.                |.:|.|     |:.|.||.: ||     ||:.    .||:|
Human   140 ----PPDL----------------NRTGFV-----EECQGSSAVSYFWYRQTLNIT----ADIND 175

  Fly   225 GVGDPDWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILF 289
            . |...|.|.:.|..:|.|:::.::||::::||..||.|||||:||.:.|||.:||.||..|:::
Human   176 S-GSIQWWLLICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPGATKGLIY 239

  Fly   290 FLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGG 354
            ...|....|.||.||.:|..|.||||::..|..|.|||||...:...:||:::..::.:|||...
Human   240 LFTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTSLYAS 304

  Fly   355 ITIFAILGNLAHN---------------------------------------------------L 368
            |.:|::||..|.|                                                   .
Human   305 IAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKRVAQLPLKAC 369

  Fly   369 QIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICD-- 431
            .:|:..|...||.||||:.:.:........| ::::|||.|||.||:.::......::|.:.|
Human   370 LLEDFLDKSASGPGLAFVVFTETDLHMPGAP-VWAMLFFGMLFTLGLSTMFGTVEAVITPLLDVG 433

  Fly   432 QFKGWKYWKVALTTSVC--GFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGL 494
            ....| ..|.|||..||  .||....:....|.:.|.:.|.:..:..:.:||..|:.|:|:|||:
Human   434 VLPRW-VPKEALTGLVCLVCFLSATCFTLQSGNYWLEIFDNFAASPNLLMLAFLEVVGVVYVYGM 497

  Fly   495 QNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVTI-EPIKYS------ELY------- 545
            :.|||||.:|..||.|.|||:.|...:|:::.|...|.::.. :|::|.      ||:
Human   498 KRFCDDIAWMTGRRPSPYWRLTWRVVSPLLLTIFVAYIILLFWKPLRYKAWNPKYELFPSRQEKL 562

  Fly   546 FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKA 587
            :|..|..|..||..:.....|:..|..:....:.| |:...|
Human   563 YPGWARAACVLLSLLPVLWVPVAALAQLLTRRRRT-WRDRDA 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	180/554 (32%)
SLC6A18	NP_872438.2	SLC6sbd_B0AT3	17..591	CDD:212086	193/612 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	602..628		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810