Protein Alignment NAAT1 and SLC6A19

DIOPT Version :9

• Sequence 1: NP_572219.1
• Gene: NAAT1 / 31457
• FlyBaseID: FBgn0029762
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001003841.1
• Gene: SLC6A19 / 340024
• HGNCID: 27960
• Length: 634
• Species: Homo sapiens
• Alignment Length: 645
• Identity: 199/645 - (30%)
• Similarity: 319/645 - (49%)
• Gaps: 124/645 - (19%)

  Fly    28 KTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMY 92
            :|..::..:.|..|.|..:::::|:...||||||||||:....:|||||:||::|:|.|.|.|:.
Human    22 ETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLL 86

  Fly    93 YLEMIMGQFTSQGTVKIWSVV-PGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWS 156
            |||..:||...:|::.:||.: |...|:|......:..:..||:::::..::|||.|||..||||
Human    87 YLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWS 151

  Fly   157 YCRDEWTNCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVIKEKLD 221
            .|.      :|.....|||          |.||               ||...||.   .:|.|:
Human   152 DCP------LNENQTGYVD----------ECAR---------------SSPVDYFW---YRETLN 182

  Fly   222 ISDGVGDP---DWKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGA 283
            ||..:.|.   .|.:.|.|..||.|:::..:||::::|||.|..:..|||||.:.|||.:||:||
Human   183 ISTSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGA 247

  Fly   284 RDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTL 348
            .:||:|...|...||..|..|.:|..|.|||.::..|.:|.|:|||...:...:|::||:.::..
Human   248 TNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGF 312

  Fly   349 TSLLGGITIFAILGNLA-----------------------HNLQIENIRDVVR------------ 378
            ||:...|.:::::|..|                       .|:..||..|:.:
Human   313 TSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQ 377

  Fly   379 ----------------SGTGLAFISYPDAISKFQAVPQLFSVLFFFMLFVLGIGSIVALQSTIVT 427
                            .|||||||.:.:||:|....| |:|||||.|||.||:.|:......:|.
Human   378 LVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSP-LWSVLFFIMLFCLGLSSMFGNMEGVVV 441

  Fly   428 IICD-QFKGWKYWKVALTTSVC--GFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIV 489
            .:.| :....|:.|..||..:|  .||:|.::....||:.|:|:|.|.|:..:.|:|..|:..:|
Human   442 PLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFSVV 506

  Fly   490 WVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMV---------TIEPIKYSELY 545
            :|||:..|..|||||...:.:::|:|.|...:|::|:|||::..|         :|....|.|
Human   507 YVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYEE-- 569

  Fly   546 FPEAANIA--GW------LLFAIGAAQFPLWGLWYISR-HPQGTYWKSLKASLKPSDRWG 596
            ||::..|:  .|      ::..:.:...|.:.::.:.| |.|           ||.|..|
Human   570 FPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQ-----------KPGDHQG 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	181/550 (33%)
SLC6A19	NP_001003841.1	SLC5-6-like_sbd	32..612	CDD:294310	194/627 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810