DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment NAAT1 and ine

DIOPT Version :9

Sequence 1:	NP_572219.1	Gene:	NAAT1 / 31457	FlyBaseID:	FBgn0029762	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001162871.1	Gene:	ine / 33659	FlyBaseID:	FBgn0011603	Length:	943	Species:	Drosophila melanogaster

Alignment Length:	579	Identity:	200/579 - (34%)
Similarity:	318/579 - (54%)	Gaps:	40/579 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TEKTDAEKPTAERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKP 90
            :::|...||  .:.:|.|.::|:::||..|||||||||||:..|::|||.||:||.|:||:...|
  Fly   327 SDETAQLKP--RQQHWANKMQFVLACIGYSVGLGNVWRFPYMCYKSGGGVFLVPYCIILFICSIP 389

  Fly    91 MYYLEMIMGQFTSQGTV-KIWSVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELP 154
            :.::|:.:||:|.:|.: .:..:.|.|.|.|......:..:.:|||.::..::||.|.||::|:|
  Fly   390 LLFMELSVGQYTGRGPIGALGQLCPLFKGAGLASVVVSFLMSTYYSVIIGYSIYYFFTSFKTEMP 454

  Fly   155 WSYCRDEWTNCVNSRPQEYVDNLLTGVSLANESARNLSGIVANDETEKLQSSSELYFLNVVIKEK 219
            |..|.:.|.......||.      .|:   |.||.:.|           ::.||.:|.|.|
  Fly   455 WIDCNNRWNTPDCWVPQR------KGI---NASAPDTS-----------RTPSEEFFENKV---- 495

  Fly   220 LDISDGVGDPD---WKLTLALFVAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLE 281
            |.||.|:..|.   |:|...|..||::::....:.:|||.|..||.|.||:|::.:|::|||||:
  Fly   496 LQISGGLEYPGMMRWELFACLICAWLMVYFATWKSIKSSAKVRYFTATFPFVLIIILMVRAVTLD 560

  Fly   282 GARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLD 346
            ||.:|:.||..|:|.||.|..||..|..|.|.||.:..|.:|.|||||::::.|.||.:.|:.::
  Fly   561 GAAEGLRFFFRPKWSELKNANVWINAASQNFNSLGITFGSMISFASYNKYNNNILRDTVAVSAVN 625

  Fly   347 TLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFQAVPQLFSVLFFFMLF 411
            .:||||.||..|:.|||||.. |..|:|||:..|.|:.|:.||.|::| ....||::|:|||||.
  Fly   626 MITSLLVGIFAFSTLGNLALE-QNTNVRDVIGDGPGMIFVVYPQAMAK-MPYAQLWAVMFFFMLL 688

  Fly   412 VLGIGSIVALQSTIVTIICDQFKGW-----KYWK-VALTTSVCGFLMGLVYVTPGGQWILTLVDF 470
            .||:.|..|:...:||.|.|.|..|     .|.: |.|...|...|.|:..:..||.:...|:|.
  Fly   689 CLGLNSQFAIVEVVVTSIQDGFPRWIKRHLGYHEIVVLFVCVISCLFGMPNIIQGGIYYFQLMDH 753

  Fly   471 YGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRVCWSFFTPVMMIIIFIYSMVT 535
            |..:..:..||..::..|.|.||......:::.|..:..|.|.|.||....|.::..|::.|::.
  Fly   754 YAASVTIMFLAFCQMIAIAWFYGTGRLSKNVKQMTGKAPSFYLRSCWLVLGPCLLFAIWVLSLIN 818

  Fly   536 I-EPIKYSELY-FPEAANIAGWLLFAIGAAQFPLWGLWYISRHPQGTYWKSLKASLKPS 592
            . ||..::..| :|:.|...||:..:......|.:.:....|....|:|:.::.:|:|:
  Fly   819 YHEPTYHNGRYTYPDWAYGIGWMFASFSLICIPGYAVINFLRSSGDTFWERIRNTLRPN 877

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NAAT1	NP_572219.1	SLC6sbd	40..533	CDD:271359	183/502 (36%)
ine	NP_001162871.1	SLC5-6-like_sbd	337..876	CDD:294310	196/564 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440772
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850